Staff Scientist, Computational Biology - Toronto

Recursion; Old Toronto; Hybrid; CAD 251,000 - 280,000; Full time

Job summary

Join a pioneering TechBio company that is revolutionizing drug discovery through advanced computational biology. As a Staff Scientist in Computational Biology, you will play a crucial role in integrating vast datasets to identify promising therapeutic candidates. Your expertise will drive innovative strategies for patient selection and indication expansion, ensuring that life-changing therapies reach those in need. This dynamic role offers the opportunity to collaborate with a diverse team of scientists, utilizing cutting-edge technology and methodologies to transform the future of medicine. If you are passionate about making a significant impact in the biotech field, this position is an exciting opportunity to advance your career.

Benefits

Comprehensive benefits package

Bonuses

Equity compensation

Qualifications

• 5+ years in biotech/pharma with a focus on oncology or drug discovery.
• Strong computational focus with experience in data integration.

Responsibilities

• Lead computational strategies for drug programs in oncology.
• Collaborate with teams to analyze and validate clinical data.

Skills

Computational Biology

Data Analysis

Machine Learning

Statistical Techniques

Data Visualization

Cross-functional Communication

Education

PhD in Computational Biology or related field

MS in relevant field

Tools

Python

R

Job description

Staff Scientist, Computational Biology - Toronto

Please Note: Our offices will be closed for our annual Winter Break from Monday, December 23, 2024, through Thursday, January 2, 2025. Our response to your application will be delayed.

Your work will change lives. Including your own.

The Impact You’ll Make

As a key member of Recursion's portfolio-facing data science team, you will be at the forefront of reimagining drug discovery from first principles using Recursion’s massive data and compute capabilities. You will be the primary computational lead for a portfolio of preclinical or clinical-stage drug programs and will be responsible for collaboratively defining and executing a research strategy that defines the most promising patient populations for our therapeutics entering the clinic. You will integrate matched molecular and clinical data from oncology patients with layers of Recursion platform data (phenomics, transcriptomics, proteomics, etc) to validate the link between target and disease biology and propose clinical development opportunities. You will partner with machine learning and computational scientists from across the organization to develop, deploy, and scale novel approaches to patient selection and indication expansion that match the medicines we are creating to the patients who need them.

In this role, you will:

• Evaluate new data sources, develop and scale new analysis methods, and drive key program decisions with the ultimate goal of bringing life-changing therapies to patients at unprecedented speed.
• Evaluate the molecular evidence for therapeutic hypotheses and accelerate drug program progression into the clinic, primarily in oncology.
• Pilot novel methods for patient stratification and indication selection or expansion in oncology.
• Deliver biological insights on therapeutic candidates and disease biology from the analysis of high dimensional (phenomics, transcriptomics, proteomics, patient-derived) datasets that support clinical development planning.
• Present data analysis to decision makers and stakeholders in a clear and compelling way that drives toward getting medicines to patients.
• Industrialize analysis approaches to not only solve for the current project, but also to accelerate future projects and scale the impact that we can have.
• Collaborate cross-functionally with Recursion’s data science, platform, ML and clinical teams to further advance Recursion’s ability to interpret and translate large-scale data assets into therapeutic programs.

The Team You’ll Join

Our group is a bold, agile, diverse collective of computational drug discovery scientists deeply focused on the singular goal of bringing new therapeutics into the clinic at an accelerated pace. You will collaborate extensively with scientists across the organization to advance milestones, provide insights and drive decisions that further advance Recursion’s capabilities and likelihood of success in the clinic. Essential attributes to this role include a bold, execution-first attitude and passion for deploying rigorous science to develop life-changing medicines. Our team collaborates extensively with computational biologists in other therapeutic areas (neurobiology, immunology, etc.) as well as data scientists and engineers from our core platform teams to provide a strong network of feedback and support.

