Senior Clinical Data Manager

Placements24; Soweto; Hybrid; ZAR 900,000 - 1,400,000; Full time

Benefits offered by this job

Fully remote work

Career development opportunities

Job summary

Placements24 seeks a Senior Clinical Data Manager to lead data management for global clinical trials in a fully remote role.

You will design and validate databases, implement DM plans, and ensure data quality and regulatory compliance from your home office, with support for Soweto-based professionals.

Qualifications

• Bachelor's degree in Computer Science, Statistics, Life Sciences, or Nursing.
• 7+ years of clinical data management experience, with 2+ in lead roles.
• Extensive experience with EDC systems (Medidata Rave, Oracle Clinical).
• Strong knowledge of CDISC standards (SDTM/ADaM).
• Excellent remote collaboration and project management skills.

Responsibilities

• Oversee design, development, and validation of clinical databases using EDC.
• Develop data management plans and SOPs.
• Lead data cleaning, including queries and resolutions.
• Manage data review meetings and ensure timely database lock.
• Ensure compliance with GCP, FDA/EMA guidelines and company policies.
• Mentor junior data management staff.

Skills

EDC systems

SQL

CDISC SDTM/ADaM

Communication

Project management

Mentoring

Education

Bachelor's degree

Tools

Medidata Rave

Oracle Clinical

Job description

About the Role

Our client is seeking an experienced and highly organized Senior Clinical Data Manager to lead their data management activities for global clinical trials. This fully remote position allows you to manage critical data processes from your home office, ensuring the accuracy, completeness, and integrity of clinical trial data. You will be responsible for database design, data validation, and ensuring compliance with regulatory standards. This role is pivotal in supporting the timely completion of clinical studies and contributing to the development of life‑saving therapies, offering a significant impact on research outcomes from anywhere, including support for professionals based around Soweto .

Key Responsibilities

• Oversee the design, development, and validation of clinical databases using EDC systems.
• Develop and implement data management plans and standard operating procedures (SOPs).
• Lead data cleaning activities, including query generation and resolution, to ensure data accuracy and consistency.
• Manage data review meetings and ensure timely database lock according to study timelines.
• Ensure compliance with GCP, regulatory guidelines (e.g., FDA, EMA), and company policies.
• Mentor and guide junior data management staff and provide technical expertise.

Requirements

• Bachelor's degree in a relevant field such as Computer Science, Statistics, Life Sciences, or Nursing.
• Minimum of 7 years of experience in clinical data management, with at least 2 years in a senior or lead role.
• Extensive experience with Electronic Data Capture (EDC) systems (e.g., Medidata Rave, Oracle Clinical).
• Strong understanding of clinical trial processes, database design, and data validation techniques.
• Proficiency in SQL and knowledge of CDISC data standards (SDTM, ADaM).
• Excellent communication, problem-solving, and project management skills for remote collaboration.

Benefits

• Competitive annual salary and comprehensive benefits package.
• Fully remote work flexibility with supportive technology and resources.
• Annual bonus and performance-based incentives.
• Opportunities for professional development and industry certifications.
• Work on impactful clinical trials that contribute to global health advancements, offering a rewarding career from anywhere in Gauteng .