Scientist, Biomolecular Interactions (12 Month Contract)

Biopharma Careers; Burnaby; On-site; CAD 109,000 - 148,000; Full time

Job summary

Amgen BC in Burnaby, BC, invites a Scientist, Biomolecular Interactions to join the In Vitro Pharmacology affinity team for discovery and characterization of novel therapeutic antibodies. This 12-month contract offers exposure to high-throughput and bespoke biophysical assays and collaboration with skilled scientists.

The successful candidate will develop and optimize screening assays (SPR/BLI, Biacore) with data analysis using PRISM, R/Python, and ELN reporting, contributing to a

Qualifications

• Doctorate or equivalent with relevant experience.
• Master's degree with 3+ years related experience.
• Bachelor's degree with 5+ years related experience.
• Experience with SPR/BLI and Biacore instrumentation.
• Experience with mammalian cell culture and transfection is a plus.

Responsibilities

• Conduct routine and novel affinity/kinetic characterization screens on relevant platforms (Carterra, Octet, Biacore, KinExA).
• Instrument housekeeping, reagent ordering, troubleshooting.
• Data summarizing and reporting (ELN, Screener, Benchling).

Skills

Collaboration

Analytical mindset

DoE tasks

Multitasking

Education

Doctorate degree

Master's degree + 3 years experience

Bachelor's degree + 5 years experience

Tools

Biacore

KinExA

PRISM

R/Python

Job description

Career Category

Scientific

Job Description

Join Amgen's Mission of Serving Patients

At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission, to serve patients living with serious illnesses, drives all that we do.

Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas - Oncology, Inflammation, General Medicine, and Rare Disease - we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Role: Scientist, Biomolecular Interactions (12 Month Contract)

Reports to: Principal Scientist

Location: Burnaby, BC

What you will do

Let's do this. Let's change the world. In this vital role, you will join Amgen BC's affinity team in In Vitro Pharmacology group to discover novel therapeutic antibodies.

Our small team specializes in designing and conducting both high throughput and smaller, custom biophysical screening assays to rank and characterize both discovery and later stage large molecule therapeutic programs. The individual will join a team of dedicated scientists to discover and characterize molecules that have the potential to help patients in need. A well-suited applicant will have great laboratory skills, a strong analytical mindset, deep scientific curiosity, and a can-do attitude. The successful candidate will be responsible for the development, optimization, and implementation of various biophysical based screening assays for novel therapeutic candidates with guidance from the lead Scientist.

Essential Functions

• Conduct routine and novel affinity/kinetic characterization screens on all relevant platforms (Carterra, Octet, Biacore, KinExA), including custom assays and assay development
• Instrument housekeeping, reagent ordering, troubleshooting
• Data summarizing and reporting (ELN, Screener, Benchling, slide decks), timely documentation

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The highly motivated professional we seek is a collaborative team player with these qualifications.

Basic Qualifications

• Doctorate degree
• OR
• Master's degree & 3 years of related experience
• OR
• Bachelor's degree & 5 years of directly related experience

Preferred Qualifications

• Deep understanding of molecular binding interaction theory (SPR, BLI), hands on experience and instrumentation nuances – specifically Biacore, ideally 1K/8K series, KinExA experience strongly preferred
• A good understanding of protein chemistry and/or a general biochemistry background; antibody experience desired
• Experience with mammalian cell culture (CHO, HEK) and transfection; on cell affinity assays or FACS is preferred
• Experience with data analysis using PRISM, Codex and custom R/Python is an asset
• A keen eye and a strong analytical mindset, with an interest and aptitude for DoE tasks (e.g. assay dev/troubleshooting) and data analysis and interpretation
• Ability to multitask and stay organized in the face of shifting priorities without losing focus

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well‑being.

Amgen is proud to have been recognized as one of LinkedIn Top 25 Companies in Canada for career growth.

In addition to the base salary, Amgen offers competitive and comprehensive Total Rewards Plans that are aligned with local industry standards.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Salary Range

109,254.75 CAD - 147,815.25 CAD