Formulation Assistant

COREALIS Pharma Inc.; Laval (administrative region); On-site; CAD 70,000 - 95,000; Full time

Job summary

COREALIS Pharma Inc. in Laval, QC is seeking a scientifically minded professional to support its oral solid dosage formulation development and pharmaceutical process development activities.

The role provides technical support to formulators during R&D, including literature reviews, equipment setup and cleaning, manufacturing, packaging, and physical testing of R&D batches. You will characterize APIs using XRPD, DSC, TGA, PSD and other tests; develop formulations and processes; select dosage

Qualifications

• BSc in Pharmaceutical Sciences or Master's in Drug Development (or equivalent experience).

Responsibilities

• Provide technical support to formulators during R&D activities (literature reviews, equipment setup and cleaning, manufacturing, packaging, and physical testing of R&D batches).
• Support technical and quality activities within the GMP pilot plant.
• Source laboratory consumables, equipment, and accessories, and provide purchasing recommendations.
• Perform other related duties as required.
• Characterize APIs using XRPD, DSC, TGA, DVS, PSD, density, flowability, compression testing, and other analytical techniques.
• Develop formulations and manufacturing processes.
• Select dosage forms (tablets, capsules, sachets), inactive ingredients (excipients), manufacturing processes, and packaging configurations.
• Analyze formulations (weight variation, hardness, friability, disintegration, moisture content, polymorphic form).
• Conduct stability studies.
• Prepare prototype formulations for pharmacokinetic studies in animal models.
• Prepare technical reports.

Education

B.Sc. in Pharmaceutical Sciences

Master's degree in Drug Development

Job description

Support oral solid dosage formulation development and pharmaceutical process development activities.

General Duties and Responsibilities:

Provide technical support to formulators during R&D activities (e.g., literature reviews, equipment setup and cleaning, manufacturing, packaging, and physical testing of R&D batches).

Support technical and quality activities within the GMP pilot plant.

Source laboratory consumables, equipment, and accessories, and provide purchasing recommendations.

Perform other related duties as required.

Specific Duties and Responsibilities:

Characterize active pharmaceutical ingredients (APIs) using XRPD, DSC, TGA, DVS, particle size distribution (PSD), density, flowability, compression testing, and other analytical techniques.

Develop formulations and manufacturing processes.

Select dosage forms (tablets, capsules, sachets), inactive ingredients (excipients), manufacturing processes, and packaging configurations.

Analyze formulations, including weight variation, hardness, friability, disintegration, API polymorphic form assessment, moisture content determination (LOD), and other physical tests.

Conduct stability studies.

Prepare prototype formulations for pharmacokinetic studies in animal models.

Prepare technical reports.

Qualifications and Skills:

B.Sc. in Pharmaceutical Sciences, Master's degree in Drug Development, or equivalent relevant work experience.

Reporting To:

Immediate Supervisor: To be determined.

Each role is integral to advancing OSD solutions and offers a unique chance to contribute to meaningful, industry-leading work.