Principal Data Scientist - Genomics

Placements24; Rustenburg; Hybrid; ZAR 1,800,000 - 3,000,000; Full time

Benefits offered by this job

Medical, dental, vision

Retirement plan

Relocation support

Professional growth opportunities

Flexible working

Job summary

Placements24 in Rustenburg, North West, is seeking a Principal Data Scientist to lead advanced ML and biomedical analytics initiatives. You will mentor junior scientists, shape data science strategy, and collaborate with genetics, clinical and software teams to translate complex datasets into actionable insights.

The role requires a PhD and 8+ years of life sciences data experience, deep Python/R expertise, and proven deployment of predictive models on large-scale genomic data.

Qualifications

• PhD in a quantitative field (Data Science, CS, Statistics or Bioinformatics).
• 8+ years hands-on data science experience in life sciences/healthcare.
• Proven track record deploying predictive models on complex biological data.
• Proficiency in Python or R and libraries (scikit-learn, TensorFlow, PyTorch, pandas, NumPy).
• Experience with large-scale data processing and SQL/NoSQL databases.

Responsibilities

• Develop, validate, and deploy advanced ML models for genomic data analysis.
• Lead exploration and interpretation of multi-modal data (genomics, transcriptomics, EHR).
• Design data mining and predictive modeling to identify biomarkers and targets.
• Collaborate with geneticists, bioinformaticians, clinicians, and engineers to deliver data-driven solutions.
• Mentor junior scientists and foster scientific rigor and excellence.
• Stay current with advancements in data science, genomics, and related fields.
• Communicate complex findings to technical and non-technical stakeholders.
• Contribute to IP through publications and patents.

Skills

Python

R

scikit-learn

TensorFlow

PyTorch

pandas

NumPy

ML engineering

Education

Ph.D. in Data Science / Computer Science / Statistics / Bioinformatics

Tools

SQL

NoSQL

Spark

Git

Job description

About the Role

Our client, a leader in applied genomics and personalized medicine, is seeking a highly accomplished Principal Data Scientist to join their innovative R&D team in Rustenburg, North West. This senior position is crucial for developing and implementing sophisticated analytical models and machine learning algorithms to extract deep insights from large-scale genomic and clinical datasets. You will play a key role in shaping the company's data science strategy, mentoring junior scientists, and driving research initiatives that translate complex biological data into actionable clinical insights. The ideal candidate possesses a strong academic background, extensive experience in data science within the life sciences sector, and a passion for leveraging cutting-edge computational techniques to solve challenging biological problems. This role offers an exceptional opportunity to make a significant impact on patient care and scientific understanding from our Rustenburg, North West location.

Key Responsibilities

• Develop, validate, and deploy advanced machine learning models and statistical algorithms for genomic data analysis.
• Lead the exploration and interpretation of complex, multi-modal datasets, including genomics, transcriptomics, and electronic health records.
• Design and implement data mining and predictive modeling strategies to identify novel biomarkers and therapeutic targets.
• Collaborate with cross-functional teams, including geneticists, bioinformaticians, clinicians, and software engineers, to define project goals and deliver data-driven solutions.
• Mentor and guide junior data scientists and researchers, fostering a culture of scientific rigor and technical excellence.
• Stay current with the latest advancements in data science, machine learning, genomics, and related fields.
• Communicate complex findings and insights effectively to both technical and non-technical stakeholders.
• Contribute to the intellectual property portfolio through publications and patent applications originating from Rustenburg, North West.

Requirements

• Ph.D. in Data Science, Computer Science, Statistics, Bioinformatics, or a closely related quantitative discipline.
• A minimum of 8 years of hands-on experience in data science, with a strong emphasis on machine learning and statistical modeling in a biological or healthcare context.
• Proven track record of developing and deploying predictive models for complex biological data.
• Proficiency in programming languages such as Python or R, and experience with relevant data science libraries (e.g., scikit-learn, TensorFlow, PyTorch, pandas, NumPy).
• Experience with large-scale data processing and database technologies (SQL, NoSQL).
• Demonstrated ability to manage data science projects from inception to deployment.
• Strong understanding of genomics, genetics, and common bioinformatics tools and databases.
• Excellent analytical, problem-solving, and communication skills.
• Previous research or work experience within Rustenburg, North West is a plus.

Benefits

Our client offers a highly competitive compensation package, including a generous base salary, performance-based bonuses, and comprehensive benefits such as medical, dental, and vision insurance, and a robust retirement savings plan. We provide ample opportunities for professional growth through conferences, workshops, and continuous learning initiatives. The work environment is dynamic and intellectually stimulating, fostering collaboration and innovation. Employees benefit from access to state-of-the-art facilities and advanced computational resources in Rustenburg, North West. We are committed to work-life balance and offer flexible working arrangements. Relocation support is available for qualified candidates.