CMC-Development Associate, DSP (100%)

LimmaTech Biologics AG; Schlieren; On-site; CHF 90,000 - 120,000; Full time

Job summary

LimmaTech Biologics AG, a Swiss biopharmaceutical company, seeks a CMC-Development Associate, DSP (100%) to advance robust and scalable purification processes for vaccine development. Work in Schlieren near Zürich, contributing to DSP experiments and technology transfer under supervision.

You will operate sophisticated lab equipment (FPLC, TFF, filtration) and document results, collaborating across teams to ensure quality and compliance in process development.

Qualifications

• A Technician qualification, BSc, or MSc in biotechnology, bioprocess engineering, food technology, or a related discipline.
• Hands‑on experience in protein purification, including chromatography/FPLC and filtration technologies such as TFF.
• A strong technical aptitude and enthusiasm for working with sophisticated laboratory and process equipment.
• Practical knowledge of biochemical and analytical methods, such as SDS‑PAGE, Western blotting, HPLC, and UV-based measurements.
• Knowledge of or experience with Design of Experiments (DoE) approaches is an advantage.
• A structured, reliable, and solution‑oriented working style, with the ability to work both independently and collaboratively within a team.
• Good written and verbal communication skills in English; additional languages are an advantage.

Responsibilities

• Prepare, perform, and document DSP operations and experiments in accordance with established plans, timelines, and project priorities.
• Develop robust and scalable purification processes suitable for subsequent GMP manufacturing under the guidance of experienced team members, using state-of-the-art equipment such as FPLC systems, microfiltration, depth filtration, and tangential flow filtration (TFF) systems.
• Establish and execute experimental strategies to investigate chromatography methods and resins, filtration technologies, and critical process parameters, with the aim of identifying optimal purification conditions for novel products.
• Establish & perform in-process controls (IPC) to characterize process intermediates and purified material to support process development and monitor purification performance.
• Evaluate and interpret experimental data and communicate results and conclusions in scientific meetings, presentations, and technical reports.
• Support technology transfer activities to contract manufacturing organizations (CMOs) throughout different stages of development.
• Help ensure that laboratories and equipment are maintained in a clean, safe, and fully operational condition in accordance with applicable safety and operational standards.

Skills

Hands-on laboratory work

DoE knowledge

English communication

Education

Bachelor’s degree in biotechnology / bioprocess engineering / related

Tools

FPLC systems

Microfiltration

Depth filtration

Tangential flow filtration (TFF)

SDS-PAGE

Western blotting

HPLC

UV-based measurements

DoE (advantage)

Job description

CMC-Development Associate, DSP (100%)

LimmaTech Biologics AG, a wholly owned subsidiary of Eli Lilly and Company, is a Swiss based clinical stage biopharmaceutical company. We are advancing our vaccine pipeline to halt the increasing threat of global infections due to emerging antimicrobial resistance (AMR) and sexually transmitted diseases. Working at LimmaTech is a unique chance to be part of the development of life saving vaccines.

Are you excited about the opportunity to contribute to the development of early- to mid -stage vaccines by developing innovative protein purification processes using your technical and scientific skills? Would you like to be part of a team establishing scalable and GMP-compatible manufacturing processes to produce lifesaving vaccines?

To strengthen our Downstream Processing (DSP) team, we are currently looking for a CMC-Development Associate, DSP (100%) to contribute to the development of robust and scalable manufacturing processes.

Your responsibilities

In this role, you will:

• Prepare, perform, and document DSP operations and experiments in accordance with established plans, timelines, and project priorities.
• Develop robust and scalable purification processes suitable for subsequent GMP manufacturing under the guidance of experienced team members, using state-of-the‑art equipment such as FPLC systems, microfiltration, depth filtration, and tangential flow filtration (TFF) systems.
• Establish and execute experimental strategies to investigate chromatography methods and resins, filtration technologies, and critical process parameters, with the aim of identifying optimal purification conditions for novel products.
• Establish & perform in-process controls (IPCs) to characterize process intermediates and purified material to support process development and monitor purification performance.
• Evaluate and interpret experimental data and communicate results and conclusions in scientific meetings, presentations, and technical reports.
• Support technology transfer activities to contract manufacturing organizations (CMOs) throughout different stages of development.
• Help ensure that laboratories and equipment are maintained in a clean, safe, and fully operational condition in accordance with applicable safety and operational standards.

What we are looking for

You are a curious, enthusiastic, and proactive team player who enjoys hands on laboratory work, takes ownership of your activities, and is motivated to continuously learn and develop in a laboratory-focused technical role. Ideally, you bring:

• A Technician qualification, BSc, or MSc in biotechnology, bioprocess engineering, food technology, or a related discipline.
• Hands‑on experience in protein purification, including chromatography/FPLC and filtration technologies such as TFF.
• A strong technical aptitude and enthusiasm for working with sophisticated laboratory and process equipment.
• Practical knowledge of biochemical and analytical methods, such as SDS‑PAGE, Western blotting, HPLC, and UV-based measurements.
• Knowledge of or experience with Design of Experiments (DoE) approaches is an advantage.
• A structured, reliable, and solution‑oriented working style, with the ability to work both independently and collaboratively within a team.
• Good written and verbal communication skills in English; additional languages are an advantage.

The working place is in Schlieren near Zürich, easily accessible by public transportation.

• Work location 8952 Schlieren (ZH)
• Workload 100%
• Employment start By agreement
• Employment duration Permanent

• Qualification skilled
• Work experience More than 3 years
• Education Bachelor’s degree from a university or equivalent

• English Orally : Good knowledge Written : Good knowledge

• By email [e-mail]