Senior Pharmacologist — Relocation Support, Drug Discovery

Placements24; Sandton; Hybrid; ZAR 900,000 - 1,400,000; Full time

Benefits offered by this job

Medical, dental, retirement plans

Relocation assistance

Job summary

Placements24 in Sandton, Gauteng, invites a Senior Pharmacologist to lead preclinical pharmacology activities within our innovative drug discovery program. The role focuses on designing and executing in vitro and in vivo studies to evaluate efficacy, safety, and mechanisms of action of novel candidates.

You will collaborate with medicinal chemistry, biology, toxicology, and DMPK teams, translate findings to clinical development, mentor junior scientists, and help prepare regulatory submissions

Qualifications

• PhD in Pharmacology, Toxicology, or related life science.
• Minimum 5 years post-doctoral or industry experience in drug discovery.
• Proven ability to design preclinical pharmacology studies (in vitro/in vivo).

Responsibilities

• Design, execute, and interpret in vitro and in vivo pharmacology studies.
• Develop and validate assays and models relevant to disease areas.
• Analyze study data with statistical methods and present findings.
• Contribute to regulatory documents (e.g., IND filings) and scientific publications.
• Collaborate with multidisciplinary teams, including medicinal chemistry, biology, toxicology, and DMPK.
• Stay abreast of scientific literature and emerging trends in pharmacology.
• Mentor junior scientists and contribute to the strategic direction of the pharmacology department.
• Ensure compliance with GLP, ethics, and animal welfare regulations.
• Troubleshoot experimental procedures and identify solutions to research challenges.

Skills

In vitro / in vivo pharmacology

Data analysis with statistics

Scientific publication ability

Team collaboration

Education

PhD in Pharmacology, Toxicology, or related life science

Tools

Statistical software

Job description

Placements24 in Sandton, Gauteng, invites a Senior Pharmacologist to lead preclinical pharmacology activities within our innovative drug discovery program. The role focuses on designing and executing in vitro and in vivo studies to evaluate efficacy, safety, and mechanisms of action of novel candidates.

You will collaborate with medicinal chemistry, biology, toxicology, and DMPK teams, translate findings to clinical development, mentor junior scientists, and help prepare regulatory submissions