Principal Computational Chemist - Molecular Modeling

Placements24; Sandton; Hybrid; ZAR 1,500,000 - 2,100,000; Full time

Job summary

Placements24 is seeking a Principal Computational Chemist for a fully remote role in South Africa. The position centers on advanced molecular modeling and simulation to drive drug discovery and the design of novel therapeutics.

You will lead projects, develop and validate computational models, and collaborate with medicinal chemistry and structural biology teams to shape the strategic direction of computational chemistry research in a highly collaborative environment.

Job description

About the Role

Our client, a leading biopharmaceutical research organization, is actively seeking a Principal Computational Chemist for a fully remote position. This role is critical for advancing our drug discovery efforts through the application of sophisticated molecular modeling and simulation techniques. You will lead projects focused on designing novel therapeutics, predicting compound properties, and understanding molecular interactions. Key responsibilities include developing and validating computational models, collaborating with medicinal chemistry and structural biology teams, and contributing to the strategic direction of computational chemistry research. The ideal candidate will possess extensive experience in molecular dynamics, quantum mechanics, QSAR, and fragment-based drug design, along with strong programming skills and expertise in relevant software packages. This is an exceptional opportunity to make significant contributions to drug discovery from a remote setting, working with a highly collaborative and innovative team. We are committed to scientific excellence and fostering a supportive remote work culture.