Clinical Bioinformatician (Grade 4)

LifeStrands Genomics (Australia) Pty Ltd; Melbourne; On-site; AUD 110,000 - 170,000; Full time

Job summary

LifeStrands Genomics Australia Pty Ltd is seeking a Clinical Bioinformatician to develop, validate, and maintain bioinformatics pipelines supporting multiomic testing in an accredited diagnostic environment. You will work with lab, clinical, and IT teams to ensure timely, accurate genomic results that inform patient care.

The role emphasizes implementing new technologies, biomarkers, and compliant data governance, with a focus on data integrity and patient safety within regulatory frameworks.

Qualifications

• Postgraduate qualification (Master’s or PhD) in bioinformatics or related discipline, or equivalent relevant experience.
• Knowledge of molecular biology, cancer genomics, NGS technologies and genomic data analysis.
• Programming proficiency in R, shell scripting and at least one additional language; familiarity with APIs and common genomic file formats.
• Experience with Linux/Unix and version control systems, preferably Git/GitHub.
• Understanding of clinical diagnostic testing, analytical performance, data integrity and patient safety.
• Strong problem-solving, troubleshooting, documentation and communication skills.

Responsibilities

• Develop, maintain and troubleshoot software, scripts and pipelines for genomic and transcriptomic analysis.
• Support integration of sequencing platforms, LIMS, bioinformatics applications and reporting systems.
• Contribute to the implementation of new technologies, biomarkers and testing methodologies.
• Validate and verify bioinformatics pipelines before clinical implementation and following relevant changes.
• Evaluate analytical performance and monitor quality metrics to identify issues or trends.
• Assess and document the impact of software, pipeline, database and infrastructure changes.
• Participate in quality assurance, risk assessments and continuous improvement.
• Develop and maintain SOPs, validation records, technical documentation and training materials.
• Collaborate with laboratory, clinical, scientific, IT and management teams to support efficient molecular testing.
• Communicate technical findings, limitations and recommendations to multidisciplinary audiences.
• Maintain professional competence through ongoing development and engagement with technical and regulatory advances.

Skills

R programming

Shell scripting

Git/GitHub

Molecular biology

Cancer genomics

Education

Master’s or PhD in bioinformatics

Tools

LIMS

APIs

Cloud computing

Job description

LifeStrands Genomics (Australia) Pty Ltd – Mount Waverley VIC

Are you passionate about using genomics to advance cancer precision medicine? Are you excited by developing and implementing robust, innovative bioinformatics solutions that underpin high-quality molecular diagnostic testing?

At LifeStrands Genomics Australia, you’ll have the opportunity to apply your computational and scientific expertise to meaningful clinical applications, helping deliver accurate, reliable and timely genomic results that inform patient care.

Join our team and help shape the future of cancer diagnostics through innovation, scientific excellence and clinical impact.

PLEASE NOTE: THIS POSITION IS OPEN ONLY TO AUSTRALIAN CITIZENS AND PERMANENT RESIDENTS CURRENTLY RESIDING IN AUSTRALIA. APPLICATIONS FROM OVERSEAS WILL NOT BE CONSIDERED.

Position purpose

We are seeking a Clinical Bioinformatician to develop, validate, maintain and improve bioinformatics software and analytical pipelines supporting multiomic testing at LifeStrands Genomics Australia (LSGA). Working with laboratory, scientific and clinical staff, the role supports accurate, reliable, timely and clinically relevant results within an accredited diagnostic environment.

The position also supports new technology implementation, analytical quality monitoring and compliance with applicable accreditation, regulatory, privacy and data governance requirements.

Essential qualifications and experience

• Postgraduate qualification (Master’s or PhD) in bioinformatics or a related discipline, or equivalent relevant experience.
• Knowledge of molecular biology, cancer genomics, NGS technologies and genomic data analysis.
• Programming proficiency in R, shell scripting and at least one additional language; familiarity with APIs and common genomic file formats.
• Experience with Linux/Unix and version control systems, preferably Git/GitHub.
• Understanding of clinical diagnostic testing, analytical performance, data integrity and patient safety.
• Strong problem-solving, troubleshooting, documentation and communication skills.

Highly desirable qualifications and experience

• Experience in an accredited clinical laboratory or regulated diagnostic environment.
• Experience developing, validating or maintaining genomic or transcriptomic bioinformatics pipelines.
• Experience with cloud computing, high-performance computing or scalable data processing.
• Knowledge of software validation, quality management, risk assessment and change control.
• Familiarity with NATA, NPAAC, ISO 15189 and other relevant regulatory requirements.
• Understanding of cybersecurity, privacy, data governance and healthcare data exchange standards.
• Experience with automated testing, software deployment, monitoring, backup or disaster recovery.

Roles and responsibilities

Bioinformatics development and implementation

• Develop, maintain and troubleshoot software, scripts and pipelines for genomic and transcriptomic analysis.
• Support integration of sequencing platforms, LIMS, bioinformatics applications and reporting systems.
• Contribute to the implementation of new technologies, biomarkers and testing methodologies.

Validation and quality assurance

• Validate and verify bioinformatics pipelines before clinical implementation and following relevant changes.
• Evaluate analytical performance and monitor quality metrics to identify issues or trends.
• Assess and document the impact of software, pipeline, database and infrastructure changes.
• Participate in quality assurance, nonconformance investigations, risk assessments and continuous improvement.

Compliance and documentation

• Support compliance with applicable NATA, NPAAC, ISO and other regulatory requirements.
• Develop and maintain SOPs, validation records, technical documentation and training materials.
• Support data integrity, cybersecurity, confidentiality, backup and recovery requirements.
• Identify and escalte risks affecting analytical performance, result integrity or patient care.

Collaboration and service delivery

• Collaborate with laboratory, clinical, scientific, IT and management teams to support efficient molecular testing.
• Communicate technical findings, limitations and recommendations to multidisciplinary audiences.
• Maintain professional competence through ongoing development and engagement with relevant technical and regulatory advances.
• Uphold LSGA’s commitment to patient safety, high-quality results, excellent customer service and timely turnaround.