Graduate Student in Engineering for Protein Therapeutics Device Development

University of Toronto; Toronto; On-site; CAD 40,000 - 70,000; Full time

Job summary

An established industry player is seeking a passionate graduate student to join a pioneering team in engineering for protein therapeutics device development. This role offers a unique opportunity to work on cutting-edge projects that merge engineering with synthetic biology, focusing on the creation of innovative devices for protein production. You'll gain hands-on experience in device prototyping, automation, and bioprocess integration while collaborating with a diverse team of experts. If you're eager to make a meaningful impact in biomanufacturing and contribute to advancing healthcare solutions, this position is perfect for you.

Qualifications

• Strong engineering background in Mechanical, Electrical, or Biomedical fields.
• Experience in device design, CAD software, and prototyping.
• Proficiency in programming for device control and automation.

Responsibilities

• Design and prototype fluidic devices for protein synthesis.
• Integrate temperature control and real-time monitoring systems.
• Collaborate with a multidisciplinary team for project development.

Skills

Mechanical Engineering

Electrical Engineering

Biomedical Engineering

Mechatronics

Device Design

CAD Software (Fusion 360)

3D Printing

Sensor Integration

Python Programming

Embedded Systems

Education

Graduate Degree in Engineering

Tools

Fusion 360

Arduino

Raspberry Pi

Job description

Graduate Student in Engineering for Protein Therapeutics Device Development

Graduate Student in Engineering for Protein Therapeutics Device Development

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Graduate Student Opportunity in Engineering for Protein Therapeutics Device Development

Pardee Lab – University of Toronto

Start Date: Fall 2025

The Pardee Lab (www.pardeelab.org) at the University of Toronto is seeking graduate students with expertise in engineering to join our multidisciplinary team.The student would work alongside synthetic biologists in the lab to develop the next generation of devices for the distributed production of protein therapeutics and other molecular medicines at the point-of-need.

The recently funded project (https://cepi.net/transatlantic-scientists-transition-traditional-vaccine-development-rapid-response-platform-faster) marries engineering method-side innovation with cell-free synthetic biology and vaccine production, with a focus on the development of devices for the distributed production therapeutic proteins in benchtop, accurate, automated deployment-ready units.Through broader efforts in the lab, the student will also have an opportunity to work on projects dedicated to bringing biomanufacturing to the point-of-need, with implications for patients in Canada’s North, low- and middle-income countries, and personalized medicine.

Project Overview

This project focuses on designing, prototyping, and testing next-generation fluidic devices for automated, cell-free protein synthesis and purification.The successful candidate will be responsible for engineering a fluid-handling system that integrates precise temperature control, real-time optical monitoring, and automated process control. This involves developing and implementing fluidic and electronic systems and hardware-software interfaces to enable dynamic control of cell-free synthetic biology reactions.

Required Skills and Experience

The ideal applicant will have experience in most or all of the following areas:

• A strong engineering background in Mechanical, Electrical, Biomedical, Mechatronics, or a related discipline.
• Experience in device design and fabrication, including CAD software (e.g., Fusion 360), 3D printing, laser cutting, and CNC machining.
• Proficiency in mechatronics and hardware development, including sensor integration, electronics, and automation.
• Experience with systems integration, including hardware-software interfacing, graphical user interface development, real-time control, and automation.
• Strong programming skills for device control and data acquisition (e.g., Python, C++).
• Experience with microprocessor programming (e.g., Raspberry Pi, Arduino) and embedded systems.
• Experience in electronic circuit design, PCB layout, and circuit debugging.

Familiarity with molecular biology, biochemistry, and protein engineering principles is a bonus.

Opportunities for Growth

• Work in a collaborative, mission-driven environment at the forefront of biomanufacturing and synthetic biology.
• Gain hands-on experience with cutting-edge device prototyping, automation, and bioprocess integration.
• Collaborate with a diverse team of engineers, biologists, biochemists.
• Opportunity to learn protein expression and purification techniques, directed evolution, and computational protein design.
• Exposure to biomanufacturing process development for therapeutic proteins.

Application Instructions

To apply, please submit the following materials as a single PDF file via email to [e-mail]:

·Copy of transcripts

·Statement of Research Interests and Experience (specifically addressing your experience related to the responsibilities outlined above)

·Contact Information for Three References

Join us in advancing biomanufacturing innovation to make life-saving therapeutics more accessible worldwide!

All qualified candidates are encouraged to apply; however, Canadians and permanent residents will be given priority.

Seniority level

• Seniority level

  Internship

Employment type

• Employment type

  Full-time

• Industries

  Higher Education

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