Clinical Trial Manager I — Site & Monitoring Lead

Syneos Health; Canada; On-site; CAD 80,000 - 110,000; Full time

Job summary

Syneos Health is seeking a Clinical Trial Manager I to lead site management and monitoring activities across assigned studies within Canada. The role emphasizes patient safety, data integrity, and regulatory compliance, with responsibility for timelines and budget adherence.

You will collaborate with study teams, CRO partners, and sponsors to ensure milestones are met and study quality is maintained. The successful candidate will manage CRA/central monitor teams, facilitate training, and

Qualifications

• Bachelor’s degree or RN with related experience in clinical operations
• Experience leading site management and monitoring activities
• Strong knowledge of GCP/ICH guidelines and regulatory requirements
• Ability to manage budgets and timelines across studies
• Excellent communication and cross-functional collaboration skills
• Proven ability to identify and mitigate risks in clinical trials

Responsibilities

• Oversees site management and monitoring deliverables with emphasis on patient safety and data integrity
• Manages site interactions from activation to closeout and handles investigator payments if needed
• Identifies risks and implements mitigations using CMP/SMP and monitoring plans
• Ensures timely delivery of metrics, dashboards and CTMS-related documentation
• Coordinates training for study teams on protocols, CRF completion, and SOPs
• Monitors resourcing for CRAs and central monitors and manages study team conduct
• Reviews and reports on study milestones, budgets and timelines
• Liaises with sponsors and other functional areas to ensure study goals are met

Skills

Site management

Clinical monitoring

Risk assessment

Data integrity

Regulatory compliance

Team leadership

Budget management

Data management

Communication

Education

Bachelor’s degree or RN

Tools

CTMS

EDC

Dashboards

ePROs

TMF

Job description

Syneos Health is seeking a Clinical Trial Manager I to lead site management and monitoring activities across assigned studies within Canada. The role emphasizes patient safety, data integrity, and regulatory compliance, with responsibility for timelines and budget adherence.

You will collaborate with study teams, CRO partners, and sponsors to ensure milestones are met and study quality is maintained. The successful candidate will manage CRA/central monitor teams, facilitate training, and