Automation-Driven Synthesis Scientist

F. Hoffmann-La Roche AG; Basel; Vor Ort; CHF 120.000 - 180.000; Vollzeit

Zusammenfassung

Roche in Basel seeks a Scientist in Synthesis Automation to accelerate small-molecule synthesis through automation and digitalization. You will expand and execute parallel chemistry and late-stage functionalization, introducing novel synthetic methods, miniaturized reaction setups, and rapid purification strategies.

You will design and run high-throughput experiments, coordinate with CRO partners, and guide parallel synthesis across Basel, Shanghai, and San Francisco, contributing to data

Qualifikationen

• PhD in Synthetic Organic Chemistry with at least four years of industry experience.
• Expertise in automation technology integrated with analytical and purification methods.
• Experience with digital labs and reaction datasets for ML applications.

Aufgaben

• Design and execute multi-step organic synthesis and purification for drug candidates.
• Perform high-throughput, miniaturized experiments using automation tools.
• Develop and implement new synthetic methodologies and miniaturization techniques.
• Collaborate with project teams and CROs across Europe and Asia-Pacific.
• Lead internal teams and coordinate parallel synthesis across Basel, Shanghai, and San Francisco.

Kenntnisse

Synthetic organic chemistry

Automation technology

Lab digitalization

Machine learning concepts

Reaction dataset collection

Parallel medicinal chemistry

Cross-functional collaboration

Team leadership

Ausbildung

PhD in Synthetic Organic Chemistry

Tools

Automation equipment

Solid dosing

Liquid handling

Analytical purification

Jobbeschreibung

Roche in Basel seeks a Scientist in Synthesis Automation to accelerate small-molecule synthesis through automation and digitalization. You will expand and execute parallel chemistry and late-stage functionalization, introducing novel synthetic methods, miniaturized reaction setups, and rapid purification strategies.

You will design and run high-throughput experiments, coordinate with CRO partners, and guide parallel synthesis across Basel, Shanghai, and San Francisco, contributing to data