Scientist, Process Development

STEMCELL Technologies; Burnaby; On-site; CAD 86,000 - 129,000; Full time

Job summary

STEMCELL Technologies seeks a Scientist to lead upstream process development for protein production and scale-up in a cGMP environment. You will collaborate across R&D, QA, QC, and CDMOs to transfer processes into manufacturing and drive robust, cost-efficient workflows for biologics.

The role requires advanced degree experience with mammalian cell culture, DoE/QbD, and technology transfer expertise, delivering reliable processes and continuous improvement across sites.

Qualifications

• Bachelor's with 6+ years, Masters with 4-8 years or PhD with 2-5 years of relevant experience
• Deep understanding and practical expertise in upstream protein production process development, including optimization and scale-up using mammalian cell lines in cGMP environments
• Experience with process scale-up/down models and concepts, Design of Experiments (DoE), statistical methods, and Quality by Design (QbD) principles
• Experience in technology transfer to manufacturing facilities, including CDMOs

Responsibilities

• Act as a SME, providing technical recommendations to cross-functional project teams for upstream process development supporting cGMP protein manufacturing
• Oversee upstream development activities, including design, risk assessment, development, and transfer of safe, efficient, and robust processes
• Analyze experimental data, presenting conclusions and findings to cross-functional teams, and develop and transfer SOPs into manufacturing
• Lead and participate in non-conformance root cause investigations, supporting the execution of corrective and preventative actions (CAPAs)
• Collaborate internally with R&D, Quality Control, Quality Assurance & Regulatory teams, and externally with contract development and manufacturing organizations (CDMOs)

Skills

Upstream process development

Design of Experiments

Quality by Design

Scale-up (mammalian cells)

Education

Bachelors with 6+ years

Masters with 4-8 years

PhD with 2-5 years

Job description

Job Description Summary

Do you enjoy solving complex problems, building relationships with collaborators, and continuously learning in a fast-paced and innovative environment? As a member of the Process Development, Biologics team you will work alongside experienced Engineers, Associates, and Scientists who collaborate closely on delivering robust, cost efficient, and innovative manufacturing processes for biologic products meeting appropriate regulatory and current good manufacturing practices (cGMP) requirements.

As a Scientist, you will lead and execute upstream process development for protein production, from experimental design through scale-up and technology transfer. Acting as a subject matter expert (SME), you will collaborate across cross-functional teams and help establish new workflows for proteins with end uses in Ancillary Material at STEMCELL!

Job Description

Duties and Responsibilities

• Act as a SME, providing technical recommendations to cross-functional project teams for upstream process development supporting cGMP protein manufacturing
• Oversee upstream development activities, including design, risk assessment, development, and transfer of safe, efficient, and robust processes
• Analyze experimental data, presenting conclusions and findings to cross-functional teams, and develop and transfer SOPs into manufacturing
• Lead and participate in non-conformance root cause investigations, supporting the execution of corrective and preventative actions (CAPAs)
• Collaborate internally with R&D, Quality Control, Quality Assurance & Regulatory teams, and externally with contract development and manufacturing organizations (CDMOs)

Knowledge And Qualifications

• Bachelors with 6+ years, Masters with 4-8 years or PhD with 2-5 years of relevant experience
• Deep understanding and practical expertise in upstream protein production process development, including optimization and scale-up using mammalian cell lines in cGMP environments
• Experience with process scale-up/down models and concepts, Design of Experiments (DoE), statistical methods, and Quality by Design (QbD) principles
• Experience in technology transfer to manufacturing facilities, including CDMOs

STEMCELL Technologies is a privately owned, Vancouver-based biotechnology company that helps power leading-edge life science research around the world. Driven by our love of science and passion for quality, we are a company of Scientists Helping Scientists—standing by our customers to provide the outstanding products, technical support, and training they need to advance their research. Scientists performing stem cell, immunology, cancer, regenerative medicine, and cellular therapy research are among those who rely on our cell culture media, cell separation products, instruments, accessory products, and services. Through our many regional offices, as well as our distribution centers in Vancouver, Seattle, Grenoble, and Singapore, we deliver our innovative, specialized products to more than 100 countries. With over 1,800 employees globally, most with scientific or engineering degrees, STEMCELL is proud to be the largest biotechnology employer in Canada.

This is an opportunity to work with highly motivated colleagues in a science-oriented, creative, and dynamic environment. We offer a competitive salary, excellent benefits, and meaningful career development opportunities.

STEMCELL is well recognized for exceptional leadership and business practices. We are one of Canada’s Best Managed Companies and operate an ISO 14001-certified environmental management system to measure and reduce our environmental impact.

As an equal opportunity employer, STEMCELL is dedicated to ensuring that every employee feels safe, valued, and respected for who they are. We know that scientific progress and innovation occur when diverse, creative minds come together and we are committed to nurturing a culture of inclusivity and belonging. STEMCELL enforces a zero-tolerance policy for any form of discrimination. Selection decisions are solely based on job-related factors.

The annual salary for this job ranges from:

$85,700.00 - $128,500.00

STEMCELL determines an individual’s pay within the range based on multiple factors including experience, education, job-related skills, and equity within the team or organization. For jobs that are eligible for sales incentives, the range noted above is inclusive of target incentives; actual incentives are based on individual performance results in accordance with company policy. In addition to base salary, STEMCELL offers a comprehensive total rewards package including health benefits, retirement savings, and more.