Principal Statistical Programmer (SAS & R) – Remote

Placements24; East London; Remote; ZAR 1,824,000 - 2,819,000; Full time

Job summary

Cytel Inc. is seeking a Senior/Principal Statistical Programmer to work remotely on sponsor-driven clinical programs, with autonomy in delivering high-quality analyses.

You will lead programming for SDTM/ADaM, define.xml, listings and tables, while ensuring compliance with FDA/ICH guidelines and contributing to study reports and regulatory submissions. Ideal candidates bring extensive SAS and R expertise, CDISC standards mastery, and prior CRO oversight experience, collaborating with

Qualifications

• Bachelor's degree in a quantitative field is preferred.
• 7+ years of experience as a Statistical Programmer in Biotech/Pharma.
• Strong SAS programming expertise for clinical development.
• Deep knowledge of CDISC standards (SDTM/ADaM/Define.xml).
• Experience supporting regulatory submissions with FDA/ICH interactions.
• Ability to work independently with minimal supervision.

Responsibilities

• Generate SDTM, ADaM specs, datasets, define.xml and reviewer's guide.
• Develop SAS programs to produce datasets, listings, tables and graphs.
• Deliver high-quality programming results and validate R/SAS outputs.
• Oversee CRO programmers to meet timelines and quality standards.
• Support clinical study reports, regulatory submissions and DSURs.

Skills

SAS programming

Leadership

Communication skills

Independent work

FDA/ICH knowledge

CDISC SDTM/ADaM

Education

Bachelor's degree in Computer Science/Data Science/Mathematics/Statistics

Tools

R

Python

Java

Shiny

Markdown

Unix/Linux

git

Job description

Cytel Inc. is seeking a Senior/Principal Statistical Programmer to work remotely on sponsor-driven clinical programs, with autonomy in delivering high-quality analyses.

You will lead programming for SDTM/ADaM, define.xml, listings and tables, while ensuring compliance with FDA/ICH guidelines and contributing to study reports and regulatory submissions. Ideal candidates bring extensive SAS and R expertise, CDISC standards mastery, and prior CRO oversight experience, collaborating with