Senior Scientific Officer/Trials Analyst

Newcastle University; Newcastle; Vor Ort; GBP 37.000 - 44.000; Vollzeit

Benefits dieser Stelle

Generous holiday package

Health and wellbeing initiatives

Pension schemes

Zusammenfassung

Newcastle University is seeking a Senior Scientific Officer/Trials Analyst to manage analytic assays and coordinate cancer pharmacology research projects. The role involves leading projects, validating novel assays, and applying high-level assay development in a clinical pharmacology context.

You will work under the Institute Technical Manager and Professor Gareth Veal, contributing to high standards of professional service, research collaboration, and dissemination of findings within national

Qualifikationen

• Detailed knowledge of clinical pharmacology assay development and regulatory standards.
• Experience in clinical research and independent project management.
• Experience working to GCLP standards.

Aufgaben

• Develop and validate analytical assays using specialist equipment with high skill.
• Provide expert advice on experimental design, assay validation, and logistics to staff and external collaborators.
• Lead multiple projects to meet deadlines for pharma, sponsors, and regulatory agencies.
• Manage resources across projects, prioritise equipment use, and coordinate with external partners.
• Develop new analytical methods and upgrade facilities, including equipment procurement.

Kenntnisse

GCLP knowledge

Analytical skills

Chromatographic assays

Project coordination

Leadership

Time management

Communication skills

Training and mentorship

Budgeting and costings

Team collaboration

Ausbildung

Degree in a relevant subject

Higher degree desirable

Tools

LC/MS

HPLC

Jobbeschreibung

Salary: £37,369 - £44,352 per annum

Newcastle University is a great place to work, with excellent benefits. We have a generous holiday package; plus the opportunity to buy more, great pension schemes and a number of health and wellbeing initiatives to support you.

Closing Date: 13 November 2026

The role

The Senior Scientific Officer/Trials Analyst will be responsible for the management of a suite of analytical equipment and coordination of research projects in the Newcastle Cancer Centre Pharmacology Group of Professor Gareth Veal, a leading international centre in the development and validation of clinical pharmacology assays in the field of oncology. The role involves the coordination and management of multiple projects relating to the analysis and quantification of anticancer drug levels in clinical samples obtained as part of national clinical pharmacology trials. Additional preclinical assay development work may also be involved, with all work carried out according to GCLP regulations. You will take responsibility for leading individual projects, involving the validation of novel assays and analysis of clinical samples, and the implementation of new programs of research utilising your high level of expertise in assay development. This expansive role will incorporate the costing of collaboration with a wide variety of people including university research staff/students, analytical technicians from external companies, clinicians/research nursing staff in national treatment centres and representatives from charities and funding bodies.

Reporting to the Institute Technical Manager team and Professor Veal, you will be a visible role model, demonstrating the highest standards of leadership and behaviour and contributing to the development of an outstanding professional service.

The Newcastle Cancer Centre Pharmacology Group is a dedicated team of experienced researchers. We have a proven track record in running clinical pharmacology studies in an oncology setting, working in close collaboration with Cancer Research UK, academia and pharma and biotech companies https://www.ncl.ac.uk/cancer/our-research/late-phase-trials/pharmacology/.

Further information can be obtained by contacting Professor Gareth Veal [e-mail].

Find out more about the Faculty of Medical Sciences here: https://www.ncl.ac.uk/medical-sciences/

The post is full time, fixed term until 31/02/2028.

