Senior Organic Chemist - Synthesis

Placements24

Kimberley

On-site

CAD 120,000 - 180,000

Full time

5 days ago
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Benefits offered by this job

Health insurance
Dental insurance
Vision insurance
Annual leave
Paid holidays
Professional development
Lab facilities access
Relocation assistance

Job summary

Placements24 in Kimberley, Canada, seeks a Senior Organic Chemist (Synthesis) to lead multi-step routes for complex APIs. You will develop procedures, scale experiments, and apply NMR/MS/HPLC/GC analyses to ensure purity and yield.

The role emphasizes mentoring junior scientists and collaboration with medicinal chemists in a dynamic R&D environment. You will contribute to publications and patents, maintain meticulous notebooks, and uphold safety standards while advancing therapeutic discovery in

Qualifications

  • Ph.D. in Organic Chemistry or closely related field is required.
  • Minimum 5 years post-doctoral or industrial experience in synthetic organic chemistry.
  • Proven expertise in designing and executing complex multi-step organic syntheses.
  • Hands-on experience with a broad spectrum of organic reactions and purification techniques.
  • Proficiency in modern spectroscopic and chromatographic methods (NMR, MS, HPLC, GC).
  • Demonstrated leadership and mentoring abilities with strong communication skills.

Responsibilities

  • Design and execute multi-step synthetic routes for complex organic molecules, including APIs.
  • Develop and optimize synthetic procedures for efficiency, scalability, and purity.
  • Utilize a wide range of modern organic chemistry techniques and instrumentation.
  • Characterize synthesized compounds using advanced analytical methods (NMR, MS, HPLC, GC).
  • Troubleshoot challenging reactions and identify creative solutions.
  • Collaborate with medicinal chemists and biologists to support drug discovery programs.
  • Mentor junior chemists and guide laboratory techniques and strategies.
  • Maintain detailed laboratory notebooks and records; contribute to reports and patents.
  • Ensure adherence to safety regulations and best practices.

Skills

Multi-step synthesis design
Project leadership
Analytical techniques
Problem solving
Mentoring/leadership
Scientific communication
Team collaboration
Structure-based drug design awareness

Education

Ph.D. in Organic Chemistry

Tools

NMR
MS
HPLC
GC

Job description

About the Role

Our client, a prominent pharmaceutical research company, is seeking a highly skilled Senior Organic Chemist specializing in Synthesis to join their dedicated research and development team in Kimberley. This role is critical for designing and executing complex synthetic routes to novel chemical compounds with therapeutic potential. You will lead challenging synthesis projects, troubleshoot synthetic challenges, and contribute to the discovery pipeline of new medicines. The ideal candidate will possess a deep understanding of modern organic chemistry methodologies, strong practical laboratory skills, and a proven track record in multi-step synthesis. Join our innovative team in Kimberley and play a key role in bringing life-changing therapies closer to reality.

Key Responsibilities
  • Design and execute multi-step synthetic routes for complex organic molecules, including active pharmaceutical ingredients (APIs).
  • Develop and optimize synthetic procedures to ensure efficiency, scalability, and purity.
  • Utilize a wide range of modern organic chemistry techniques and instrumentation.
  • Characterize synthesized compounds using advanced analytical methods (e.g., NMR, MS, HPLC, IR).
  • Troubleshoot challenging synthetic reactions and identify creative solutions.
  • Collaborate with medicinal chemists and biologists to support drug discovery programs.
  • Mentor junior chemists, providing guidance on synthetic strategies and laboratory techniques.
  • Maintain detailed and accurate laboratory notebooks and records.
  • Contribute to the preparation of research reports, publications, and patent applications.
  • Ensure adherence to all laboratory safety regulations and protocols.
Requirements
  • Ph.D. in Organic Chemistry or a closely related field.
  • A minimum of 5 years of post-doctoral or industrial experience in synthetic organic chemistry.
  • Proven expertise in designing and executing complex, multi-step organic syntheses.
  • Hands-on experience with a broad spectrum of organic reactions and purification techniques.
  • Proficiency in modern spectroscopic and chromatographic analytical methods (NMR, MS, HPLC, GC).
  • Strong problem-solving abilities and excellent attention to detail.
  • Demonstrated ability to lead projects and mentor junior scientists.
  • Excellent written and verbal communication skills.
  • Ability to work effectively both independently and as part of a collaborative team.
  • Familiarity with structure-based drug design principles is a plus.
Benefits
  • Competitive salary commensurate with experience and qualifications.
  • Comprehensive health, dental, and vision insurance.
  • Generous annual leave and paid holidays.
  • Opportunities for professional development and continuing education.
  • Access to state-of-the-art synthetic and analytical laboratory facilities.
  • Collaborative and scientifically stimulating work environment.
  • Retirement savings plan with employer match.
  • Relocation assistance available for qualified candidates moving to Kimberley.
  • Opportunity to contribute to the development of innovative pharmaceutical products.
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