Research Scientist - Molecular Diagnostics

Placements24; Gauteng; On-site; ZAR 900,000 - 1,300,000; Full time

Benefits offered by this job

Medical, dental, vision coverage

Generous leave allowance

Conferences and workshops

Career development opportunities

Advanced lab equipment access

Wellness programs

Collaborative team culture

Job summary

Placements24 is seeking a Research Scientist to join the Molecular Diagnostics team in Tembisa, Gauteng. You will design, develop, and validate novel diagnostic assays for early detection and monitoring of diseases.

Lead experiments, analyse data, and contribute to regulatory submissions, while maintaining GLP-compliant laboratory records in a state-of-the-art facility.

Qualifications

• PhD or MSc in Molecular Biology, Biochemistry, Genetics, or related life science field.
• 4+ years hands-on experience in developing and validating molecular diagnostic assays.
• Extensive knowledge of molecular biology techniques (PCR, qPCR, nucleic acid isolation).

Responsibilities

• Develop and optimise molecular diagnostic assays (PCR, qPCR, ddPCR, NGS).
• Design experiments to validate assay performance (sensitivity, specificity, accuracy).
• Analyse data, interpret results, and generate reports.
• Collaborate with cross-functional teams to progress projects.

Skills

Molecular biology

PCR / qPCR

NGS

Data analysis

GLP compliance

Independent project mgmt

Education

PhD or MSc in Molecular Biology

Tools

PCR instruments

Nucleic acid isolation

Statistical software

Job description

About the Role

Our client, a leading pharmaceutical research and development company, is seeking a dedicated Research Scientist to join their innovative Molecular Diagnostics team in Tembisa, Gauteng. This critical role will involve the design, development, and validation of novel diagnostic assays for the early detection and monitoring of diseases. You will be at the forefront of scientific discovery, contributing to projects that aim to significantly improve patient outcomes through precise and timely diagnostic solutions. The role requires a deep understanding of molecular biology techniques and a passion for translating scientific findings into tangible diagnostic tools. You will be part of a highly collaborative team working in a state-of-the‑art laboratory environment. This position offers an exceptional opportunity to shape the future of diagnostics within a company committed to scientific excellence and global health.

Key Responsibilities

• Develop and optimise molecular diagnostic assays, including PCR, qPCR, ddPCR, and next‑generation sequencing (NGS) based methods.
• Design and execute experiments to validate assay performance, including sensitivity, specificity, accuracy, and reproducibility.
• Analyse experimental data, interpret results, and generate comprehensive reports.
• Troubleshoot and resolve technical issues that may arise during assay development and validation.
• Collaborate with cross‑functional teams, including product development, manufacturing, and clinical affairs, to ensure seamless project progression.
• Contribute to the preparation of regulatory submissions and scientific publications.
• Maintain accurate and detailed laboratory records in compliance with Good Laboratory Practices (GLP).
• Stay updated with the latest scientific literature and technological advancements in molecular diagnostics.
• Characterise and validate novel biomarkers for diagnostic applications.

Requirements

• Ph.D. or Master's degree in Molecular Biology, Biochemistry, Genetics, or a related life science discipline.
• Minimum of 4 years of hands‑on experience in developing and validating molecular diagnostic assays.
• Extensive knowledge and practical experience with various molecular biology techniques (PCR, qPCR, nucleic acid isolation, etc.).
• Experience with NGS library preparation and sequencing platforms is highly desirable.
• Proficiency in data analysis software and statistical methods.
• Strong understanding of assay principles and validation strategies.
• Excellent organisational, documentation, and record‑keeping skills.
• Ability to work independently and manage multiple projects simultaneously.
• Effective communication and presentation skills, both written and verbal.
• Experience working in a regulated environment (e.g., ISO 13485, CLIA) is an advantage.

Benefits

• Competitive annual salary and performance‑based bonuses.
• Comprehensive medical, dental, and vision coverage.
• Generous annual leave and public holiday allocation.
• Opportunities for continuous learning and professional growth, including workshops and conferences.
• Access to advanced laboratory equipment and resources.
• A supportive and dynamic team culture focused on innovation.
• Employee wellness programs and initiatives.
• Potential for long‑term career advancement within a growing organisation.