Principal Biochemist - Drug Discovery

Placements24; Durban; Ibrido; ZAR 1.800.000 - 2.800.000; Tempo pieno

Vantaggi offerti da questo lavoro

Competitive salary

State-of-the-art facilities

Professional growth in Durban

Collaborative work environment

Descrizione del lavoro

Placements24 is seeking a distinguished Principal Biochemist to join our Drug Discovery team in Durban. You will design and execute complex biochemical assays, lead research projects, and collaborate with multidisciplinary teams to accelerate therapeutics.

The role requires a PhD with 8+ years in pharma/biotech, expertise in enzyme kinetics, protein purification, and mentoring junior scientists. State-of-the-art labs and a collaborative environment await.

Competenze

• PhD in Biochemistry, Pharmacology, or a related field required.
• Minimum 8 years of progressive research experience in pharma/biotech.
• Expertise in enzyme kinetics, protein purification, structural biology, and biophysical techniques.
• Experience designing and executing complex biochemical experiments; HTS experience desirable.

Mansioni

• Lead the design, development, and optimization of biochemical and enzymatic assays for drug discovery.
• Investigate disease mechanisms and identify therapeutic intervention points.
• Analyze complex biochemical data with rigorous scientific standards.
• Collaborate with medicinal chemistry, biology, and pharmacology teams to advance leads.
• Mentor junior scientists and influence drug discovery strategy.
• Prepare reports, contribute to patents, and present at scientific forums.

Conoscenze

Enzyme kinetics

Protein purification

Structural biology

Biophysical techniques

Data analysis

Project leadership

Formazione

PhD in Biochemistry/Pharmacology

Strumenti

High-throughput screening (HTS)

Descrizione del lavoro

About the Role

Our client is seeking a distinguished Principal Biochemist to join their dynamic Drug Discovery team in Durban . This senior position is crucial for driving innovative approaches in identifying and validating novel drug targets. You will play a key role in designing and executing complex biochemical assays, leading critical research projects, and collaborating with multidisciplinary teams to accelerate the development of new therapeutics. The ideal candidate possesses extensive experience in biochemical techniques, a profound understanding of disease mechanisms, and a passion for scientific innovation, contributing to a culture of discovery and excellence in pharmaceutical research.

Key Responsibilities

• Lead the design, development, and optimization of biochemical and enzymatic assays for drug discovery screening.
• Investigate molecular mechanisms of disease and identify potential therapeutic intervention points.
• Analyze and interpret complex biochemical data, ensuring the highest standards of scientific rigor.
• Collaborate closely with medicinal chemists, biologists, and pharmacologists to advance lead compounds.
• Mentor junior scientists and contribute to the strategic direction of the drug discovery pipeline.
• Prepare high-quality scientific reports, contribute to patent applications, and present findings at key scientific forums.

Requirements

• Ph.D. in Biochemistry, Pharmacology, or a related field with a strong focus on drug discovery .
• A minimum of 8 years of progressive research experience in the pharmaceutical or biotechnology industry.
• Expertise in enzyme kinetics, protein purification, structural biology, and biophysical techniques.
• Proven ability to design and execute complex biochemical experiments and analyze results.
• Experience with high-throughput screening (HTS) methodologies is highly desirable.
• Strong leadership skills and a proven track record of successful project management and scientific publication.

Benefits

• Highly competitive salary and comprehensive benefits package.
• Opportunity to work on impactful projects in a leading research organization.
• Support for continuous learning and professional growth in Durban .
• State-of-the-art laboratory facilities and cutting-edge instrumentation.
• A stimulating and collaborative work environment dedicated to advancing medicine.