Pharma Production Lead: Quality, Ops & Compliance

Talent Recruitment & Consulting (Pty) Ltd; Gauteng; On-site; ZAR 1,000,000 - 1,800,000; Full time

Job summary

Roche in South Africa seeks a Strategy Enabling Lead - mQMS Portfolio Manager to shape and execute strategic initiatives for the DIA global quality management system, the mQMS. The role drives centralized governance, prioritization, and release management of the global pipeline, interfacing with Quality, Regulatory, Compliance and Operations to convert requirements into an actionable roadmap.

You will balance resources, align senior leaders, and ensure initiatives are sequenced to maximize

Responsibilities

• Establish, maintain, and continuously refine a unified global change and continuous improvement portfolio across the global quality management system.
• Facilitate strategic portfolio prioritization sessions with executive stakeholders and functional leads; evaluate proposed change initiatives based on strategic impact, delivery risk, resource availability, and value generation.
• Define, deploy, and enforce standard intake criteria—including Definition of Ready (DoR) and Definition of Done (DoD)—to govern initiative submission, bundling, and deployment readiness.
• Design and maintain the master portfolio release pipeline to prevent overlapping deployments, leverage synergies.

Job description

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

As the Strategy Enabling Lead - mQMS Portfolio Manager, you will play a pivotal role in shaping and executing the strategic landscape for the Roche DIA global quality management system, the mQMS. You will lead the strategic centralization, prioritization, and release management of our global pipeline and continuous improvement portfolio ensuring cohesive and end to end value chain implementation.
In this high‑visibility role, you will bridge strategic vision and operational execution. You will orchestrate enterprise‑level portfolio governance, align senior cross‑functional leaders, and optimize capacity allocation-ensuring that every system initiative is sequenced to deliver maximum business value while minimizing organizational and system disruption, and maintaining compliance.
Operating at the heart of our matrix organization, you will apply rigorous portfolio management disciplines within our global environment. You will partner closely with subject matter experts in Quality, Regulatory, Compliance, Training, and Operations to translate complex compliance and system requirements into a structured, executable roadmap. Together with key leadership teams, you will balance resource constraints and turn our portfolio into a streamlined, business‑enabling asset.
If you excel at bringing structure to multi‑faceted portfolios, optimizing resource capacity, and leading strategic alignment in a matrixed environment, this role offers an exceptional platform to drive lasting enterprise impact.

The Opportunity

Enterprise Portfolio Governance & Strategic Alignment

• Establish, maintain, and continuously refine a unified global change and continuous improvement portfolio across the global quality management system.
• Facilitate strategic portfolio prioritization sessions with executive stakeholders and functional leads; evaluate proposed change initiatives based on strategic impact, delivery risk, resource availability, and value generation.
• Define, deploy, and enforce standard intake criteria-including Definition of Ready (DoR) and Definition of Done (DoD)-to govern initiative submission, bundling, and deployment readiness.

Centralized Scheduling & Capacity Optimization

• Design and maintain the master portfolio release pipeline to prevent overlapping deployments, leverage synergies