Senior Computational Biologist, Systems Biology - Omics

Placements24; Paarl; On-site; ZAR 1,200,000 - 1,900,000; Full time

Benefits offered by this job

Competitive salary package

Health insurance and retirement plan

Professional development opportunities

Conference participation

Job summary

Placements24 seeks a Senior Computational Biologist in Paarl, Western Cape to lead computational biology initiatives. You will work on multi-omics data integration, build models, and guide drug discovery through network and pathway analyses.

You will collaborate with biologists, chemists, and clinicians, develop custom tools, and contribute to publications. A PhD and 5+ years in the field are expected, with strong programming skills in Python or R.

Qualifications

• Ph.D. in Computational Biology, Systems Biology, Bioinformatics, Computer Science, or related quantitative field.
• Minimum of 5 years post-doctoral or industry experience in computational biology.
• Demonstrated expertise in systems biology approaches, including network analysis and pathway modeling.
• Proficiency in Python or R and related bioinformatics and statistical packages.
• Experience with large-scale omics data (genomics, transcriptomics, proteomics).
• Familiarity with biological databases and pathway knowledge bases (e.g., KEGG, Gene Ontology, STRING).
• Strong understanding of molecular biology, cell biology, and disease mechanisms.
• Excellent analytical and problem-solving skills.
• Strong communication and collaboration abilities.

Responsibilities

• Develop and apply computational models to analyze complex biological systems.
• Integrate and analyze multi-omics data from various experimental sources.
• Perform pathway analysis, network construction, and systems-level interpretation of biological data.
• Identify key molecular players and mechanisms relevant to disease progression and drug response.
• Collaborate with experimental biologists, chemists, and clinicians to design studies and interpret results.
• Develop custom scripts and software tools to facilitate computational biology workflows.
• Stay abreast of the latest advancements in systems biology and computational biology.
• Contribute to preparation of scientific publications and grant proposals.
• Present research findings to internal teams and at scientific conferences.

Skills

Systems biology

Network analysis

Pathway modeling

Multi-omics analysis

Statistical modeling

Education

PhD in Computational Biology

Tools

Python

R

Bioinformatics packages

Job description

Placements24 seeks a Senior Computational Biologist in Paarl, Western Cape to lead computational biology initiatives. You will work on multi-omics data integration, build models, and guide drug discovery through network and pathway analyses.

You will collaborate with biologists, chemists, and clinicians, develop custom tools, and contribute to publications. A PhD and 5+ years in the field are expected, with strong programming skills in Python or R.