Clinical Trial Manager, Clinical Operations, Infectious Disease

Moderna Therapeutics; Toronto; On-site; CAD 110,000 - 170,000; Full time

Benefits offered by this job

Healthcare benefits

Well-being resources

Fertility, adoption, and surrogacy 지원

Generous paid time off and holidays

Job summary

Moderna Therapeutics in Toronto, a pioneering biotech, is seeking a Clinical Trial Manager for Infectious Disease Operations. You will oversee global clinical trial execution, partnering with sites, CROs, and internal teams to deliver high-quality studies on time and within regulatory standards.

With at least five years of trial coordination in a global setting and strong knowledge of FDA/ICH-GCP, you will drive timelines, data quality, and stakeholder collaboration while applying digital

Qualifications

• Bachelor's degree in science or related field; advanced degree preferred.
• At least 5 years of clinical trial coordination experience in a global environment.
• Strong knowledge of FDA regulations and ICH-GCP guidelines.

Responsibilities

• Provide day-to-day operational management of assigned clinical trial(s) across all study phases.
• Monitor study timelines, risks and deliverables with internal project teams.
• Lead feasibility activities to support study start-up.
• Coordinate with Clinical Operations Lead, other CTMs, sites, CROs.
• Develop site-facing materials, study manuals and supporting documentation.
• Ensure timely data entry and readiness for data review meetings.
• Maintain trial metrics and ensure compliance with regulatory requirements.
• Support UAT and testing for clinical trial systems and databases.

Skills

Clinical trial coordination

Project management

ICH-GCP

FDA regulations

Communication

Global clinical operations

Education

Bachelor's degree in a science-related discipline

Advanced degree preferred

Tools

Clinical trial systems

Job description

The Role:

Joining Moderna means advancing mRNA science to transform medicine. Work with exceptional global teams on a broad pipeline and build a career that makes a real difference for patients. Moderna is strengthening its presence in Toronto, a leading biotech hub in Canada. Our team drives commercial operations to bring our mRNA medicines to patients nationwide. We welcome global talent ready to help transform medicine and improve lives. As a Clinical Trial Manager within our Infectious Disease Clinical Operations team, you will play a critical role in delivering high-quality global clinical trials that advance Moderna's innovative mRNA pipeline. Working as an individual contributor, you will oversee the operational execution of assigned studies, ensuring clinical trial activities are delivered with excellence in quality, compliance and speed while partnering closely with internal teams, investigative sites, vendors and Contract Research Organizations (CROs). This role offers the opportunity to combine strong clinical operations expertise with outstanding project management and stakeholder collaboration skills. You'll help drive operational excellence across multiple studies while working with modern digital platforms and emerging Generative AI-enabled technologies that continue to enhance clinical trial execution, operational insights and data-driven decision making.

Here's What You'll Do:

• Provide day-to-day operational management of assigned clinical trial(s), ensuring deliverables are achieved across all phases of study execution.
• Monitor study timelines and communicate progress, risks and deliverables effectively with internal project teams.
• Lead and manage clinical trial feasibility activities to support successful study start-up.
• Partner closely with the Clinical Operations Lead and other Clinical Trial Managers to execute global clinical studies.
• Develop site-facing materials, including investigator training materials, study manuals and supporting documentation.
• Monitor clinical data to ensure timely data entry and readiness for data review meetings.
• Conduct periodic reviews of clinical data to support study quality and operational oversight.
• Review clinical monitoring reports to ensure timely completion, identify emerging issues and support appropriate follow-up actions.
• Ensure clinical trial samples are prepared and transferred to external vendors in alignment with study timelines and operational requirements.
• Maintain key clinical trial metrics to support study oversight and performance monitoring.
• Ensure assigned clinical trials are conducted in accordance with Moderna quality standards, ICH Good Clinical Practice (ICH-GCP) guidelines and applicable regulatory requirements across global regions.
• Support User Acceptance Testing (UAT) and testing activities for clinical trial systems and databases.
• Provide support for additional clinical trials in an unblinded Clinical Trial Manager capacity when required.
• Build and maintain strong collaborative relationships with key stakeholders across Moderna, external vendors, CROs and investigator sites.

