Sr Scientist Biostatistics
Johnson & Johnson Co.
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Descrizione del lavoro
Johnson & Johnson is seeking a Senior Scientist in AI and Biostatistics to develop AI-enabled statistical solutions for pharmaceutical research and manufacturing. You will combine statistical rigour with AI approaches, collaborating across domain experts and technology teams to ensure scalable, validated outcomes.
Role spans Beerse, Leiden, Prague, Maidenhead, Spring House, Raritan and Titusville locations, with emphasis on trustworthiness, traceability and governance in a regulated setting.
Competenze
- Advanced degree in quantitative field or equivalent experience.
- Strong statistical modelling, study design and validation knowledge.
- Ability to communicate trade-offs clearly in English.
Mansioni
- Develop AI-enabled statistical solutions for pharma research and manufacturing.
- Ensure statistical integrity, uncertainty handling and generalisability.
- Design end-to-end architectures for production scientific AI applications.
Conoscenze
Formazione
Strumenti
Descrizione del lavoro
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com.
As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.
Job Function:
Data Analytics & Computational Sciences
Job Sub Function:
Biostatistics
Job Category:
Scientific/Technology
All Job Posting Locations:
Beerse, Antwerp, Belgium, Leiden, Netherlands, Maidenhead, Berkshire, United Kingdom, Prague, Czechia, Raritan, New Jersey, United States of America, Spring House, Pennsylvania, United States of America
Job Description:
Senior Scientist in AI and Biostatistics
The Discovery and Manufacturing Statistics organization within Johnson & Johnson is seeking a biostatistician with strong training and demonstrated applied experience in AI. The successful candidate will combine rigorous statistical thinking with expertise in modern AI technologies in order to develop trustworthy, validated and reusable AI-enabled statistical solutions for pharmaceutical research and manufacturing.
The individual will work at the intersection of biostatistics, artificial intelligence and scientific software development and will ensure that AI solutions are not only technically scalable, but also statistically sound, scientifically interpretable and appropriate for decision-making in a regulated and validation-sensitive environment.
Working with domain experts and technology teams, the successful candidate will combine hands-on development with large language models (LLMs), retrieval-augmented generation (RAG) and agentic workflows. The role supports the integration of scientific intelligence into evolving digital and laboratory environments, with reproducibility, traceability and expert oversight.
Locations: Beerse (Belgium), Leiden (the Netherlands), Prague (Czechia), Maidenhead (UK), Spring House (PA), Raritan (NJ), Titusville (PA)
- Make statistical, mechanistic and predictive models accessible to AI workflows through documented interfaces and shared model services. Build Python services and connect approved R and Python tools through APIs and Model Context Protocol (MCP).
- Be accountable for the statistical integrity of AI-enabled solutions, ensuring appropriate treatment of variability, uncertainty, confounding factors and generalisability of findings.
- Design, develop and deploy AI-enabled scientific applications that integrate statistical methods, machine learning, generative AI and domain knowledge into scalable and reusable solutions.
- Develop agentic workflows that retrieve evidence, invoke scientific models and support interpretation and proposed next experiments. Incorporate controlled tool execution, error handling and human review.
- Prepare, curate and contextualise scientific data, experimental results and documents for AI applications. Ensure appropriate treatment of data quality, metadata, provenance and uncertainty, and contribute to knowledge-graph and semantic-integration initiatives where relevant.
- Collaborate with modelling and laboratory automation teams on iterative workflows that connect experimental results, model updates and experimental design while maintaining scientific rigour, traceability and governance.
- Work with platform and security teams to deploy and operate applications, including access controls, configuration, logging, monitoring and validation.
- Design end-to-end architectures for production scientific AI applications, covering user interfaces, services, APIs, data, models and deployment. Define integration patterns that fit shared enterprise platforms.
- Test applications and evaluate retrieval, tool use and generated outputs. Work with domain experts to assess scientific validity, uncertainty and limitations, and investigate failures.
- Contribute to the development of reusable statistical and AI capabilities across DMS, including documentation, software components, analytical frameworks, validation approaches, best practices and technical standards.
- Serve as a scientific and technical thought leader by educating and mentoring statisticians and scientists in the effective application of AI, machine learning and modern computational methods.
