Principal Clinical Scientist

Alignerr; Adelaide; Remote; AUD 235,000 - 353,000; Part time

Job summary

Alignerr is seeking a Principal Clinical Scientist to bring senior-level clinical rigor to AI development. You will design and review regulatory-ready trial protocols and audit clinical data powering AI systems, ensuring accuracy and regulatory alignment.

You will work remotely on your own schedule, contributing expert feedback to improve AI reasoning about clinical outcomes and establishing data quality standards across AI research workflows.

Qualifications

• Experience designing protocols for regulatory submission.
• Ability to interpret clinical data for FDA/EMA purposes.
• Strong biostatistics and study methodology knowledge.
• Ability to translate complex clinical concepts into actionable feedback.

Responsibilities

• Design and review clinical trial protocols for regulator-ready datasets for AI training.
• Interpret and audit clinical trial results for accuracy and regulatory relevance.
• Evaluate AI-generated clinical analyses for scientific soundness and regulatory alignment.
• Identify gaps in AI model reasoning and provide expert corrective feedback.
• Help establish quality standards for clinical data used across AI research workflows.
• Work independently and asynchronously.

Skills

Clinical trial design

Regulatory submissions

Data interpretation

Regulatory standards

Biostatistics

Clear communication

Education

Master’s or PhD in clinical science/biostatistics

Job description

Principal Clinical Scientist (AI Training)

About The Role

What if your expertise in clinical trial design and regulatory science could directly shape how AI reasons about medical evidence for researchers and clinicians worldwide?

We're looking for a Principal Clinical Scientist to bring senior-level clinical rigor to cutting-edge AI development. You'll work with leading AI research teams to ensure that the clinical data powering next-generation AI systems meets the same standards expected in real-world regulatory submissions.

This is a fully remote, flexible contract role built for experienced clinical scientists who want to do meaningful work on their own terms.

• Organization: Alignerr
• Type: Hourly Contract
• Location: Remote
• Commitment: 10–40 hours/week

What You'll Do

• Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training
• Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance
• Evaluate AI-generated clinical analyses for scientific soundness and alignment with regulatory expectations
• Identify gaps in how AI models reason about clinical outcomes and provide expert corrective feedback
• Help establish quality standards for clinical data used across AI research workflows
• Work independently and asynchronously — fully on your own schedule

Who You Are

• Senior-level clinical scientist with hands-on experience designing protocols for regulatory submission
• Deep expertise interpreting clinical data for agencies such as the FDA, EMA, or equivalent regulatory bodies
• Strong grounding in clinical research methodology, biostatistics, or translational science
• Naturally rigorous — you hold clinical data to the highest standards of accuracy and consistency
• Clear communicator who can translate complex clinical concepts into structured, actionable feedback

Nice to Have

• Prior experience with data annotation, data quality review, or AI evaluation workflows
• Background in pharmacovigilance, medical affairs, or clinical operations
• Familiarity with AI tools or machine learning systems in a biomedical context
• Experience contributing to cross-functional or distributed research teams

Why Join Us

• Work directly on frontier AI systems shaping the future of clinical and biomedical research
• Fully remote and flexible — work when and where it suits you
• Freelance autonomy with the structure of meaningful, expert-level work
• Influence how AI understands, evaluates, and communicates real-world clinical evidence
• Collaborate with leading AI research labs and scientists from around the world
• Potential for ongoing work and contract extension as new projects launch