Clinical Pharmacology Trial Lead — FIH & Early Phase

Novartis AG; Basel; Hybrid; CHF 94,000 - 174,000; Full time

Benefits offered by this job

Hybrid working options

Parental leave (14+ weeks)

Wellbeing resources

Job summary

Novartis AG in Basel seeks a Clinical Sciences Trial Leader (CSTL) to lead clinical pharmacology trials, including FIH studies, ensuring high-quality data for key program decisions. You will bridge Novartis with CROs, guiding protocol development, study start-up, conduct, and CSR delivery.

The role emphasizes hands-on leadership, cross-functional collaboration, and a strong commitment to scientific and operational excellence, with flexible Basel-based hybrid work安排.

Qualifications

• Bachelor’s degree in life sciences or healthcare required; MSc/PhD/PharmD/MD or equivalent preferred.
• Experience in clinical pharmacology or early clinical development, ~2+ years.
• Demonstrated experience leading first-in-human and/or clinical pharmacology studies.
• Strong protocol development and early phase study design skills.
• Proven ability to deliver studies through external partners (CROs).
• Strong study leadership and cross-functional coordination in a matrix environment.
• Excellent communication and stakeholder management; ownership and accountability.
• Solid understanding of ICH GCP and regulatory requirements.

Responsibilities

• Provide operational leadership for clinical pharmacology studies, including FIH and early-phase trials.
• Act as independent CSTL for end-to-end study delivery from protocol to CSR.
• Lead protocol synopsis development with cross-functional partners.
• Serve as primary Novartis CRO contact with guidance and oversight.
• Coordinate internal study teams to align CRO activities.
• Oversee study start-up, conduct, and closeout with risk mitigation.
• Review clinical study data (PK/PD/safety) to inform decisions.
• Contribute to CSRs and program updates with scientific rigor and traceability.
• Share lessons learned and foster collaboration and accountability.

Skills

Clinical pharmacology

Early clinical development

Protocol development

Study delivery

CRO management

Cross-functional leadership

Data interpretation

Regulatory knowledge

Education

Bachelor’s degree in life sciences or healthcare

Advanced degree (MSc, PhD, PharmD, MD) preferred

Job description

Novartis AG in Basel seeks a Clinical Sciences Trial Leader (CSTL) to lead clinical pharmacology trials, including FIH studies, ensuring high-quality data for key program decisions. You will bridge Novartis with CROs, guiding protocol development, study start-up, conduct, and CSR delivery.

The role emphasizes hands-on leadership, cross-functional collaboration, and a strong commitment to scientific and operational excellence, with flexible Basel-based hybrid work安排.