Genomics Technician II — NGS & Sequencing Ops

Ontario Institute for Cancer Research; Toronto; On-site; CAD 57,000 - 63,000; Full time

Benefits offered by this job

Competitive benefits plan

Defined benefit pension (HOOPP)

Job summary

Ontario Institute for Cancer Research (OICR) is seeking a Research Technician II to apply advanced molecular biology skills to run the latest sequencing technologies, with a primary focus on Next-Generation Sequencing (NGS) platforms at the MaRS Centre in Toronto.

You will support validations, library prep, high-throughput sequencing operations, instrument QC, data handling in LIMS, and coordination with the Genomics Production team to ensure timely delivery of high-quality sequencing data.

Qualifications

• Bachelor’s degree in Molecular Biology or related field; equivalent experience considered.
• Experience with NGS library prep or sequencing instruments (Illumina or others).
• Experience with nucleic acid quantification and qPCR setup.

Responsibilities

• Perform automated and manual library construction and sequencing across NGS platforms.
• Prepare sample pools for sequencing QC and full-depth sequencing on Illumina and Ultima UG100 systems.
• Enter data into LIMS and track sequencing runs.
• Support senior staff to monitor QC tasks at steps in NGS workflows.
• Provide guidance and training for junior staff.
• Coordinate and prioritize sample processing with Genomics Production team.
• Document and communicate experimental results; contribute to SOP writing.
• Monitor and maintain lab equipment per accreditation guidance.
• Assist QA with quality improvement initiatives.

Skills

NGS library prep

QC tasks

Training junior staff

Data management in LIMS

Instrumentation troubleshooting

Documentation & SOPs

Team collaboration

Sample coordination

Attention to detail

Education

Bachelor’s degree in Molecular Biology or related field

Tools

Illumina sequencing platforms (MiSeq/NextSeq/NovaSeq X)

Ultima UG100 sequencer

LIMS software

Job description

Ontario Institute for Cancer Research (OICR) is seeking a Research Technician II to apply advanced molecular biology skills to run the latest sequencing technologies, with a primary focus on Next-Generation Sequencing (NGS) platforms at the MaRS Centre in Toronto.

You will support validations, library prep, high-throughput sequencing operations, instrument QC, data handling in LIMS, and coordination with the Genomics Production team to ensure timely delivery of high-quality sequencing data.