Doctoral Position: Development of an Organ-on-chip platform

Academic Positions; Schweiz; In loco; CHF 28.000 - 36.000; Part-time

Descrizione del lavoro

ETH Zürich’s Bioanalytics Group in Basel, Switzerland, invites applications for a Doctoral Position focused on developing an organ-on-chip model system. The project combines engineering and biology to create microphysiological platforms for studying cancer metastasis and vascularized tissue models.

You will design microfluidic devices, optimize assays, and analyze time-lapse imaging data, ultimately contributing to peer‑reviewed publications.

Competenze

• Master's degree in microsystems engineering, biomedical engineering or interdisciplinary study programmes.
• Experience with designing and fabricating microfluidic platforms.
• Strong interest in technology development across biology and engineering.
• Ability to communicate across disciplines in English.

Mansioni

• Design and manufacture a microfluidic platform.
• Develop, optimize and test biological assays.
• Perform imaging (time-lapse microscopy), data analysis and interpretation.
• Publish findings in peer-reviewed journals.
• Participate actively in group meetings and collaborative research discussions.
• Interact and collaborate with group members and collaboration partners.

Conoscenze

Microfluidics experience

English communication

Teamwork skills

Interdisciplinary communication

Adaptability

Formazione

Master's degree in microsystems engineering, biomedical engineering or interdisciplinary study programmes

Descrizione del lavoro

Organisation/Company ETH Zürich Research Field Biological sciences » Other Engineering » Biomedical engineering Engineering » Materials engineering Engineering » Systems engineering Engineering » Other Technology » Biotechnology Researcher Profile First Stage Researcher (R1) Application Deadline 25 Jan 2027 - 22:59 (UTC) Country Switzerland Type of Contract Temporary Job Status Part-time Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

Doctoral Position: Development of an Organ-on-chip platform

The Bioanalytics Group at ETH Zürich in Basel (Switzerland) is developing so-called lab-on-chip technology (or microfluidic technology) for applications across the life sciences and biomedicine. Our interdisciplinary approach includes the design and manufacturing of miniaturized platforms and their optimization for biochemical assays and analytical procedures. To strengthen our team, we are offering a Doctoral Positionfor developing an organ-on-chip model system.

Project background

Organ-on-chip systems, also known as microphysiological systems, are promising platforms for investigating disease development and evaluating potential treatments. Their miniaturized design enables the reproducible and controlled formation of human tissues with specific functions, as well as the parallelized study of biological processes.

In the Bioanalytics Group, we are developing vascularized tissue models to investigate how cells, cell-secreted molecules, and drugs cross the endothelial barrier to reach surrounding tissues and how compounds translocate from tissue into the blood stream.

As part of a project focused on understanding the mechanisms underlying cancer metastasis, we are looking for a motivated Doctoralstudent interested in experimental research at the interface of engineering and biology.

• Design and manufacture a microfluidic platform
• Develop, optimize and test biological assays
• Perform imaging (time-lapse microscopy), data analysis and interpretation
• Publish findings in peer-reviewed journals
• Participate actively in group meetings and collaborative research discussion meeting
• Interact and collaborate with other members of the group and collaboration partners

Profile

• Master`s degree in microsystems engineering, biomedical engineering or interdisciplinary study programmes
• Candidates with background in biology, bioengineering, biotechnology, material sciences or microbiology, with a strong interest in technology development, are welcome to apply as well
• Experiences in the field of microfluidics
• The combination of biological and technological aspects is central in our group and in this project
• A possible candidate should have strong disposition to learn and improve novel methods, should be very open to different research disciplines and should be able to communicate across disciplines
• Good communication (in English) and teamwork skills

We offer

• An intellectually challenging position in the inspiring atmosphere of an interdisciplinary team, and the prospect to obtain a Doctoral degree from ETH Zurich
• Applied work in a multidisciplinary team
• Advanced training in different related fields and participation at international conferences is highly encouraged

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