Postdoctoral Researcher - Synthetic Medicinal Chemistry

University Health Network; Toronto; On-site; CAD 55,000 - 71,000; Full time

Benefits offered by this job

HOOPP pension plan

Transit access

Flexible work environment

Development opportunities

Job summary

The Weaver Medicinal Chemistry Research Lab at the Krembil Research Institute within University Health Network seeks a Postdoctoral Researcher in Medicinal Synthetic Chemistry to design and synthesize new small molecule drug platforms for neurodegenerative disease research. You will work closely with computational chemists and biologists to advance therapeutic candidates.

This role involves multi-step synthesis, data management, and collaboration in a dynamic, interdisciplinary team pursuing

Qualifications

• PhD in synthetic organic chemistry or synthetic medicinal chemistry obtained within the previous 5 years.
• Significant experience and expertise in synthetic organic chemistry.
• Solid documentation and organizational skills.
• Ability to collaborate with scientists from other disciplines integrating data from non-chemistry sources.
• Must be able to work in a large, diverse research group.

Responsibilities

• Conduct multi-step synthesis of small molecules using state of the art synthetic chemistry techniques.
• Maintain lab notebook and data records.
• Assist in preparation of grant applications and publications.
• Assist and supervise undergraduate and graduate students, as required.
• Follow all safety protocols.
• Follow process for ordering, receiving and maintaining lab supplies.
• Update and use chemical inventory, as required.

Skills

Collaboration across disciplines

Documentation & organization

Multi-disciplinary teamwork

Lab teamwork

Education

PhD in synthetic organic chemistry or related field

Job description

UHN is Canada’s #1 hospital and the world’s #1 publicly funded hospital. With 10 sites and more than 44,000 TeamUHN members, UHN consists of Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre, Toronto Rehabilitation Institute, The Michener Institute of Education and West Park Healthcare Centre. As Canada's top research hospital, the scope of biomedical research and complexity of cases at UHN have made it a national and international source for discovery, education and patient care. UHN has the largest hospital-based research program in Canada, with major research in neurosciences, cardiology, transplantation, oncology, surgical innovation, infectious diseases, genomic medicine and rehabilitation medicine. UHN is a research hospital affiliated with the University of Toronto.

UHN’s vision is to build A Healthier World and it’s only because of the talented and dedicated people who work here that we are continually bringing that vision closer to reality.

www.uhn.ca

Union: Non-Union
Number of vacancies: 1
New or Replacement Position: New
Site: Krembil Discovery Tower
Department:Krembil Brain Institute
Reports to:Senior Scientist
Salary Range:$54,902 to $71,372 per annum
Hours: 37.5 hours per week
Shifts: Day
Status: Temporary Full-time
Closing Date: October 16, 2026

Position Summary

The Weaver Medicinal Chemistry Research Lab at the Krembil Research Institute is a multi-disciplinary research group consisting of computational and synthetic chemists, biochemists, molecular biologists, and behavioural neuroscientists. Our goal is to design and develop new therapeutic molecules for the treatment of neurodegenerative disorders such as Alzheimer’s Disease. As a Postdoctoral Researcher in Medicinal Synthetic Chemistry you will help design and synthesize new chemical entity small molecules as putative drug platforms. You will work closely with our computational chemists and biologists.

Duties

• Conduct multi-step synthesis of small molecules using state of the art synthetic chemistry techniques
• Maintain lab book and data records
• Assist in preparation of grant applications and publications
• Assist and supervise undergraduate and graduate students, as required
• Follow all safety protocols
• Followprocess for ordering, receiving and maintaining lab supplies
• Updateand usechemical inventory, as required

Required Qualifications

• PhD in synthetic organic chemistry or synthetic medicinal chemistry obtained within the previous 5 years
• Significant experience and expertise in synthetic organic chemistry
• Solid documentation and organizational skills
• Ability to collaborate with scientists from other disciplines integrating data from non-chemistry sources
• Must be able to work in a large, diverse research group

Why join UHN?

In addition to working alongside some of the most talented and inspiring healthcare professionals in the world, UHN offers a wide range of benefits, programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor, allowing you to find value where it matters most to you, now and throughout your career at UHN.

• Competitive offer packages
• Government organization and a member of the Healthcare of Ontario Pension Plan (HOOPP https://hoopp.com/)
• Close access to Transit and UHN shuttle service
• A flexible work environment
• Opportunities for development and promotions within a large organization
• Additional perks (multiple corporate discounts including: travel, restaurants, parking, phone plans, auto insurance discounts, on-site gyms, etc.)

Current UHN employees must have successfully completed their probationary period, have a good employee record along with satisfactory attendance in accordance with UHN's attendance management program, to be eligible for consideration.

Please be advised that a Criminal Record Check may be required of the successful candidate. Should it be determined that any information provided by a candidate be misleading, inaccurate or incorrect, UHN reserves the right to discontinue with the consideration of their application.

UHN is an equal opportunity employer committed to an inclusive recruitment process and workplace. Requests for accommodation can be made at any stage of the recruitment process. Applicants need to make their requirements known.