Here's What You'll Bring to the Table:

• At least five years of clinical trial coordination experience within a clinical research and industry environment.
• Advanced degree preferred, or Bachelor's degree in a science‑related discipline.
• Experience supporting clinical trials within a global operating environment.
• Solid understanding of drug development and clinical trial execution.
• Strong project management skills with the ability to manage multiple priorities effectively.
• Good understanding of FDA regulations and ICH-GCP guidelines to ensure the compliant conduct of global clinical studies.
• Excellent written and verbal communication skills with the ability to collaborate effectively across multidisciplinary teams.
• Strong organisational skills, attention to detail and the ability to deliver high-quality work within a fast‑paced environment.
• As part of Moderna’s commitment to build a sustainable workforce, a minimum of 2 years of work authorization is required for this role.

The key Moderna Mindsets you’ll need to succeed in the role:

• “We act with urgency; Action today compounds the lives saved tomorrow.”
• “We remove viscosity to encourage collective action.”

Pay & Benefits

At Moderna, we believe that when you feel your best, you can do your best work. That’s why our global benefits and well‑being resources are designed to support you—at work, at home, and everywhere in between.

• Competitive healthcare, plus voluntary benefit programs to support your unique needs
• A holistic approach to well‑being with access to fitness, mindfulness, and mental health support
• Family building benefits, including fertility, adoption, and surrogacy support
• Generous paid time off, including vacation, bank holidays, volunteer days, sabbatical, global recharge days, and a discretionary year‑end shutdown
• Savings and investments to help you plan for the future
• Location‑specific perks and extras

The benefits offered may vary depending on the nature of your employment with Moderna and the country where you work.

The salary range for this role is $0.00 - $0.00. This range reflects the minimum and maximum base pay we expect to pay for this position based on our current compensation structure. The actual base pay offered to each employee is determined with due diligence, taking into account factors such as relevant experience, skills, qualifications, education, performance, and business requirements. We regularly review pay ranges and individual compensation to ensure competitiveness with the external market and to maintain internal equity in alignment with our company’s compensation and pay‑transparency principles.

The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or an equity award, subject to applicable plan eligibility criteria and individual performance. Please note that this information is provided for transparency and compliance purposes. It does not constitute a contractual commitment or guarantee of a specific rate of pay.

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world‑class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities. We are proud to have been recognized as a ScienceMagazine TopBiopharma Employer, a FastCompany Best Workplace for Innovators, and a Great Place to Work in the U.S. As we build our company, we have always believed an in‑person culture is critical to our success. Moderna champions the significant benefits of in‑office collaboration by embracing a 70/30 work model. This 70% in‑office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship.

Moderna is a smoke‑free, alcohol‑free, and drug‑free work environment. Moderna is a place where everyone can grow. Moderna is committed to equal opportunity in employment and non‑discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. We consider qualified applicants regardless of criminal histories, consistent with legal requirements. We’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best. Moderna is committed to offering reasonable accommodation or adjustments to qualified job applicants with disabilities. Any applicant requiring an accommodation or adjustment in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations and Adjustments team at [e-mail].

Third Party Staffing Agencies

Moderna does not accept unsolicited resumes from any source other than directly from candidates. For the protection of all parties involved in the recruiting process, resumes will only be accepted from recruiters/agencies if a signed agreement is in place at the inception of the recruiting effort and authorized for a specified position. Unsolicited resumes sent to Moderna from recruiters/agencies do not constitute any type of relationship between the recruiter/agency and Moderna and do not obligate Moderna to pay fees if we hire from those resumes.

Reasonable Accommodation Notice

Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Applicants with disabilities may be entitled to reasonable accommodation under the terms of the Americans with Disabilities Act and certain state or local laws. Please inform the company's personnel representative by calling 617-460-9346 or emailing [e-mail] if you need assistance completing any forms or to otherwise participate in the application process. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment.

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