The Experience You’ll Need

• PhD in a relevant field (computational biology, systems biology, bioinformatics, cancer/cell biology, etc.) with a very strong computational focus and 5+ years of experience in biotech or pharma industry solving fundamental problems in oncology or drug discovery OR MS in a relevant field and 7+ years of experience in biotech or pharma industry solving fundamental problems in oncology or drug discovery.
• Experience applying computational methods (including probabilistic, statistical, and/or machine learning techniques) to analyze and integrate matched human clinical and molecular data in a high level programming language such as Python or R.
• Experience in efficiently advancing drug programs from proof of concept and into clinical development.
• Deep expertise in the analysis and data integration of two or more ‘omics data modalities (phenomics, transcriptomics, proteomics, genomics), including experience working with patient data.
• Exceptional data visualization skills.
• Excellent cross-functional communication skills, including an ability to explain complex scientific concepts to a variety of audiences using a combination of plots, documents, and presentations.

Nice To Have:

• Experience analyzing data from imaging-based modalities.
• Experience with oncology clinical trial biomarker analysis.
• Experience working collaboratively with biometrics and statistical sciences.

Working Location:

This position is ideally based at one of our offices located in Toronto / New York City / Salt Lake City / London. Please note that we are a hybrid environment and ask that employees spend 50% of their time in the office.

At Recursion, we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role, the estimated current annual base range for this role is:

• Developing: $251,000 CAD
• Expert: $280,000 CAD

You will also be eligible for bonuses and equity compensation + our comprehensive benefits package for Canada based candidates. The range displayed on each job posting reflects target ranges for Canadian new hire salaries and is determined by job, level, and market factors.

During the interview selection process, you will connect with a Talent Acquisition Partner who will be your advocate and ally to ensure you receive the appropriate compensation that meets your needs for your skills, experience, and relevant education/training, while also reviewing our very competitive total rewards package.

The Values That We Hope You Share:

• We Care: We care about our drug candidates, our Recursionauts, their families, each other, our communities, the patients we aim to serve and their loved ones. We also care about our work.
• We Learn: Learning from the diverse perspectives of our fellow Recursionauts, and from failure, is an essential part of how we make progress.
• We Deliver: We are unapologetic that our expectations for delivery are extraordinarily high. There is urgency to our existence: we sprint at maximum engagement, making time and space to recover.
• Act Boldly with Integrity: No company changes the world or reinvents an industry without being bold. It must be balanced; not by timidity, but by doing the right thing even when no one is looking.
• We are One Recursion: We operate with a 'company first, team second' mentality. Our success comes from working as one interdisciplinary team.

Recursion spends time and energy connecting every aspect of work to these values. They aren’t static, but regularly discussed and questioned because we make decisions rooted in those values in our day-to-day work.

More About Recursion

Recursion is a clinical stage TechBio company leading the space by decoding biology to industrialize drug discovery. Enabling its mission is the Recursion OS, a platform built across diverse technologies that continuously expands one of the world’s largest proprietary biological and chemical datasets. Recursion leverages sophisticated machine-learning algorithms to distill from its dataset a collection of trillions of searchable relationships across biology and chemistry unconstrained by human bias. By commanding massive experimental scale — up to millions of wet lab experiments weekly — and massive computational scale — owning and operating one of the most powerful supercomputers in the world, Recursion is uniting technology, biology and chemistry to advance the future of medicine.

Recursion is headquartered in Salt Lake City, where it is a founding member of BioHive, the Utah life sciences industry collective. Recursion also has offices in London, Toronto, Montreal and the San Francisco Bay Area. Learn more at www.Recursion.com, or connect on X (formerly Twitter) and LinkedIn.

Recursion is an Equal Opportunity Employer that values diversity and inclusion. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other characteristic protected under applicable federal, state, local, or provincial human rights legislation.

Recursion welcomes and encourages applications from people with disabilities. Accommodations are available on request for candidates taking part in all aspects of the selection process.