Doctoral Position: Development of an Organ-on-chip platform

ETH Zurich; Basel; On-site; CHF 60,000 - 75,000; Full time

Benefits offered by this job

Interdisciplinary team environment

Doctoral degree from ETH Zurich

International conference participation

Job summary

ETH Zurich's Bioanalytics Group in Basel invites applications for a Doctoral Position to develop an organ-on-chip model system by designing and manufacturing a microfluidic platform.

You will develop, optimize and test biological assays, perform time-lapse imaging, analyze data and publish results while collaborating with group members and partners. The role provides interdisciplinary training toward a doctoral degree from ETH Zurich.

Qualifications

• Master’s degree in microsystems engineering or biomedical engineering or interdisciplinary study programmes.
• Candidates with background in biology, bioengineering, biotechnology, material sciences or microbiology welcome.
• Experiencing microfluidics and cross-disciplinary communication are valued.
• Strong disposition to learn and collaborate across disciplines.

Responsibilities

• Design and manufacture a microfluidic platform.
• Develop, optimize and test biological assays.
• Perform time-lapse imaging, data analysis and interpretation.
• Publish findings in peer-reviewed journals.
• Participate in group meetings and collaboration discussions.
• Interact with group members and collaboration partners.

Skills

Microfluidics experience

English communication

Teamwork

Education

Master's degree in microsystems engineering

Master's degree in biomedical engineering

Interdisciplinary study programmes

Job description

Doctoral Position: Development of an Organ-on-chip platform

The Bioanalytics Group at ETH Zürich in Basel (Switzerland) is developing so-called lab-on-chip technology (or microfluidic technology) for applications across the life sciences and biomedicine. Our interdisciplinary approach includes the design and manufacturing of miniaturized platforms and their optimization for biochemical assays and analytical procedures. To strengthen our team, we are offering a Doctoral Positionfor developing an organ-on-chip model system.

Project background

Organ-on-chip systems, also known as microphysiological systems, are promising platforms for investigating disease development and evaluating potential treatments. Their miniaturized design enables the reproducible and controlled formation of human tissues with specific functions, as well as the parallelized study of biological processes.

In the Bioanalytics Group, we are developing vascularized tissue models to investigate how cells, cell-secreted molecules, and drugs cross the endothelial barrier to reach surrounding tissues and how compounds translocate from tissue into the blood stream.

As part of a project focused on understanding the mechanisms underlying cancer metastasis, we are looking for a motivated Doctoralstudent interested in experimental research at the interface of engineering and biology.

• Design and manufacture a microfluidic platform
• Develop, optimize and test biological assays
• Perform imaging (time-lapse microscopy), data analysis and interpretation
• Publish findings in peer-reviewed journals
• Participate actively in group meetings and collaborative research discussion meeting
• Interact and collaborate with other members of the group and collaboration partners

Profile

• Master`s degree in microsystems engineering, biomedical engineering or interdisciplinary study programmes
• Candidates with background in biology, bioengineering, biotechnology, material sciences or microbiology, with a strong interest in technology development, are welcome to apply as well
• Experiences in the field of microfluidics
• The combination of biological and technological aspects is central in our group and in this project
• A possible candidate should have strong disposition to learn and improve novel methods, should be very open to different research disciplines and should be able to communicate across disciplines
• Good communication (in English) and teamwork skills

We offer

• An intellectually challenging position in the inspiring atmosphere of an interdisciplinary team, and the prospect to obtain a Doctoral degree from ETH Zurich
• Applied work in a multidisciplinary team
• Advanced training in different related fields and participation at international conferences is highly encouraged

In line with our values , ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value diversity and nurture a working and learning environment in which the rights and dignity of all our staff and students are respected. Visit our Equal Opportunities and Diversity website to find out how we ensure a fair and open environment that allows everyone to grow and flourish. Sustainability is a core value for us – we are consistently working towards a climate-neutral future .

We would like to point out that the pre-selection is carried out by the responsible recruiters and not by artificial intelligence.

Further information about the Departmentand the Institute can be found on the following Websites: D-BSSE and Bioanalytics Group . Questions regarding the position should be directed to Prof. Petra S. Dittrich, [e-mail]

ETH Zurich is one of the world’s leading universities specialising in science and technology. We are renowned for our excellent education, cutting-edge fundamental research and direct transfer of new knowledge into society. Over 30,000 people from more than 120 countries find our university to be a place that promotes independent thinking and an environment that inspires excellence. Located in the heart of Europe, yet forging connections all over the world, we work together to develop solutions for the global challenges of today and tomorrow.