Upstream Process Development Scientist – Biologics

STICA STEMCELL Technologies Canada Inc.; Burnaby; On-site; CAD 86,000 - 129,000; Full time

Job summary

STEMCELL Technologies Canada Inc., a Vancouver-based biotechnology company, seeks a Scientist to lead upstream process development for protein production in a cGMP environment. You will design experiments, optimize scale-up, and transfer processes to manufacturing, collaborating across R&D, QA, and external CDMOs.

You will contribute as a SME, analyze data, and implement robust workflows for biologics production, supporting regulatory compliance and continuous improvement.

Qualifications

• Bachelor's with 6+ years, Masters with 4-8 years or PhD with 2-5 years of relevant experience.
• Deep understanding and practical expertise in upstream protein production process development, including optimization and scale-up using mammalian cell lines in cGMP environments.
• Experience with Design of Experiments (DoE), statistical methods, and Quality by Design (QbD) principles.
• Experience in technology transfer to manufacturing facilities, including CDMOs.

Responsibilities

• Act as a SME, providing technical recommendations to cross-functional project teams for upstream process development supporting cGMP protein manufacturing
• Oversee upstream development activities, including design, risk assessment, development, and transfer of safe, efficient, and robust processes
• Analyze experimental data, presenting conclusions and findings to cross-functional teams, and develop and transfer SOPs into manufacturing
• Lead and participate in non-conformance root cause investigations, supporting the execution of CAPAs
• Collaborate internally with R&D, Quality Control, Quality Assurance & Regulatory teams, and externally with CDMOs

Skills

Upstream process development

Scale-up

Design of Experiments

Quality by Design

CDMOs

Education

Bachelor's degree

Master's degree

PhD

Job description

STEMCELL Technologies Canada Inc., a Vancouver-based biotechnology company, seeks a Scientist to lead upstream process development for protein production in a cGMP environment. You will design experiments, optimize scale-up, and transfer processes to manufacturing, collaborating across R&D, QA, and external CDMOs.

You will contribute as a SME, analyze data, and implement robust workflows for biologics production, supporting regulatory compliance and continuous improvement.