Senior Biophysicist - Molecular Interactions Lab

Placements24; Kimberley; On-site; ZAR 1,200,000 - 2,400,000; Full time

Benefits offered by this job

Relocation assistance

Professional development

State-of-the-art instruments

Collaborative environment

Job summary

Placements24 is recruiting a Senior Biophysicist to lead the Molecular Interactions Laboratory in Kimberley, Northern Cape, ZA. The role focuses on probing physical principles of biological macromolecules, designing experiments (SPR, ITC, MST, cryo-EM), and guiding a research program toward therapeutic innovations.

You will mentor junior scientists, collaborate with biochemists and pharmacologists, publish findings in high-impact journals, and manage lab operations and funding proposals while

Qualifications

• PhD in Biophysics or a related field.
• 8+ years of post-doctoral research in biophysics.
• Experience designing and executing diverse biophysical experiments.
• Strong publication record in reputable journals.
• Excellent leadership and mentorship abilities.

Responsibilities

• Lead research into physical properties and interactions of biological macromolecules.
• Design, implement, and optimize biophysical experiments (SPR, ITC, MST, cryo-EM).
• Analyze and interpret biophysical data and model molecular mechanisms.
• Collaborate with biochemists, structural biologists, and pharmacologists.
• Publish findings and present at international conferences.
• Mentor junior researchers and manage lab operations and budgets.
• Contribute to grant proposals and secure funding.
• Ensure adherence to safety protocols in the laboratory.

Skills

Biophysics

Molecular interactions

Data analysis

Statistical modeling

Leadership

Mentorship

Education

PhD in Biophysics or related field

Tools

SPR

ITC

MST

cryo-EM

X-ray crystallography

Computational modeling software

Job description

About the Role

Our client, a renowned research institute dedicated to advancing our understanding of biological systems, is seeking a Senior Biophysicist to lead their Molecular Interactions Laboratory in Kimberley, Northern Cape, ZA. This pivotal role involves investigating the physical principles governing biological molecules and their interactions, utilizing cutting-edge experimental techniques. You will lead research projects, mentor junior scientists, and contribute to the development of novel therapeutic strategies. This is an outstanding opportunity to make significant contributions to the fields of molecular biology and drug discovery within our Kimberley, Northern Cape, ZA-based advanced research facility.

Key Responsibilities

• Lead research into the physical properties and interactions of biological macromolecules.
• Design, implement, and optimize biophysical experiments using techniques such as SPR, ITC, MST, cryo-EM, and spectroscopy.
• Analyze and interpret complex biophysical data to elucidate molecular mechanisms.
• Develop and apply computational models to understand molecular dynamics and interactions.
• Collaborate with biochemists, structural biologists, and pharmacologists to integrate findings.
• Publish research results in high-impact scientific journals and present at international conferences.
• Mentor and supervise junior researchers, postdoctoral fellows, and technical staff.
• Manage laboratory resources, equipment, and budgets efficiently.
• Contribute to grant proposals and secure research funding.
• Ensure adherence to safety protocols and best practices in the laboratory.

Requirements

• Ph.D. in Biophysics, Biochemistry, Physical Chemistry, or a related field.
• Minimum of 8 years of post-doctoral research experience in biophysics, with a focus on molecular interactions.
• Demonstrated expertise in designing and executing a range of biophysical experiments.
• Proficiency in data analysis and interpretation, including statistical modeling.
• Experience with structural biology techniques (e.g., X-ray crystallography, cryo-EM) is a plus.
• Knowledge of computational biophysics and molecular modeling software.
• Strong publication record in reputable journals.
• Excellent leadership, mentorship, and communication skills.
• Proven ability to manage research projects and laboratory operations.
• Ability to work collaboratively and effectively within a research team located in Kimberley, Northern Cape, ZA.

Benefits

• Our client offers a highly competitive salary, comprehensive benefits including health, dental, and vision insurance, a retirement savings plan, and relocation assistance to Kimberley, Northern Cape, ZA.
• We provide exceptional opportunities for professional development, access to state-of-the‑art instrumentation, and a collaborative research environment.
• Join our innovative team in Kimberley, Northern Cape, ZA and contribute to significant advancements in understanding the fundamental workings of biological systems.