Senior Research Associate (Process Chemist)

Gilead Sciences; Edmonton; On-site; CAD 70,000 - 110,000; Full time

Job summary

An established industry player is seeking a Senior Research Associate I to join their dynamic team in Edmonton. This role involves applying chemical engineering fundamentals to support the manufacturing of active pharmaceutical ingredients. You will work collaboratively within a multi-disciplinary environment, tackling challenges in process development and optimization. Your contributions will directly impact the development of life-changing therapies, ensuring quality and efficiency in production. If you are passionate about making a difference in healthcare and thrive in a collaborative setting, this opportunity is perfect for you.

Qualifications

• Strong desire to work in multi-disciplinary teams and proactively solve problems.
• In-depth understanding of chemical engineering fundamentals and process development.
• Experience with purification techniques and statistical analysis.

Responsibilities

• Support manufacturing of active pharmaceutical ingredients through process development.
• Collaborate across functional areas to accomplish project goals.
• Ensure compliance with quality, safety, and environmental standards.

Skills

Chemical Engineering Fundamentals

Process Development

Analytical Techniques

Statistical Analysis

Collaboration Skills

Problem Solving

Education

MSc in Chemical Engineering

BSc in Chemical Engineering

Tools

HPLC

LCMS

NMR

SAS-JMP

DynoChem

CFD Simulation

Job description

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.

Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact.

We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.

Job Description

Gilead Sciences in Edmonton, Alberta, Canada is seeking a knowledgeable and motivated professional capable of working effectively in a multi-disciplinary team environment. The successful candidate will assume a full-time employment role in the capacity of Senior Research Associate I, Process Development in Gilead Alberta’s Manufacturing Science and Technology (MSAT) department.

Combining laboratory experimentation, with engineering calculations and modeling, the successful candidate supports manufacturing of active pharmaceutical ingredients (API) by applying chemical engineering fundamentals in process development, characterization, optimization, risk assessments, technology transfer, and scale-up/scale-down models.

Essential Duties and Job Functions:

• Demonstrates technical proficiency, scientific creativity, and collaboration skills in the research and development of API manufacturing processes.
• Acts as a process engineering subject matter expert for cross-functional teams and collaborates across functional areas including: process development, analytical operations, quality assurance, engineering and manufacturing to accomplish project goals.
• Applies chemical engineering knowledge to provide solutions to issues that are encountered during process development and manufacturing of clinical and commercial API.
• Completes equipment equivalency and equipment selection evaluations to guide process technology transfer to internal and external manufacturing sites.
• Follows established process engineering workflows and procedures to support process development, scale-up, and scale-down of unit operations.
• Effectively presents and discusses results, and draws conclusions independently. Provides regular updates (written and verbal) and proposes future research directions.
• Prepares clear and concise written work summaries, data analyses, and technical reports.
• Applies engineering modeling and simulations to support process development of manufacturing processes and enabling manufacturing technologies.
• Provides technical support for manufacturing processes performed under cGMP in laboratory manufacturing and large-scale manufacturing operations.
• Ensures that all experimentation is carried out in accordance with appropriate standard operating procedures (SOPs), maintaining quality, safety, and environmental standards.

Knowledge, Experience and Skills:

• Strong desire to work in multi-disciplinary teams, learn new skills and proactively solve problems.
• Excellent verbal and written communication skills and strong interpersonal collaboration skills.
• Must think critically and creatively and be able to work independently to determine appropriate resources for resolution of problems.
• In depth understanding of chemical engineering fundamentals.
• Experience in scale-up and scale-down of chemical process unit operations.
• Familiarity with statistical analysis to evaluate correlations, shifts and trends of chemical processes, and experience of Design of Experiments (DOE) is an asset.
• Familiarity with purification and analytical techniques, including HPLC, LCMS and NMR is an asset.
• Experience with kinetic studies or process analytical technologies (PAT) is an asset.
• Experience with continuous manufacturing is an asset.
• Experience with SAS-JMP, DynoChem, CFD simulation or other statistical analysis or simulation software is an asset.
• Familiarity with process validation and cGMP guidelines is an asset.

Minimum Qualifications:

• MSc in chemical engineering, chemistry, or related field and 0+ years of experience OR
• BSc in chemical engineering, chemistry or related field with 2+ years of process chemistry training in pharmaceutical industry

For Current Gilead Employees and Contractors:

Please apply via the Internal Career Opportunities portal in Workday.