Senior Principal Statistician

Johnson & Johnson; Toronto; Hybrid; CAD 124,000 - 213,000; Full time

Job summary

Johnson & Johnson in Toronto seeks a Senior Principal Statistician to lead statistical strategy across oncology drug discovery programs within Innovative Medicine Research & Development. This role drives quantitative decision-making, collaborates across multidisciplinary teams, and advances translational biomarker development.

The candidate will apply advanced modeling, AI-enabled workflows, and reproducible methods to inform target identification through candidate selection, contributing to

Qualifications

• PhD in Statistics, Biostatistics, Applied Statistics, Bioinformatics, Data Science, or related quantitative field with 6+ years of experience.
• Recognized expertise in statistical methods, experimental design, and quantitative decision-making.
• Track record of influencing scientific and portfolio decisions through quantitative evidence.
• Experience applying modeling, simulation, predictive analytics, and high-dimensional data analysis.
• Ability to translate statistical concepts into actionable insights for scientific and business audiences.
• Scientific leadership across multidisciplinary teams and collaborations.
• Proficiency in R and modern AI-enabled workflows; travel up to 10–15%.

Responsibilities

• Lead statistical strategy for priority oncology programs and shape decisions through quantitative evidence.
• Apply and advance statistical modeling, AI/ML, biomarker analytics, and decision frameworks to accelerate drug discovery.
• Drive experimental design, modeling, and data analysis across translational, preclinical, and high-dimensional studies.
• Forge partnerships across functions and external organizations to advance program objectives.
• Develop analytics capabilities and AI-enabled workflows with data science partners.
• Champion reproducible research, data integrity, statistical standards, and rigorous methods.
• Lead publications, presentations, and external collaborations advancing statistical methods.

Skills

Statistical methods

Experimental design

Quantitative decision-making

R

Education

PhD in Statistics

Tools

R

Job description

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function

Data Analytics & Computational Sciences

Job Sub Function

Biostatistics

Job Category

Scientific/Technology

All Job Posting Locations

Toronto, Ontario, Canada

Job Description

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for a Senior Principal Statistician in Toronto, Canada.

Remote work options may be considered on a case-by-case basis and if approved by the Company.

Please note that this role is also available across multiple countries and may be posted under different requisition numbers to comply with local requirements. While you are welcome to apply to any or all of the postings, we recommend focusing on the specific country(s) that align with your preferred location(s).

United States - Requisition Number: R-097788

Canada - Requisition Number: R-099269

Remember, whether you apply to one or all of these requisition numbers, your applications will be considered as a single submission.

Purpose:

We are seeking an outstanding Senior Principal Statistician to join our Discovery Oncology Statistics organization within Johnson & Johnson Innovative Medicine Research & Development. This scientific leadership role provides strategic statistical leadership across oncology drug discovery programs, representing statistics in key scientific and portfolio discussions and helping drive critical decisions from target identification through candidate selection and translational biomarker development.

This is an exciting opportunity to influence the future of cancer drug discovery by applying innovative statistical methodologies, machine learning, data science, and quantitative decision-making to some of the most exciting scientific questions in oncology. The successful candidate will collaborate across multidisciplinary research teams and contribute to innovation that directly impacts the advancement of transformational medicines for patients.

You will be responsible for:

• Lead statistical strategy for priority oncology programs and shape scientific and portfolio decisions through quantitative evidence.
• Apply and advance statistical modeling, AI/ML, biomarker analytics, and quantitative decision frameworks to accelerate drug discovery.
• Drive experimental design, modeling, and data analysis across translational, in vivo, combination, and high-dimensional studies.
• Forge partnerships across functions and external organizations to advance program objectives and quantitative decision-making.
• Develop analytics capabilities, AI-enabled workflows, statistical methods, and decision-support tools with data science partners.
• Champion reproducible research, data integrity, statistical standards, and methodological rigor.
• Lead publications, scientific presentations, and external collaborations that advance statistical methods and scientific practice.

Qualifications / Requirements

Education

• Minimum of a PhD in Statistics, Biostatistics, Applied Statistics, Bioinformatics, Data Science, or a related quantitative discipline with a minimum of 6 years of relevant experience in pharmaceutical, biotechnology, or healthcare research is required.

Required

• Recognized expertise in statistical methods, experimental design, and quantitative decision-making for drug discovery and translational research.
• Track record of influencing scientific and portfolio decisions through quantitative evidence.
• Experience applying modeling, simulation, predictive analytics, and high-dimensional data analysis.
• Ability to translate statistical concepts into actionable insights for scientific and business audiences.
• Scientific leadership of complex programs, shaping scientific strategy and decision-making across multidisciplinary teams.
• Proficiency in R and modern computational and AI-enabled workflows.
• Travel: Up to 10-15% domestic and international travel may be required.

Preferred

• Recognized expertise in oncology drug discovery, translational research, and biomarker-driven decision-making.
• Experience applying machine learning, artificial intelligence, and advanced analytical methods to biomedical and drug discovery datasets.
• Experience with genomic, transcriptomic, proteomic, imaging, spatial biology, or other multi-omics datasets.
• Previous people leadership, mentoring, scientific coaching, or matrix leadership experience.
• Experience leading external collaborations, academic partnerships, scientific consortia, or industry working groups, with a demonstrated record of external scientific impact.

Additional Description for Pay Transparency

124,000 - 212,750 CAD

• Under current guidelines, this position is eligible for a discretionary performance bonus.
• The Company uses Artificial Intelligence in its assessment of applicants.
• This job posting is for an existing position.