Clinical Operational Manager

Novocure; Schweiz; Hybrid; CHF 130,000 - 170,000; Full time

Benefits offered by this job

Hybrid working model

Flexible schedule

Job summary

Novocure is seeking a Clinical Operational Manager to coordinate a global Phase III drug-device study across Europe, the US, Canada and Japan. You will lead operational delivery, oversee CROs, and partner with cross‑functional teams to maintain study plans and regulatory readiness.

You'll bring 5+ years in clinical research, strong project management, and hands-on leadership to drive risk management, data integrity, and timely study milestones in a fast-paced, collaborative environment.

Qualifications

• 5+ years of clinical research experience, with 2–3 years in study management.
• Global project management experience in Phase II or Phase III studies.
• Proficiency with CTMS, eTMF, EDC, IRT and ePRO.
• Ability to work independently and lead cross‑functional teams.
• Strong knowledge of ICH-GCP and regulatory requirements.

Responsibilities

• Coordinate global Phase III study operations and CRO oversight.
• Lead Clinical Study Team and act as deputy for the Clinical Trial Lead.
• Manage study logistics, supply, and budgets with cross‑functional partners.
• Maintain study systems and ensure regulatory readiness.
• Provide regular updates to governance bodies.
• Support budget forecasting and vendor activities.

Skills

Clinical research

Project management

Global coordination

CRO oversight

Regulatory knowledge

Independent work

Education

Bachelor's degree in Life Sciences / Nursing / Pharmacy

Advanced degree preferred

Tools

CTMS

eTMF

EDC

IRT

ePRO

Job description

Select how often (in days) to receive an alert: Create Alert

At Novocure, every role contributes to extending the lives of people living with cancer. As our new Clinical Operational Manager, you’ll play a key part in this mission.

You will be a key member of the Clinical Study Team, coordinating the operational delivery of a complex global Phase III drug-device combination study across Europe, the United States, Canada, and Japan. Reporting to the Global Clinical Operational Lead, you will work closely with the Clinical Trial Lead and cross-functional partners, act as a trusted escalation point, and step in as deputy or assume study leadership when assigned.

This role calls for hands‑on ownership, sound project management judgment, and the confidence to work independently while connecting and escalating early when needed. In your first 6–12 months, success will mean strengthening CRO and vendor oversight, helping reduce operational and data‑cleaning backlogs, embedding required SOPs and processes, and creating greater capacity for the Clinical Trial Lead during the study’s maintenance phase.

WHAT YOU’LL DO

• You will combine operational coordination with practical problem-solving to keep the study moving efficiently, compliantly, and collaboratively.
• Serve as a core member of the Clinical Study Team and act as deputy for the Clinical Trial Lead during absences or as assigned.
• Coordinate Clinical Study Team meetings, including agendas, minutes, decisions, follow-up actions, and clear communication across internal and external partners.
• Drive day‑to‑day operational delivery of a global Phase III drug‑device combination study, coordinating study conduct as well as drug and device supply requirements.
• Oversee CRO and vendor performance with a hands‑on, detail‑oriented approach; ask the right questions, challenge delivery where needed, track corrective actions, and elevate issues appropriately.
• Partner across functions to develop and maintain study‑level project management, communication, risk management, quality, and operational plans.
• Establish and manage study systems and processes, including central laboratories, eCOA/ePRO, clinical supplies, data integration, transfer, and reconciliation, in line with protocol requirements.
• Identify operational risks, issues, and process gaps; develop and implement mitigation plans, including the practical application of Novocure SOPs and required processes with external partners.
• Maintain accurate study information in tracking and communication systems and provide regular updates to internal governance bodies.
• Coordinate clinical trial insurance and partner with global supply chain colleagues to support the timely distribution of study drugs and devices to sites.
• E nsure ongoing inspection and audit readiness andparticipate in internal audits and regulatory inspections as required.
• Support budget forecasting, accruals, invoice tracking, and invoice processing; appropriately challenge CRO activities or costs that fall outside agreed scope.
• Lead logistics and support content development for external meetings, including investigator meetings and advisory boards.
• Act as Clinical Trial Lead when assigned, providing calm, collaborative leadership across the cross‑functional study team.

ABOUT YOU

• Bachelor’s degree in Life Sciences, Nursing, Pharmacy, or a related field.
• Minimum 5 years of clinical research experience, including 2–3 years in clinical study management or clinical operations.
• Global project management experience in Phase II or Phase III studies.
• Proven experience overseeing CRO‑managed studies and managing vendor performance in global, cross‑functional settings.
• Pharmaceutical clinical development experience and strong knowledge of ICH‑GCP, ISO standards, regulatory requirements, and clinical study processes.
• Proficiency with CTMS, eTMF, and clinical systems such as EDC, IRT, and ePRO.
• Ability to work independently, dig into operational detail, collaborate across multiple departments, and elevate constructively whenrequired.

These additional qualifications are preferred:

• Advanced degree in a relevant field.
• Experience with late‑phase or pivotal studies, blinded clinical trials, oncology, or medical devices.
• Experience working within a small or mid‑sized sponsor environment, or broad CRO experience that provides a strong understanding of sponsor needs and decision‑making.
• Experience with budget tracking, invoice review, financial forecasting, and challenging out‑of‑scope vendor activity.
• A proactive, detail‑oriented, and quality‑focused mindset, with the judgment to balance accountability and challenge with a collaborative, team‑oriented style.
• Strong interpersonal and communication skills, a continuous improvement mindset, and the ability to thrive in a complex, fast‑paced environment without being overly aggressive.

NOVOFLEX

We offer a flexible, trust‑based hybrid working model for most of our office‑based roles. Employees are asked to be in the office an average of three days per week, with the flexibility to choose which days’ work best for them. We understand that life is not always predictable, so if you need to adjust your schedule, such as leaving early or starting late occasionally, we trust you to balance your time in a way that works for both you and Novocure.

ABOUT NOVOCURE

Novocure is a company with a powerful mission, to extend the lives of people living with some of the most aggressive forms of cancer. Here your work will have a direct impact on patients and those who care about them. Join a team of passionate, collaborative people who support each other, challenge one another, and innovate together. Here, you’ll connect, grow, and make a real difference. We’re a company with the drive of a startup and the strength that comes with 25 years of success.

Novocure operates at a rare crossroad, where advanced medical technology converges with cutting‑edge biotechnology. We are the only company to develop and commercialize Tumor Treating Fields (TTFields), a proprietary, groundbreaking therapy designed to disrupt cancer cell division. With us you will find a unique combination of laboratory research work alongside engineering development of advanced technologies. This fusion of disciplines positions us as true pioneers in oncology innovation, leading a new frontier in the treatment of aggressive cancers.

• innovation
• focus
• drive
• courage
• trust