Principal Clinical Scientist

Alignerr Corp.; Montreal (administrative region); Remote; CAD 83,000 - 165,000; Full time

Job summary

Alignerr is seeking a Principal Clinical Scientist (AI Training) to lead design and review of clinical trial protocols used to generate regulator-ready AI training data. This remote, hourly contract role leverages decades of clinical trial expertise to ensure scientific and regulatory integrity in AI systems.

Ideal candidates have senior-level experience in clinical trial design and data interpretation for major regulators, with a strong background in biostatistics and translational science.

Qualifications

• Senior-level clinical scientist with hands-on experience designing trial protocols for regulatory submission.
• Deep expertise interpreting clinical data for major regulatory agencies (FDA, EMA, or equivalent).
• Strong grounding in clinical research methodology and biostatistics.

Responsibilities

• Design and critically review clinical trial protocols used to generate high-quality, regulator-ready AI training datasets.
• Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance.
• Evaluate AI-generated clinical analyses for scientific soundness and alignment with regulatory expectations (FDA/EMA or equivalent).
• Provide expert feedback that shapes how AI models reason about trial data, endpoints, and outcomes.
• Help establish quality standards for clinical evidence used in AI research workflows.

Skills

Trial design

Regulatory knowledge

Biostatistics

Clinical data interpretation

Education

PhD in life sciences

Tools

AI tools

Job description

Principal Clinical Scientist (AI Training)

About The Role

What if your decades of clinical trial expertise could directly influence how AI reasons about medical evidence, regulatory data, and patient outcomes? We're looking for a Principal Clinical Scientist to bring senior-level rigor to the frontier of AI development — ensuring the clinical knowledge embedded in next-generation AI systems meets the highest standards of scientific and regulatory integrity.

This is a fully remote, flexible contract role designed for experienced clinical scientists who want to do meaningful work on their own schedule. No AI background required — your deep domain expertise is what matters.

• Organization: Alignerr
• Type: Hourly Contract
• Location: Remote
• Commitment: 10–40 hours/week

What You'll Do

• Design and critically review clinical trial protocols used to generate high-quality, regulator-ready AI training datasets
• Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance
• Evaluate AI-generated clinical analyses for scientific soundness and alignment with FDA, EMA, or equivalent regulatory expectations
• Provide expert feedback that directly shapes how AI models reason about clinical trial data, endpoints, and outcomes
• Help establish quality standards for clinical evidence used in cutting-edge AI research workflows

Who You Are

• Senior-level clinical scientist with hands‑on experience designing trial protocols for regulatory submission
• Deep expertise interpreting clinical data for major regulatory agencies (FDA, EMA, or equivalent)
• Strong grounding in clinical research methodology, biostatistics, or translational science
• Naturally rigorous and detail‑oriented — you hold clinical evidence to the highest standards
• Comfortable working independently and asynchronously in a remote environment

Nice to Have

• Prior experience with data annotation, data quality review, or evaluation frameworks
• Background in clinical pharmacology, oncology, rare disease, or other specialized therapeutic areas
• Familiarity with AI tools or emerging applications of machine learning in clinical research

Why Join Us

• Work directly on frontier AI systems shaping the future of clinical and biomedical research
• Influence how AI understands, evaluates, and communicates real-world clinical evidence
• Fully remote and flexible — work when and where it suits you
• Freelance autonomy with the structure of meaningful, expert‑level work
• Collaborate with world‑leading AI research teams and labs
• Potential for ongoing work and contract extension as new projects launch