Required qualifications
- PhD in Statistics, Biostatistics, Machine Learning, Data Science, Computer Science, Artificial Intelligence or a related quantitative discipline, or a Master’s degree with commensurate relevant experience.
- Candidates whose primary degree is in Computer Science, AI or Software Engineering must demonstrate advanced knowledge and practical application of statistical modelling, study design, uncertainty quantification and model validation.
- Ability to communicate technical trade-offs clearly in English, and collaborate with colleagues from different scientific and technical backgrounds.
- Strong foundations in statistical inference and predictive modelling.
- Understanding of study and experimental design.
- Experience assessing uncertainty, bias, overfitting and generalizability.
- Experience with model validation, calibration and performance evaluation.
- Proficiency in R and/or Python for statistical analysis.
- Ability to explain complex statistical and AI concepts to scientific audiences.
- Hands-on experience developing AI or machine-learning solutions.
- Experience with generative AI, large language models, retrieval-augmented generation or agentic workflows.
- Demonstrated experience designing end-to-end architectures for production applications, including service boundaries, data flows, API contracts, security, scalability, reliability and observability, with the ability to explain architectural trade-offs.
- Strong Python skills and familiarity with building maintainable APIs and services. Working knowledge of SQL, data pipelines and data-quality controls.
- Experience building modular, tested and reproducible analytical software (Git).
- Understanding of AI evaluation, monitoring and responsible-use considerations.
- Ability to connect AI components beyond the proof-of-concept stage to validated statistical or scientific functions.
- Experience moving AI or statistical solutions from prototype to a supported production application.
Experience in one or more of the following areas would be valuable:
- Pharmaceutical, biotechnology, healthcare or other regulated or validation-sensitive environments.
- Experience with manufacturing, discovery, omics or other complex scientific data.
- Experience with Bayesian modelling, design of experiments, mixed models, causal inference or high-dimensional data.
- Scientific modelling, active learning or optimisation, particularly in iterative experimental workflows.
- RAG evaluation, hybrid retrieval, knowledge graphs and contextualization of scientific data.
- MCP, agent orchestration, shared model services and workflows combining automated checks with expert review.
- R package development, Shiny, Quarto, interoperable R/Python workflows, FastAPI or modern web interfaces; familiarity with Posit Workbench or Posit Connect.
- Hosted or self-hosted model APIs, LLM serving frameworks such as vLLM, and enterprise deployment environments.
- AI observability, access enforcement, prompt-injection defenses and responsible handling of sensitive data.
Required Skills:
- Advanced Analytics
- Biostatistics
- Clinical Trials
- Collaboration
- Consulting
- Critical Thinking
- Data Privacy Standards
- Data Quality
- Data Savvy
- Digital Fluency
- Good Clinical Practice (GCP)
- Quality Assurance (QA)
- Report Writing
- Standard Operating Procedure (SOP)
- Statistical Analysis Systems (SAS) Programming
- Statistics
- Systems Development
- Technologically Savvy
Preferred Skills:
- Advanced Analytics
- Biostatistics
- Clinical Trials
- Collaboration
- Consulting
- Critical Thinking
- Data Privacy Standards
- Data Quality
- Data Savvy
- Digital Fluency
- Good Clinical Practice (GCP)
- Quality Assurance (QA)
- Report Writing
- Standard Operating Procedure (SOP)
- Statistical Analysis Systems (SAS) Programming
- Statistics
- Systems Development
- Technologically Savvy
Benefits:
In addition to base pay, we offer the following benefits*: an annual bonus with set target (% of pay) depending on pay grade / location, where the actual amount is based on the employees’ and companies’ performance of the previous calendar year, or sales commissions. Moreover, we offer vacation days, parental leave for a minimum of 12 weeks, bereavement leave, caregiver leave, volunteer leave, well-being reimbursement, programs for financial, physical and mental health. We also offer service anniversary and recognition awards, and subject to the terms of their respective plans, employees - and in some location’s eligible dependents - can participate in several insurance plans. For more information, visit Employee benefits | Supporting well-being & career growth | Johnson & Johnson Careers.
*This is for informative purposes only. Amounts and actual benefits may vary by location and are subject to change.
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