Transpharmation is a dynamic preclinical contract research organization that specializes in high-quality, translational drug discovery services. The company provides a friendly and team-oriented work atmosphere as well as competitive wages and benefits.
The Research Technician II (“RT II”) will have a solid understanding of each individual’s roles and responsibilities within the company and within research studies. The RT II will have a clear understanding of and be able to perform a majority of the procedures at Transpharmation within the Rodent Department. The RT II will demonstrate a clear understanding of the complexities of a research trial and be able to efficiently follow study protocols, with continued guidance from the Study Director/Coordinator.
Duties And Responsibilities
- Assisting and performing assigned in vivostudy procedures in the Rodent Pharmacodynamic Department
- Recording and documenting experimental details with a high level of integrity, ethics and accuracy
- Assisting in the preparation of data summary reports, study related data entry, Quality Control
- Performing study-related husbandry duties to ensure proper animal care practices are adhered to and are according to CCAC guidelines and facility SOPs
- Working within a team to ensure that projects are successfully conducted and completed to a high level of quality and scientific competence
- Participating in the maintenance of an adequate inventory of supplies
- Assisting the Rodent Department Manager in the maintenance and operation of animal facility and husbandry in accordance with CCAC guidelines and Animals for Research Act
- Participating in internal working groups (e.g., animal care committee, health and safety, etc.)
- Explaining techniques to new employees and visitors
- Leading rodent operant training/testing
- Other duties as assigned
Duties Associated With The RTII Role
- Operate centrifuges and perform advanced blood separation
- Drug administrations (SC, IM, IP, IV, oral, interdermal, etc.)
- Survival blood collection (saphenous, tail snip, submandibular, catheter, etc.)
- Terminal blood collection, tissue/organ extraction and weighing
- Anaesthesia/Analgesia
- Euthanasia
- Restrain animals for procedures as needed
Seizure Testing
- Perform seizure testing from start to end independently, including but not limited to:
- MES
- 6Hz
- Corneal Kindling
- Amygdala Kindling
Pain Testing
- Perform pain testing from start to end independently (von Frey, acetone drop, tail flick, formalin, etc.)
Behavioral Testing
- Prepare rooms for testing
- Ability to operate test apparatus for behavioral and cognitive testing (LMA, rotorod, grip strength, body temperature, watermaze, etc.)
- Daily observations (health observations for safety studies)
Operant Testing
- Ability to lead operant training
Data Management
- Ability to create basic graphs from experimental results
- Understand basic data analysis (means, standard error, median, interquartile)
- Train staff on various procedures as appropriate
- Any other duties as deemed necessary
Knowledge And Skills
- Veterinary diploma or B.Sc. degree in a relevant field (e.g., Pharmacology, Pharmacokinetics, Veterinary Sciences, Biochemistry) and/or relevant equivalent with at least 2 years of direct experience
- CALAS certification encouraged
- Experience as a Research Technician for at least 1 year or relevant experience
- Experience within a laboratory environment
- Experience handling confidential laboratory and scientific data and samples
- Experience executing administrative strategies
- Proven organizational skills and attention to details
- Demonstrated ability to communicate effectively orally and in writing, with staff and the public
Job Type: Full-Time
(Weekend availability required)
Friday - Monday shift
Flexible Language Requirement
Education
- Bachelor's Degree (preferred)
Experience
- rodent handling: 1 year (required)
Work Location: In person