Local Trial Manager - Oncology - Canada - Home Based

Pharmaceutical Research Associates, Inc; Canada; Remote; CAD 70,000 - 90,000; Full time

Job summary

A leading clinical research organization in Canada seeks a Local Trial Manager to oversee end-to-end trial delivery. Responsibilities include managing local vendors, ensuring trial excellence, and collaborating with local teams. Candidates should have a BA/BS degree in a health or science-related field and at least 2 years of trial management experience, particularly in oncology. This position offers various benefits and emphasizes diversity and inclusion.

Benefits

Annual leave entitlements

Health insurance options

Retirement planning

Life assurance

Gym discounts

Qualifications

• Minimum 2 years of local trial management experience.
• Experience with start-up, database locks, and data cleaning preferred.
• Legally authorized to work in Canada.

Responsibilities

• Manage Central IRB and local vendors.
• Execute local milestones from feasibility to study close-out.
• Ensure inspection readiness and conduct AQR.

Skills

Local trial management experience

Oncology trial management

Knowledge of ICH-GCP

Communication skills

Education

BA/BS in health or science-related field

Tools

Clinical trial management software

Job description

Overview

As a Local Trial Manager, you will join the world’s largest & most comprehensive clinical research organization, powered by healthcare intelligence.

Responsibilities

What you will be doing:

The L-LTM role is responsible for ensuring top-quality end-to-end trial delivery at a country level, managing the consistency of Local Trial Management duties and processes. The L-LTM serves as the country-level single point of contact on the study for internal partners. While tasks may be delegated to other LTMs or roles, the L-LTM remains accountable for their successful completion.

The L-LTM will oversee the following throughout the study:

• Managing Central IRB and local vendors (e.g., Greenphire, Drug Destruction services), including setup of vendor purchase orders, invoice review, approval, and change-orders.
• Executing local milestones from feasibility to study close-out.
• Resourcing country-level roles, supporting transitions in collaboration with the study Functional Manager (FM).
• Ensuring inspection readiness and conducting AQR at the country level.
• Collaborating with Local Trial Managers, Lead Site Managers, Site Managers, Clinical Trial Associates, and Site Contract Managers to outline responsibilities and provide support and training as needed.
• Communicating effectively with Clinical Trial Managers, Clinical Operations, and the Global Trial Leader to oversee trial excellence.
• Holding ad hoc meetings during any study phase to address unexpected issues impacting deliverables.
• Partnering with the study FM to provide updates, discuss hurdles, timelines, resources, risks, and assist with documentation like storyboards, lessons learned, and metrics.

Qualifications

What you need to have

• BA/BS degree, preferably in a health or science-related field.
• At least 2 years of local trial management experience.
• Experience with start-up, database locks, and data cleaning is preferred.
• Oncology trial management experience is required; early development experience is a plus.
• Strong knowledge of ICH-GCP, company SOPs, local laws (e.g., Canadian regulations), REB submissions, and protocol-specific procedures.
• Proficient in relevant software and company systems.
• Willingness to travel, including occasional overnight stays.
• Fluent in the local language and English, with good communication skills.
• Legally authorized to work in Canada; no sponsorship needed now or in the future.

What ICON can offer you: Our success depends on our people. We focus on building a diverse culture that rewards performance and nurtures talent. Benefits include:

• Annual leave entitlements
• Health insurance options
• Retirement planning
• Global Employee Assistance Programme (TELUS Health)
• Life assurance
• Optional benefits like childcare vouchers, bike schemes, gym discounts, and more.

Visit our careers website for more: https://careers.iconplc.com/benefits

ICON values inclusion and belonging, providing an accessible environment for all candidates. We are committed to equal opportunity employment and reasonable accommodations for applicants with disabilities. For assistance, contact us through the provided link.

We encourage you to apply even if you’re unsure whether you meet all requirements—your skills may be a great fit for this or other roles at ICON.