Principal Clinical Scientist

Alignerr; Brisbane; Remote; AUD 96,000 - 179,000; Part time

Job summary

Alignerr is seeking a Principal Clinical Scientist to shape how AI understands biomedical evidence. This fully remote hourly contract role demands senior-level rigor in clinical trial design and regulatory science for regulator-ready AI training data.

You will review protocols and results, ensure regulatory relevance, and provide structured feedback to improve AI reasoning about clinical data. Flexible hours suit experienced scientists seeking meaningful, high-impact work.

Qualifications

• Senior clinical scientist with hands-on experience designing clinical trial protocols for regulatory submission.
• Deep expertise interpreting clinical data for major regulatory agencies (FDA, EMA, or equivalent).
• Strong command of clinical research methodology and translational science.

Responsibilities

• Design and review clinical trial protocols used to generate regulator-ready datasets for AI training.
• Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance.
• Evaluate AI-generated clinical analyses for scientific soundness and regulatory alignment.
• Provide expert structured feedback to improve how AI models reason about trial data, endpoints, and outcomes.
• Work independently and asynchronously — fully on your own schedule.

Skills

Clinical trial design

Regulatory science

Biostatistics

AI in healthcare

Job description

Principal Clinical Scientist (AI Training)

About The Role

What if your career-long expertise in clinical trial design and regulatory science could directly shape how AI understands and reasons about biomedical evidence? We're looking for a Principal Clinical Scientist to bring senior-level rigor to cutting-edge AI research — ensuring the clinical knowledge embedded in next-generation AI systems meets the standards expected in real-world regulatory submissions.

This is a fully remote, flexible contract role built for experienced clinical scientists who want to do meaningful work at the frontier of AI and medicine. No prior AI background needed — just deep domain expertise and a commitment to scientific quality.

• Organization: Alignerr
• Type: Hourly Contract
• Location: Remote
• Commitment: 10–40 hours/week

What You'll Do

• Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training
• Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance
• Evaluate AI-generated clinical analyses for scientific soundness and alignment with FDA, EMA, or equivalent regulatory expectations
• Provide expert structured feedback to improve how AI models reason about clinical trial data, endpoints, and outcomes
• Work independently and asynchronously — fully on your own schedule

Who You Are

• Senior clinical scientist with hands-on experience designing clinical trial protocols for regulatory submission
• Deep expertise interpreting clinical data for major regulatory agencies (FDA, EMA, or equivalent)
• Strong command of clinical research methodology, biostatistics, or translational science
• Naturally rigorous and detail-oriented — you hold clinical evidence to the highest standard
• Clear and concise written communicator who can document reasoning and feedback effectively
• Self-motivated and reliable when working independently

Nice to Have

• Prior experience with data annotation, data quality frameworks, or evaluation systems
• Background in pharmacology, oncology, rare disease, or other specialized therapeutic areas
• Familiarity with AI tools or scientific evaluation workflows
• Experience in medical writing, regulatory affairs, or clinical operations

Why Join Us

• Work directly on frontier AI systems shaping the future of clinical and biomedical research
• Fully remote and flexible — work when and where it suits you
• Freelance autonomy with the structure of meaningful, high-impact work
• Influence how AI understands, evaluates, and reasons about real-world clinical evidence
• Collaborate with world-leading AI research teams and labs
• Potential for ongoing work and contract extension as new projects launch