Clinical Research Manager (Crm)

Merck; Buenos Aires; On-site; ARS 900,000 - 1,300,000; Full time

Job summary

Merck is seeking a Clinical Research Manager (CRM) to oversee country-level clinical studies from start-up to close-out. You will coordinate investigators, sites, vendors, and internal teams to ensure delivery within timelines and quality standards, while navigating regulatory requirements and global study expectations.

The role emphasizes risk management, stakeholder influence, and continuous improvement across Clinical Operations, with travel up to 20–30% locally and internationally.

Qualifications

• Bachelor's degree in Life Sciences, Health Sciences, or related field.
• More than 6 years of relevant experience in clinical research.
• Preferred experience as a Clinical Research Associate with at least 3 years of monitoring experience.
• Oncology experience is preferred.
• Advanced English proficiency for global cross-functional collaboration.
• Travel: 20%-30% locally & internationally.

Responsibilities

• Lead and oversee the operational execution of assigned clinical studies.
• Ensure activities are delivered in line with timelines, quality, protocols, GCP, and local regulations.
• Coordinate with investigators, sites, CRAs, vendors, and internal study teams.
• Monitor study performance using clinical systems, dashboards, and metrics.
• Identify risks and implement mitigation plans across regulatory, quality, or timeline domains.
• Support sites in addressing operational challenges, including recruitment and performance.

Skills

Clinical ops

GCP knowledge

Regulatory

Stakeholder mgmt

Project leadership

English proficiency

Education

Bachelor's degree in Life Sciences

Job description

Job Description

The Clinical Research Manager (CRM) is responsible for ensuring the successful execution of assigned clinical studies at the country level, from study start-up through close-out.

The CRM coordinates investigators, clinical research sites, vendors, Clinical Research Associates (CRAs), and internal cross-functional teams to ensure studies are delivered in accordance with agreed timelines, quality standards, study protocols, Good Clinical Practice (GCP), and applicable regulatory requirements.

This role serves as a key connection between local clinical operations and global study teams, proactively managing risks, resolving operational challenges, and driving effective study execution.

Key Responsibilities

• Lead and oversee the operational execution of assigned clinical studies.
• Ensure study activities are delivered in accordance with timelines, quality expectations, protocols, GCP, and applicable local regulatory requirements.
• Coordinate and collaborate with investigators, research sites, CRAs, vendors, and internal study teams.
• Monitor study performance through clinical systems, dashboards, metrics, and data-driven insights.
• Proactively identify operational, regulatory, quality, financial, or timeline risks and implement appropriate mitigation plans.
• Exercise sound judgment and make decisions within the scope of assigned responsibilities, escalating issues when appropriate.
• Support sites and study teams in addressing operational challenges, including patient recruitment, site performance, resource constraints, compliance matters, and stakeholder alignment.
• Build strong relationships across local, regional, and global teams and effectively influence stakeholders without direct authority.
• Support the adoption of new processes, technologies, digital solutions, and evolving ways of working.
• Contribute to continuous improvement initiatives across Clinical Operations.

Required Qualifications

• Bachelor's degree in Life Sciences, Health Sciences, or a related field.
• More than 6 years of relevant experience in clinical research.
• Previous experience as a Clinical Research Associate is strongly preferred, ideally including at least 3 years of clinical monitoring experience.
• Oncology Experience is preferred.
• Advanced English proficiency, with the ability to communicate effectively in a global and cross-functional environment.
• Strong knowledge of clinical research operations, Good Clinical Practice (GCP), and applicable local regulations.
• Demonstrated experience working effectively with investigators, clinical research sites, vendors, and cross-functional teams.
• Travel: 20%-30% locally & internationally.

The ability to build trusted relationships, influence outcomes, negotiate effectively, and navigate complex stakeholder environments is critical to success in this role.

Key Capabilities

Accountability & Decision Making

• Takes ownership of outcomes for assigned clinical studies.
• Demonstrates autonomy and sound judgment within the scope of responsibility.
• Effectively determines when issues should be resolved independently and when escalation is required.

Digital & Data Proficiency

• Effectively uses clinical systems, dashboards, performance metrics, and data to manage study execution.
• Leverages insights to anticipate risks, identify trends, and support informed decision-making.
• Demonstrates curiosity and openness toward automation, digital solutions, and company-approved AI-enabled tools.

Change Management

• Actively contributes to and supports change initiatives.
• Facilitates adoption of new tools, processes, and ways of working.
• Supports colleagues and stakeholders in successfully navigating change.

Critical Thinking

• Evaluates complex issues from multiple perspectives.
• Assesses risks, implications, and trade-offs before making decisions.
• Develops pragmatic solutions that balance operational, regulatory, quality, and business considerations.

Agile & Flexible Mindset

• Adapts effectively to evolving study priorities and business needs.
• Operates successfully in dynamic, global, cross-functional, and virtual environments.
• Demonstrates resilience and flexibility when managing ambiguity or unexpected challenges.

Risk-Based Decision Making & Leadership

• Proactively identifies operational, regulatory, quality, financial, and timeline-related risks.
• Prioritizes actions based on potential impact to the study, patients, sites, and business.
• Applies a structured, risk-based approach to decision-making and problem-solving.

Relationship & Stakeholder Management

• Builds strong and trusted relationships with investigators, clinical sites, vendors, and internal stakeholders.
• Influences effectively without relying on formal authority.
• Navigates complex negotiations, competing priorities, and conflict constructively.
• Demonstrates empathy, diplomacy, and strong written and verbal communication skills.