Key Accountabilities

• Development and validation of analytical assays using highly specialist equipment, requiring the application of a high level of skill and expertise, obtained through many years of experience
• Provision of expert advice and management in all aspects of clinical pharmacology assay development (e.g. advising on experimental design and feasibility, assay validation, logistics, etc) to a wide range of staff, students and commercial users
• Provision of expert advice and management in all aspects of clinical pharmacology assay development (e.g. advising on experimental design and feasibility, assay validation, logistics, etc) to a wide range of staff, students and commercial users
• Liaison with PIs and research staff within the institute and wider university to facilitate the running of multiple research projects to meet defined deadlines. This role involves both scientific input (assessment of requirements and analysis of data) in addition to forward planning skills required to prioritise equipment usage by various users and multiple projects to meet deadlines for pharmaceutical companies, sponsors and regulatory agencies
• Development of new/improved analytical methods and facilities, by keeping up to date with developments in the field to enable an ongoing understanding of cutting-edge technologies. Developing business cases for the upgrading of the pharmacology group analytical facilities, including the procurement of new equipment
• Work with PIs to devise and review research proposals, grant applications and costings to ensure feasibility, accuracy and cost efficiency within the term of the project plan, bearing in mind the requirement for equipment usage across multiple research projects and groups
• Devise and implement strategies and decisions in order to most efficiently allocate resources to meet aims and objectives across multiple projects involving charities, pharma and regulatory agencies in a fast-moving environment
• Initiate and develop enterprise opportunities and foster and maintain established links with national and internationally recognised companies and organisations
• Maintain critical laboratory equipment including troubleshooting and making essential repairs. Identify serious faults and liaise with service contract technicians to coordinate repairs
• Provide training in analytical assays to staff at all levels
• Develop and validate assays (LC/MS, HPLC) for the quantification of cancer drugs
• Analyse drug levels in clinical samples from patients recruited to clinical trials, working according to GCLP practices at all times
• Make a significant contribution to research through the compilation of clinical pharmacology data for internal and external reports and publications
• Provide input into the publication of scientific data generated from both preclinical work and clinical trials, with authorship expected on multiple projects
• Be aware of and take responsibility for working in accordance with applicable regulations and guidance
• Provide regular updates regarding status of ongoing clinical trial work and projects
• Supervise undergraduate and postgraduate students
• Take responsibility for identifying own learning needs
• Contribute to the training and mentorship of new research and clinical trial staff
• In line with agreed goals and objectives, attend conferences, seminars and/or courses to ensure knowledge is up to date
• Undertake other reasonable duties or responsibilities as requested

The Person (Essential)

Knowledge, Skills and Experience

• Detailed subject knowledge in the area of research
• Experience of working in clinical research with experience of conducting independent research projects
• Knowledge and experience of working to standards of GCLP
• Excellent analytical skills and understanding of chromatographic assays and systems
• Experience of research with clear transferable skills and some experience or awareness of the research environment
• Excellent organisational skills
• Excellent interpersonal skills
• Experience in pharmacological assay development
• Experience in the maintenance of HPLC and LC/MS systems and experience in the use of LC/MS and HPLC for drug quantification
• Experience of preparing grant applications for submission to funding bodies
• Well developed understanding of health and safety regulations and procedures within an analytical laboratory

Attributes and Behaviour

• Commitment to continuing professional development
• Understanding of ethical issues surrounding clinical research involving patients
• Desire and ability to work as part of a team
• Strong commitment to the study of clinical pharmacology
• Ability to work independently on individual research projects
• Ability to communicate clearly and concisely in writing and verbally

Qualifications

• Degree or equivalent level qualification in a relevant subject
• A higher degree is desirable

Newcastle University is a global University where everyone is treated with dignity and respect. As a University of Sanctuary, we aim to provide a welcoming place of safety for all, offering opportunities to people fleeing violence and persecution.

We are committed to being a fully inclusive university which actively recruits, supports and retains colleagues from all sectors of society. We value diversity as well as celebrate, support and thrive on the contributions of all of our employees and the communities they represent. We are proud to be an equal opportunities employer and encourage applications from individuals who can complement our existing teams, we believe that success is built on having teams whose backgrounds and experiences reflect the diversity of our university and student population.

At Newcastle University we hold a Gold Athena Swan award in recognition of our good employment practices for the advancement of gender equality. We also hold a Race Equality Charter Bronze award in recognition of our work towards tackling race inequality in higher education REC. We are a Disability Confident employer and will offer an interview to disabled applicants who meet the essential criteria for the role as part of the offer and interview scheme.

In addition, we are a member of the Euraxess initiative supporting researchers in Europe.

Requisition ID: 29891