Scientist - Product Development, Therapeutics

Title: Scientist - Product Development, Therapeutics

Location: Greater Vancouver, BC

Employment Type: Full-time, Permanent

Schedule: Onsite, Monday to Friday, 8-hour workdays

Reporting to: VP, R&D

Compensation: $85,000 - 110,000 Base Salary

Ready to drive life-changing therapies through monoclonal antibody and vaccine development? Looking for a new challenge in an innovative, collaborative biotech company making a real impact?

Company Overview

Our client, a leading biotechnology company based in Greater Vancouver, focuses on developing innovative monoclonal antibody and vaccine therapeutics to address global health challenges such as infectious and autoimmune diseases. With a collaborative and fast-paced culture, this company is ideal for professionals passionate about driving innovation in healthcare and creating transformative solutions.

If you’re a self-motivated team player who thrives in a dynamic environment and enjoys tackling complex challenges, this role is for you.

Position Summary

As a Scientist in Monoclonal Antibody and Vaccine Therapeutics Development, you will drive innovation by advancing the company’s pipeline of antibody-based therapies and next-generation vaccines. You will lead experimental research, optimize therapeutic and vaccine-related assays, and solve production challenges, ensuring the development of effective, high-quality monoclonal antibody products and vaccines.

Your expertise in antibody characterization, vaccine development, assay optimization, and problem-solving will be critical to advancing the pipeline of therapeutic products targeting infectious diseases, autoimmune conditions, or inflammatory disorders. This role requires a detail-oriented, independent thinker with a deep understanding of virology and immuno-based therapeutics.

Key Responsibilities

• Design, plan, and execute experiments and assays independently to support the development of monoclonal antibody products and vaccines.
• Enhance and refine assays for antibody and vaccine development (e.g., ELISA, cell-based functional assays, neutralization assays, potency assays, immunogenicity testing, and pharmacokinetic (PK) and pharmacodynamic (PD) studies) to ensure robust and reliable performance.
• Ensure compliance with ISO 13485 for quality management systems, ICH Q6B for specifications and testing, and ICH Q5A for viral safety.
• Contribute to standardizing laboratory procedures in line with ICH Q8 for pharmaceutical development and ICH Q9 for quality risk management.
• Collaborate with regulatory and quality teams to support risk management activities in accordance with ISO 14971 and GMP standards.
• Participate in validation studies to confirm monoclonal antibody and vaccine performance standards and ensure compliance with ICH Q2 for method validation.
• Characterize monoclonal antibodies and vaccines through binding, specificity, immunogenicity, and functional assays to support clinical and regulatory submissions.
• Analyze and summarize data critically, generating comprehensive reports and presentations for internal and external stakeholders.
• Provide technical guidance to troubleshoot and resolve issues, mentoring junior staff as needed.
• Develop a thorough understanding of virology’s role in autoimmune and infectious diseases and its integration into monoclonal antibody and vaccine therapies.
• Manage laboratory operations, including equipment maintenance and adherence to safety protocols.

Qualifications and Experience

• MSc or PhD in Virology, Immunology, Biotechnology, or a related life sciences field, with at least 5 years of industry experience in monoclonal antibody or vaccine development.
• Experience and familiarity with ISO 13485, ISO 14971, ICH Q5A, ICH Q6B, and ICH Q2 standards, as well as GMP/GLP guidelines for therapeutic and vaccine validation.
• Experience with hybridoma and recombinant antibody technologies is an asset.
• Knowledge of vaccine platforms such as mRNA, protein subunit, or viral vector-based systems is an asset.
• Exceptional communication, coordination, and problem-solving skills.
• Demonstrated ability to prioritize multiple tasks and excel in a fast-evolving environment.
• Legal authorization to work in Canada.

Contact Carla Campbell, TalentSphere - Life Sciences at ccampbell@talentpshere.ca for further information on this opportunity.