Clinical Variant Scientist - Genomics & AI

National Reference Laboratory (NRL); Abu Dhabi; On-site; AED 300,000 - 500,000; Full time

Job summary

National Reference Laboratory (NRL) in the United Arab Emirates is seeking a Variant Scientist to identify and interpret genetic variants for NGS-based testing across service lines. You will collaborate with geneticists, bioinformaticians, and clinicians to apply insights to patient care.

The role requires expertise in curation, interpretation, and reporting, with up-to-date knowledge of ACMG/AMP guidelines and databases. A regulated lab environment and timely delivery of results are essential.

Qualifications

• Advanced degree in molecular genetics or related field with clinical NGS experience.
• Experience in variant curation and interpretation for somatic oncology preferred.
• Ability to write clear, concise clinical reports.

Responsibilities

• Perform end-to-end clinical variant interpretation for NGS-based testing (somatic and/or germline, depending on service line).
• Curate and classify variants using accepted frameworks (ACMG/AMP, AMP/ASCO/CAP; tumor-type context and evidence grading).
• Draft clear, clinically actionable molecular report narratives
• Maintain and contribute to an internal knowledgebase (variant assertions, evidence summaries, literature updates, version control).
• Support validation/verification of new assays, updates to pipelines/panels, and post-launch performance monitoring.
• Participate in quality management activities (CAP/ISO documentation, audits, EQA/PT responses, CAPA/OVR as needed).
• Communicate effectively with laboratory and clinical stakeholders to resolve interpretation queries and support case discussions.

Skills

Clinical NGS variant curation

Variant interpretation

ACMG/AMP standards

Clinical reporting

Laboratory workflows

Attention to detail

Timely delivery (TAT)

Education

MSc/PhD in Molecular Genetics/Genomics/Bioinformatics/Biomedical Science or related field

Tools

ACMG/AMP guidelines

ClinVar/gnomAD/COSMIC databases

NGS data review concepts

Job description

National Reference Laboratory (NRL) in the United Arab Emirates is seeking a Variant Scientist to identify and interpret genetic variants for NGS-based testing across service lines. You will collaborate with geneticists, bioinformaticians, and clinicians to apply insights to patient care.

The role requires expertise in curation, interpretation, and reporting, with up-to-date knowledge of ACMG/AMP guidelines and databases. A regulated lab environment and timely delivery of results are essential.