Principal Bioinformatics Software Engineer

F. Hoffmann-La Roche Gruppe; Mississauga; On-site; CAD 85,000 - 120,000; Full time

Job summary

A leading company in healthcare innovation seeks a Bioinformatics Engineer to design and develop high-performance algorithms for Next-Generation Sequencing (NGS) data analysis. This role involves collaboration with cross-functional teams and technical mentorship of junior engineers, contributing to impactful healthcare solutions. Candidates should hold a Master’s degree and possess extensive bioinformatics experience, particularly with programming languages and tools necessary for bioinformatics workflows.

Qualifications

• Over 6 years of experience in Bioinformatics.
• Strong proficiency in programming languages such as Python, Java, and/or C++.
• Hands-on experience with workflow management systems.

Responsibilities

• Design, develop, and implement bioinformatics algorithms and pipelines for analyzing NGS data.
• Collaborate with biologists and data scientists to meet specific requirements.
• Create documentation for algorithms and workflows, facilitating knowledge transfer.

Skills

Python

Java

C++

bioinformatics tools and libraries

problem-solving

communication

Education

Master's degree in Computational Biology, Bioinformatics, Computer Science, or Statistics

Tools

Docker

Nextflow

Github

CI/CD

AWS

Google Cloud

Job description

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

A healthier future It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.

Your Opportunity

• Design, develop, and implement high-performance bioinformatics algorithms and pipelines for analyzing NGS data, including read processing, alignment, variant calling, quality control and reporting.

• Conduct all aspects of algorithm and pipeline development work including design, implementation, testing, verification, and continuous optimization to ensure accuracy, efficiency and scalability.

• Collaborate with biologists, data scientists, and other software engineers to understand the specific requirements, constraints and other Roche systems to ensure seamless communication and integration

• Support internal users, evaluate use cases, propose, evaluate and implement solutions

• Create documentation for algorithms and workflows, visualization of data and present across teams to facilitate knowledge transfer and ensure reproducibility.

• Mentor and provide technical guidance to junior engineers, fostering a culture of innovation and learning within the team.

Who you are

• You have a Master or higher degree in Computational Biology, Bioinformatics, Computer Science, Statistics or other quantitative fields.

• You have over 6 years of experience in Bioinformatics

• Strong proficiency in programming languages such as Python, Java, and/or C++ with proven experience in developing bioinformatics algorithms for NGS data analysis.

• Proficiency in bioinformatics tools and libraries.

• Hands-on experience with workflow management systems such as Nextflow, WDL, etc., and proficiency with microservices architecture including the use of Docker and container orchestration.

• Excellent problem-solving skills, attention to detail, and effective communication and teamwork abilities.

Preferred:

• Experience with software development tools such as Github, PyTest, CI/CD etc.

• Experience with cloud infrastructure AWS, Google Cloud is a plus

• experience with GPU programming (CUDA, OpenCL) and optimizing bioinformatics workflows for GPU acceleration.

Relocation benefits are not available for this position.

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Roche is an Equal Opportunity Employer.