Analytical Development Internship in Analytical Sciences (6 months, Basel)

F. Hoffmann-La Roche AG; Schweiz; Vor Ort; EUR 22.000 - 36.000; Vollzeit

Zusammenfassung

F. Hoffmann-La Roche AG in Basel is offering an Analytical Development Intern position focused on LC‑MS.

You will contribute to analytical project work from the outset, supporting characterization, quantification, and stability assessment of drug products using mass spectrometry‑based methods. You will gain hands-on experience in a modern analytical lab, work with cross‑functional teams, and develop expertise in LC‑MS/ESI‑MS within pharmaceutical analytics.

Qualifikationen

• Enrolled in BSc/MSc Analytical Biology or Pharmaceutical Sciences, or recently completed a Master’s in these fields.
• Project not suitable for Bachelor/Master thesis.
• Interest in LC‑MS/ESI‑MS analytics and pharmaceutical analytics.

Aufgaben

• Plan and perform analytical studies to support development and characterization of drug products using LC‑MS‑based methods.
• Support development and application of LC–MS methods for analysis of drug products.
• Carry out physico-chemical analyses using LC‑MS, HPLC/UPLC and complementary chromatographic methods.
• Assist in sample preparation and troubleshooting of LC‑MS instruments and workflows.
• Ensure data integrity and comprehensive documentation per ALCOA+ standards.
• Collaborate with scientists and cross‑functional teams to support analytical strategies for parenteral drug products.

Kenntnisse

Mass spectrometry

LC-MS

Sample preparation

Data processing

Ausbildung

Bachelor’s or Master’s in Analytical Biology

Master’s in Analytical Biology/Pharmaceutical Sciences

Tools

LC-MS

HPLC/UPLC

Data Systems (Waters/Thermo/Bruker)

Jobbeschreibung

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

The Analytical Development Biochemistry group, located in Basel, is an integral component of how we innovate healthcare through the invention of differentiated medicines for treating diseases of current unmet medical need. This internship program integrates seamlessly into European-based University degree program and therefore we offer the most talented students the opportunity to gain valuable work experience with us.

The Opportunity

As an Analytical Development Intern in Analytical Sciences with a focus on LC‑MS, you will actively contribute to analytical project work from the very beginning. You will support the characterization, quantification, and stability assessment of drug products and related samples using state‑of‑the‑art mass spectrometry‑based analytical methods.

Your responsibilities and learning opportunities include:

• Plan and perform analytical studies (e.g., peptide mapping) to support the development and characterization of pharmaceutical drug products, with a particular focus on LC‑MS‑based methods.
• Support the development, optimization, and application of liquid chromatography–mass spectrometry methods for the analysis of drug products.
• Carry out physico-chemical analyses of development and non-manufacturing-grade samples using modern analytical techniques, including LC‑MS, HPLC/UPLC, and complementary chromatographic methods.
• Assist in sample preparation (e.g., enzymatic digests) and the optimisation/troubleshooting of LC‑MS instruments and data processing workflows.
• Ensure the integrity of data and take full ownership of comprehensive documentation for all analytical studies in compliance with internal quality standards (ALCOA+ principles).
• Collaborate with experienced scientists and cross‑functional project teams to support analytical strategies for the development of parenteral drug products.
• Apply analytical thinking and problem‑solving skills to improve experimental workflows, optimise methods, and support efficient laboratory processes.
• Gain hands‑on experience in a modern analytical laboratory environment and develop a deeper understanding of mass spectrometry‑based analytics in pharmaceutical development.
• Be part of a team committed to innovation, collaboration, and developing patient‑centric solutions that make a meaningful impact in healthcare.

Who You Are

You are currently enrolled in a Bachelor’s or Master’s program in Analytical Biology, Pharmaceutical Sciences, or a related field—or have graduated with a Master’s degree in one of these disciplines within the past 12months prior to the start date. Project is not suitable for Bachelor / Master thesis. You are motivated to increase and share your theoretical and practical knowledge on this emerging and exciting field of liquid chromatography–mass spectrometry (LC‑MS) / electrospray ionization mass spectrometry (ESI‑MS) and you are an enthusiast of new technologies and you easily show engagement with people. Experiences in sample preparation of biomolecules and in mass spectrometry in general are considered a plus. You are an enthusiastic and motivated individual with a strong interest in pharmaceutical analytics and modern instrumental analysis.

Interest in Analytical Sciences

You have a strong interest in pharmaceutical analysis, especially in chromatographic and mass spectrometry‑based methods such as LC‑MS or LC‑MS/MS.

Analytical Competence

You have a solid understanding of liquid chromatography (HPLC/UPLC) and mass spectrometry (LC‑MS). Hands on experiences with LC systems, sample preparation, or Data Systems (e.g. Waters, Thermo, Bruker) is a strong asset.

Scientific Mindset

You enjoy working accurately and systematically, documenting your work carefully, and interpreting analytical data in a structured way.

Personal Strengths

You are self‑reliant, curious, solution‑oriented, and motivated to work in a collaborative and international team environment.

Communication Skills

You communicate clearly, enjoy teamwork, and are open to learning from experienced scientists.

Language Skills

You are fluent in written and spoken German. English language skills are an advantage.

Knowledge about Good Manufacturing Practice (GMP)

Knowledge about Good Manufacturing Practice (GMP) is a plus.

Start Date & Duration: Planned Start Date: Flexible, effective immediately or beginning of 2027. Duration: At least 6 months.

Non‑EU/EFTA Applicants: Due to regulatory requirements, non‑EU/EFTA citizens must remain enrolled at their university for the entire duration of the internship and must include an official certificate from their university confirming that the internship is a mandatory requirement of their study program.

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life‑changing healthcare solutions that make a global impact. Let’s build a healthier future, together.

Roche is an Equal Opportunity Employer. We believe it’s urgent to deliver medical solutions right now – even as we develop innovations for the future. We are passionate about transforming patients’ lives. We are courageous in both decision and action. And we believe that good business means a better world. That is why we come to work each day. We commit ourselves to scientific rigor, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow. We are proud of who we are, what we do, and how we do it. We are many, working as one across functions, across companies, and across the world. We are Roche.