24.11.07 Postdoctoral Fellow, Cherkasov Lab - Vancouver Prostate Centre

Computational Chemistry List, Ltd. (CCL); Vancouver; On-site; CAD 60,000 - 100,000; Full time

Job summary

An exceptional opportunity awaits a talented Postdoctoral Fellow in a leading research lab focused on innovative cancer therapeutics. Join a dynamic team at a National Centre of Excellence, where you will engage in groundbreaking drug discovery programs utilizing cutting-edge deep-learning techniques. This role offers the chance to contribute to state-of-the-art research in computational chemistry and drug design, making a significant impact in the field. Ideal candidates will possess strong programming skills in Python and Bash, along with a solid foundation in various chemistry disciplines. If you're passionate about advancing cancer research through technology, this position is your gateway to a rewarding career.

Qualifications

• Demonstrated research background in computer-aided drug design.
• Experience with deep-learning docking strategies and virtual screening.

Responsibilities

• Work on drug discovery programs using deep-learning strategies.
• Support structure-based and ligand-based virtual screening.

Skills

Problem-solving skills

Deep-learning programming with GPUs

Statistical data analysis

Database management

Python programming

Bash programming

Computational chemistry knowledge

Biological chemistry knowledge

Organic chemistry knowledge

Medicinal chemistry knowledge

Pharmacokinetics knowledge

Drug design experience

Cheminformatics tools familiarity

Education

PhD in relevant field

Tools

MOE

Schrodinger

OpenEye suite of programs

Job description

Postdoctoral Fellow, Cherkasov Lab - Vancouver Prostate Centre

The Vancouver Prostate Centre (VPC) has an exceptional opportunity available for a Postdoctoral Research Fellow in the Cherkasov Lab to join our research team. The VPC has a large number of multi-disciplinary research programs in basic, clinical, and translational cancer research. It is a National Centre of Excellence and a designated Centre of Excellence for Commercialization and Research, affiliated with the University of British Columbia and the Vancouver Coastal Health Authority. Further details on VPC and its research programs are available at www.prostatecentre.com.

Cherkasov Lab
Dr. Artem Cherkasov is a Professor in the Department of Urologic Sciences, Faculty of Medicine at the University of British Columbia, and Senior Scientist at the Vancouver Prostate Centre. His research interests include computer-aided drug discovery (CADD), structure-activity modeling, drug reprofiling, new cancer therapeutics discovery, and development of novel CADD tools and applications. More information on Dr. Cherkasov and his team can be found at www.prostatecentre.com/about-us/people/dr-art-cherkasov.

Qualifications and Requirements
Professor Artem Cherkasov is looking for a talented Postdoctoral Fellow with a demonstrated research background and experience in computer-aided drug design. The Postdoctoral Fellow will work on exciting drug discovery programs providing cutting-edge deep-learning docking strategies to support structure-based and ligand-based virtual screening and lead optimization. Required qualifications include:

1. Strong problem-solving and efficient communication skills.
2. Strong deep-learning programming experience with GPUs.
3. Statistical data analysis and database management skills.
4. Strong Python and Bash programming skills.
5. Strong portfolio of open-source software available on GitHub.
6. Solid background in computational chemistry, biological chemistry, organic chemistry, medicinal chemistry, and pharmacokinetics.
7. Hands-on experience in structure-based and ligand-based drug design and compound library design.
8. Familiarity with state-of-the-art modeling and cheminformatics tools such as MOE, Schrodinger, and OpenEye suite of programs.

Application Procedures
To apply for this position, please email [e-mail] with the subject line 'Postdoctoral Research Fellow, Cherkasov Lab' and the following items attached:

1. Current CV
2. Cover letter

NOTES: This position will remain open until a suitable candidate is found. No telephone calls or drop-in inquiries accepted. Only those under consideration will be contacted. All qualified candidates are encouraged to apply; however, Canadians and permanent residents will be given priority.

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