Principal Scientist, Preclinical Strategy & Discovery

Enodia Therapeutics; Luik; On-site; EUR 120,000 - 180,000; Full time

Benefits offered by this job

Stimulating position within biotech

Dynamic, respectful environment

Challenging scientific and business成长

Attractive salary package

Job summary

Enodia Therapeutics is seeking an experienced Principal Scientist to provide expert scientific leadership across discovery and preclinical programs, shape approaches to target biology, drug mechanisms and Sec61 inhibition.

The successful candidate will integrate multidisciplinary evidence, influence methodologies, guide experimental strategy and collaborate with academic partners, KOLs and CROs to advance the pipeline.

Qualifications

• PhD and/or postdoctoral experience in Immunology, Oncology, Tumor Immunology or another field relevant to Enodia's programs.
• Extensive relevant research experience in biotech/pharma or a comparable academic environment specifically in building datasets in support of IND/CTA submissions.
• Recognized depth and/or breadth of scientific expertise relevant to target biology, drug discovery and preclinical research including preclinical models.
• Demonstrated ability to integrate multiple experimental approaches and data types to address complex program-level scientific questions.
• Strong track record of scientific productivity and meaningful contribution to drug discovery or complex research programs.
• Demonstrated ability to influence scientific strategy and decision-making across projects through expertise, critical thinking and evidence-based recommendations.
• Strong scientific leadership, mentoring, communication and collaboration skills, without requiring formal people-management responsibility.
• Excellent command of English, strong autonomy, rigor, effective time management and adaptability.

Responsibilities

• Lead the scientific strategy and cross-functional efforts to build a robust preclinical data package that successfully transitions candidates into clinical development.
• Provide recognized cross-project scientific expertise and influence scientific approaches, methodologies and complex problem-solving.
• Shape experimental strategy for complex target biology and drug discovery questions and guide the selection and integration of relevant models, assays and technologies.
• Integrate complex and multidisciplinary scientific data to generate hypotheses, challenge assumptions and guide program-level recommendations and next steps.
• Influence scientific direction across projects by connecting findings to target validation, mechanism of action, therapeutic potential and key project decision points.
• Provide scientific guidance, mentoring and constructive challenge to project teams and less experienced colleagues.
• Communicate complex scientific findings, recommendations, uncertainties and risks clearly to project, senior and relevant external audiences.
• Maintain broad scientific awareness and collaborate with external academic partners, KOLs and CROs where relevant.

Skills

Immunology

Oncology

Drug discovery

Scientific leadership

Data integration

Education

PhD in Immunology/Oncology/related

Job description

Enodia Therapeutics is seeking an experienced Principal Scientist to provide expert scientific leadership across discovery and preclinical programs, shape approaches to target biology, drug mechanisms and Sec61 inhibition.

The successful candidate will integrate multidisciplinary evidence, influence methodologies, guide experimental strategy and collaborate with academic partners, KOLs and CROs to advance the pipeline.