About the Role
Our client, a prominent pharmaceutical research company, is seeking a highly skilled Senior Organic Chemist specializing in Synthesis to join their dedicated research and development team in Kimberley. This role is critical for designing and executing complex synthetic routes to novel chemical compounds with therapeutic potential. You will lead challenging synthesis projects, troubleshoot synthetic challenges, and contribute to the discovery pipeline of new medicines. The ideal candidate will possess a deep understanding of modern organic chemistry methodologies, strong practical laboratory skills, and a proven track record in multi-step synthesis. Join our innovative team in Kimberley and play a key role in bringing life-changing therapies closer to reality.
Key Responsibilities
- Design and execute multi-step synthetic routes for complex organic molecules, including active pharmaceutical ingredients (APIs).
- Develop and optimize synthetic procedures to ensure efficiency, scalability, and purity.
- Utilize a wide range of modern organic chemistry techniques and instrumentation.
- Characterize synthesized compounds using advanced analytical methods (e.g., NMR, MS, HPLC, IR).
- Troubleshoot challenging synthetic reactions and identify creative solutions.
- Collaborate with medicinal chemists and biologists to support drug discovery programs.
- Mentor junior chemists, providing guidance on synthetic strategies and laboratory techniques.
- Maintain detailed and accurate laboratory notebooks and records.
- Contribute to the preparation of research reports, publications, and patent applications.
- Ensure adherence to all laboratory safety regulations and protocols.
Requirements
- Ph.D. in Organic Chemistry or a closely related field.
- A minimum of 5 years of post-doctoral or industrial experience in synthetic organic chemistry.
- Proven expertise in designing and executing complex, multi-step organic syntheses.
- Hands-on experience with a broad spectrum of organic reactions and purification techniques.
- Proficiency in modern spectroscopic and chromatographic analytical methods (NMR, MS, HPLC, GC).
- Strong problem-solving abilities and excellent attention to detail.
- Demonstrated ability to lead projects and mentor junior scientists.
- Excellent written and verbal communication skills.
- Ability to work effectively both independently and as part of a collaborative team.
- Familiarity with structure-based drug design principles is a plus.
Benefits
- Competitive salary commensurate with experience and qualifications.
- Comprehensive health, dental, and vision insurance.
- Generous annual leave and paid holidays.
- Opportunities for professional development and continuing education.
- Access to state-of-the-art synthetic and analytical laboratory facilities.
- Collaborative and scientifically stimulating work environment.
- Retirement savings plan with employer match.
- Relocation assistance available for qualified candidates moving to Kimberley.
- Opportunity to contribute to the development of innovative pharmaceutical products.