Senior Clinical Data Engineer (LATAM)

Precision Medicine Group; Brasil; Remote; BRL 180,000 - 360,000; Full time

Job summary

Precision Medicine Group is expanding its clinical data engineering capabilities across multiple countries including Brazil. We’re seeking a Senior Clinical Data Engineer to lead the development of clinical data systems, ensure regulatory alignment, and drive data standardization for global trials.

You will mentor engineers and partner with Biostatistics, Clinical Operations, and Regulatory Affairs. The role requires advanced SAS programming, strong data governance, and experience building

Qualifications

• Bachelor’s degree in life sciences, data management, or related field with equivalent experience
• 6+ years in clinical data management, monitoring, or related roles
• Strong programming and automation skills; DB design; dashboard development; CDISC governance
• Professional working proficiency in English; excellent communication and collaboration skills
• Ability to mentor junior engineers and work with cross-functional teams
• Regulatory alignment experience with GCP and FDA 21 CFR Part 11 preferred

Responsibilities

• Lead development and optimization of clinical data systems for regulatory compliance and analytics
• Drive data standardization and enterprise-wide data mapping strategies
• Design and implement robust validation frameworks to ensure data quality
• Architect modular SAS-based codebases; mentor juniors in automation and performance
• Oversee documentation and audit trails to support inspections
• Collaborate with Biostatistics, Clinical Operations, and Regulatory Affairs to translate requirements into scalable solutions
• Lead design of secure, high-performance databases and ETL pipelines across trials

Skills

Data engineering

SAS programming

Python

SQL

Data governance

Education

Bachelor’s Degree in life sciences / data management

Tools

SAS

Python

SQL

R

Job description

We’re expanding our data engineering capabilities acrossMexico, Brazil, Argentina, Colombia, Chile, and Peru, and we’re hiring a Senior Clinical Data Engineer to help build the foundation of this new regional function. In this role, you’ll lead the development and optimization of clinical data systems, drive data standardization, build validation frameworks, and design high‑performance databases and pipelines across global trials.The Senior Clinical Data Engineer leads the strategic development and optimization of clinical data systems to support regulatory compliance, advanced analytics, and operational excellence across global trials.This role drives enterprise-level data standardization initiatives, and architects scalable validation frameworks to proactively address systemic data issues. With deep expertise in SAS Programming in a Life Sciences setting, you'll be responsible for building and maintaining modular codebases, sets coding standards, and mentoring junior engineers. The role also oversees regulatory alignment with GCP and FDA 21 CFR Part 11, establishing robust documentation and audit trail protocols.Through dynamic dashboards and analytics tools, you'll deliver actionable insights into trial performance and data quality. As a strategic liaison across Biostatistics, Clinical Operations, and Regulatory Affairs, you'll help translate clinical requirements into scalable technical solutions and leads the design of secure, high-performance databases and ETL pipelines integrating data from diverse clinical systems.

Essential functions of the job include but are not limited to:

• Data Standardization & Mapping: Spearhead the development of enterprise-level data mapping strategies that transform raw clinical data into standardized formats for high-impact analytics. Lead the adoption and governance of data standards across programs to ensure regulatory alignment and consistency.
• Data Quality Assurance: Design and implement robust, scalable validation frameworks that proactively detect and resolve systemic data issues. Serve as a strategic partner to Clinical Data Managers and cross-functional teams, driving continuous improvement in data integrity across global trials
• Programming & Scripting: Architect and maintain advanced, modular codebases using SAS to support complex data engineering workflows. Python, R, and SQL experience is highly preferred as we continue to leverage Ai tools across the industry. Establishing coding standards and mentoring junior engineers in automation, reproducibility, and performance optimization. Example use cases includes edit checks, reconciliations, exception listings, programmed protocol deviations, resource projections based on site data entry volume
• Regulatory Compliance & Documentation: Lead compliance initiatives to ensure all data systems and workflows meet GCP, FDA 21 CFR Part 11, and evolving global regulatory requirements. Define documentation protocols and oversee audit trail governance to support inspection readiness and transparency.
• Reporting & Visualization: Develop and operationalize dynamic dashboards and analytics tools that provide real-time insights into data quality, trial progress, and operational KPIs. Translate complex datasets into actionable intelligence for clinical and regulatory stakeholders.
• Collaboration & Cross-Functional Support: Act as a strategic liaison between Clinical Data Engineering and Biostatistics, Clinical Operations, and Regulatory Affairs. Translate clinical and scientific requirements into scalable technical solutions that support study execution and data delivery.
• Database Design & Optimization: Lead the design and optimization of secure, high-performance relational databases and data lakes. Ensure infrastructure scalability, query efficiency, and data governance for large-scale clinical datasets.

QualificationsMinimum Required:

• Bachelor’s Degree in a relevant field (life sciences, statistics, data management, clinical operations) or relevant/equivalent combination of education, training, and experience
• Minimum 6 years experience in clinical monitoring, clinical trial management or equivalent
• Advanced programming and automation skills; database design; dashboard development; CDISC governance
• Professional working proficiency in English
• Other Required
• Highly effective oral and written communication skills with the ability to communicate effectively with project team members
• Excellent organizational and time management skills
• Ability to work in a team or independently as required
• Demonstrated ability to learn how to extract pertinent information from protocols, electronic study data systems and clinical systems
• Proficiency in statistical analysis and data monitoring tools
• Detail-oriented with strong analytical and problem-solving skills
• Demonstrated experience with integrated risk planning & management
• Ability to mentor junior team members
• PreferredCRO experience as a Clinical Data Engineer or ProgrammerAutomation and Ai Agent Deployment in Regulated EnvironmentsSkillsStrong analytical and problem-solving skills with attention to data quality and integrityAbility to work with large, complex datasets from multiple sourcesEffective communication skills to collaborate with cross-functional teamsKnowledge of data governance, privacy, and security best practices in clinical research.

Competencies

• Collaboration: Works effectively with clinical, statistical, and technical teams to align data strategies with study goals.
• Accountability: Takes ownership of data engineering deliverables and ensures timely, high-quality outputs.
• Adaptability: Thrives in a fast-paced, evolving environment with shifting priorities and timelines.
• Compliance-Oriented: Maintains a strong focus on regulatory compliance and data traceability.

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Precision Medicine Group is an Equal Opportunity Employer. Employment decisions are made without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status or other characteristics protected by law.

If you are an individual with a disability and require a reasonable accommodation to complete any part of the application process or are limited in the ability or unable to access or use this online application process and need an alternative method for applying, you may contact Precision Medicine Group at [e-mail].

Candidates must be legally authorized to work in the country of employment without employer sponsorship.