Pharmaceutical Chemist - Formulation Development - Benoni

Placements24; Benoni; On-site; ZAR 900,000 - 1,200,000; Full time

Benefits offered by this job

Competitive salary

Medical and dental coverage

Retirement savings plan

Professional development opportunities

Job summary

Placements24 in Benoni, South Africa, seeks a Pharmaceutical Chemist specializing in Formulation Development to join its R&D team. The role focuses on designing, developing, and optimizing dosage forms to deliver stable, effective medicines, collaborating with scientists across disciplines.

You will drive pre-formulation studies, perform scale-up, validate analytical methods (HPLC, dissolution, particle size, microscopy), and document development reports while ensuring regulatory compliance and

Qualifications

• Master's or PhD in Pharmaceutical Sciences, Pharmaceutics, Chemistry, or a closely related field.
• Minimum of 4 years of hands-on experience in pharmaceutical formulation development.
• Proven expertise in designing and developing dosage forms.
• Strong understanding of physical chemistry, materials science, and pharmaceutical technology.
• Proficiency in analytical techniques used for formulation characterization (HPLC, dissolution testing, particle size analysis, microscopy).
• Experience with laboratory equipment and pilot-scale manufacturing equipment.
• Excellent documentation, reporting, and presentation skills.
• Ability to work independently and collaboratively in a team-oriented research environment.
• Knowledge of regulatory requirements (ICH guidelines) related to drug product development.

Responsibilities

• Design and develop new pharmaceutical formulations for various dosage forms (e.g., tablets, capsules, injectables, topical).
• Investigate and optimize existing formulations to improve stability, bioavailability, and patient compliance.
• Conduct pre-formulation studies, including characterization of active pharmaceutical ingredients (APIs) and excipients.
• Perform formulation trials, scale-up studies, and manufacturing process development.
• Utilize various analytical techniques to characterize formulated products and assess their quality attributes.
• Develop and validate analytical methods for formulation testing.
• Prepare comprehensive documentation, including formulation development reports, protocols, and manufacturing instructions.
• Collaborate with R&D, analytical development, quality assurance, and manufacturing teams to ensure successful product development and transfer.
• Stay updated on the latest advancements in pharmaceutics, drug delivery systems, and relevant scientific literature.
• Troubleshoot formulation-related issues and propose effective solutions.

Skills

Formulation development

Analytical understanding

Documentation

Team collaboration

Problem solving

Regulatory knowledge

Education

Master's or PhD in Pharmaceutical Sciences/Pharmaceutics/Chemistry

Tools

HPLC

Dissolution testing

Particle size analysis

Microscopy

Job description

About the Role

Our client, a dynamic pharmaceutical company focused on innovative drug development, is seeking a talented Pharmaceutical Chemist specializing in Formulation Development to join their research and development team in Benoni . This role is critical in designing, developing, and optimizing stable and effective dosage forms for new and existing pharmaceutical products. The successful candidate will possess a strong foundation in pharmaceutics, expertise in formulation techniques, and a passion for bringing novel therapies from concept to reality. You will work closely with a multidisciplinary team of scientists and researchers in our state-of-the-art laboratories. We are committed to advancing pharmaceutical science and require individuals who are driven by innovation and scientific rigor. This is an excellent opportunity to contribute to the creation of high-quality medicines that improve patient lives.

Key Responsibilities

• Design and develop new pharmaceutical formulations for various dosage forms (e.g., tablets, capsules, injectables, topical).
• Investigate and optimize existing formulations to improve stability, bioavailability, and patient compliance.
• Conduct pre-formulation studies, including characterization of active pharmaceutical ingredients (APIs) and excipients.
• Perform formulation trials, scale-up studies, and manufacturing process development.
• Utilize various analytical techniques to characterize formulated products and assess their quality attributes.
• Develop and validate analytical methods for formulation testing.
• Prepare comprehensive documentation, including formulation development reports, protocols, and manufacturing instructions.
• Collaborate with R&D, analytical development, quality assurance, and manufacturing teams to ensure successful product development and transfer.
• Stay updated on the latest advancements in pharmaceutics, drug delivery systems, and relevant scientific literature.
• Troubleshoot formulation-related issues and propose effective solutions.

Requirements

• Master's or Ph.D. degree in Pharmaceutical Sciences, Pharmaceutics, Chemistry, or a closely related field.
• Minimum of 4 years of hands-on experience in pharmaceutical formulation development.
• Proven expertise in designing and developing various dosage forms.
• Strong understanding of physical chemistry, material science, and pharmaceutical technology.
• Proficiency in analytical techniques used for formulation characterization (e.g., HPLC, dissolution testing, particle size analysis, microscopy).
• Experience with laboratory equipment and pilot-scale manufacturing equipment.
• Excellent documentation, reporting, and presentation skills.
• Ability to work independently and collaboratively in a team-oriented research environment.
• Strong problem-solving abilities and a creative approach to formulation challenges.
• Knowledge of regulatory requirements (e.g., ICH guidelines) related to drug product development.

Benefits

• Our client offers a competitive salary package, including comprehensive medical and dental coverage, a retirement savings plan, and performance-based incentives.
• This position in Benoni provides access to cutting-edge research facilities and opportunities for professional growth, including attending scientific conferences and further training.
• Join a forward-thinking pharmaceutical company dedicated to innovation and patient well-being.
• Our client fosters a collaborative research environment where scientific contributions are recognized and rewarded.