Principal Clinical Scientist

Alignerr; Melbourne; Remote; AUD 83,000 - 165,000; Part time

Benefits offered by this job

Fully remote

Freelance autonomy

Flexible schedule

Job summary

Alignerr is seeking a Principal Clinical Scientist (AI Training) for a fully remote, hourly contract. You will shape how AI reasons about biomedical evidence and ensure regulator-ready datasets meet submission standards.

The role targets senior clinical professionals who can work independently on flexible hours (10–40 hours/week) and collaborate with global AI research teams.

Qualifications

• Senior-level experience designing clinical trial protocols for regulatory submission.
• Deep expertise interpreting clinical data for major regulatory agencies (FDA/EMA).
• Strong grounding in clinical research methodology, biostatistics, or translational science.
• Meticulous, detail-oriented, and comfortable working independently in an asynchronous environment.
• Clear and precise written communicator with structured, actionable explanations.

Responsibilities

• Design and review clinical trial protocols used to generate regulator-ready datasets for AI training.
• Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance.
• Evaluate AI-generated clinical analyses for scientific soundness and alignment with FDA/EMA expectations.
• Provide expert, structured feedback that improves how AI models reason about trial data, endpoints, and outcomes.
• Help define the gold standard for how clinical evidence is represented and understood within AI systems.

Skills

Clinical trial design

Regulatory submissions

Data interpretation

Biostatistics

Independent work

Technical writing

Tools

AI tools

Job description

Principal Clinical Scientist (AI Training)

About The Role

What if your years of clinical trial expertise could directly shape how AI reasons about biomedical evidence — influencing the systems that will power the next generation of clinical research?

We're looking for a Principal Clinical Scientist to bring senior-level rigor to AI-driven research workflows. You'll work with cutting-edge AI systems developed alongside the world's leading research labs, ensuring that clinical data used to train and evaluate these models meets the exacting standards expected in real-world regulatory submissions.

This is a fully remote, flexible contract role — built for senior clinical professionals who want meaningful, high-impact work on their own schedule.

• Organization: Alignerr


• Type: Hourly Contract


• Location: Remote


• Commitment: 10–40 hours/week

What You'll Do

• Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training


• Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance


• Evaluate AI-generated clinical analyses for scientific soundness and alignment with FDA, EMA, or equivalent agency expectations


• Provide expert, structured feedback that directly improves how AI models reason about clinical trial data, endpoints, and outcomes


• Help define the gold standard for how clinical evidence is represented and understood within advanced AI systems

Who You Are

• Senior-level experience designing clinical trial protocols intended for regulatory submission


• Deep expertise interpreting clinical data for major regulatory agencies (FDA, EMA, or equivalent)


• Strong grounding in clinical research methodology, biostatistics, or translational science


• Meticulous, detail-oriented, and comfortable working independently in an asynchronous environment


• Clear and precise written communicator — you can explain complex clinical reasoning in structured, actionable terms

Nice to Have

• Prior experience with data annotation, data quality review, or evaluation systems


• Background in pharmacovigilance, medical writing, or clinical operations


• Familiarity with AI tools or data evaluation workflows

Why Join Us

• Work directly on frontier AI systems making a real impact on clinical and biomedical research


• Fully remote and flexible — work when and where it suits you


• Freelance autonomy with the structure of meaningful, expert-level work


• Influence how AI understands and evaluates real-world clinical evidence at a foundational level


• Collaborate with a global network of domain experts and leading AI research teams


• Potential for ongoing work and contract extension as new projects launch