Lead Analytical Monitor

ICON Strategic Solutions; South Africa; On-site; ZAR 600 000 - 800 000; Full time

Job summary

A global healthcare organization in South Africa is looking for a Lead Analytical Monitor to ensure the integrity of clinical trials through analytical monitoring. You will conduct data reviews to identify risks, collaborate with cross-functional teams, and ensure compliance with regulatory standards. The ideal candidate has at least 4 years of experience in clinical data analysis and strong communication skills, along with a relevant degree. The role offers competitive salaries and a range of benefits aimed at ensuring work-life balance.

Benefits

Various annual leave entitlements

Health insurance offerings

Competitive retirement planning

Global Employee Assistance Programme

Flexible optional benefits

Qualifications

• Approximately 4+ years of experience within the Pharmaceutical, Biotech, or CRO industry.
• Strong understanding of clinical trial operations and data flow.
• Experience working with technology platforms for clinical data collection.

Responsibilities

• Perform analytical monitoring activities for assigned clinical trials.
• Conduct regular site/subject-level data reviews.
• Collaborate with cross-functional partners for effective risk management.

Skills

Data analysis

Communication skills

Project management

Organizational skills

Education

Bachelor’s degree in Health Sciences or Data Sciences

Job description

Lead Analytical Monitor South Africa

ICON plc is a world‑leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development.

What you will be doing

• Performing analytical monitoring activities for assigned clinical trials, ensuring early identification of site‑and subject‑level risks, trends, and data quality issues.
• Conducting regular, fit‑for‑purpose site/subject‑level data reviews to detect early warning signals and prevent issue recurrence.
• Accessing and analysing data from multiple systems, reporting tools, platforms, and databases to derive insights that support informed decision‑making.
• Collaborating closely with Site Managers, Central Monitoring, and other cross‑functional partners to influence site prioritisation and guided risk management.
• Ensuring all activities are conducted in full compliance with relevant SOPs, ICH‑GCP requirements, regulatory standards, and project timelines.
• Communicating effectively across multiple stakeholders, managing parallel workstreams, and escalating issues through established pathways.
• Providing training, guidance, and mentoring to junior Analytical Monitors to support capability development across the team.

Your profile

• Bachelor’s degree in Health Sciences, Data Sciences, or a related discipline; a Master’s degree is preferred.
• Approximately 4+ years of experience within the Pharmaceutical, Biotech, or CRO industry.
• Strong understanding of clinical trial operations, study execution, and data flow within clinical research.
• Demonstrated experience in data analysis within a clinical research environment, including familiarity with core statistical concepts.
• Project, issue, and risk management experience, with the ability to apply critical thinking to drive solutions and support decision‑making.
• Experience working with technology platforms and systems used for clinical data collection, analysis, and reporting.
• Excellent communication and interpersonal skills, with the ability to collaborate effectively across global cross‑functional.
• Strong organisational skills, with the ability to manage multiple priorities in a fast‑paced environment.
• Excellent verbal and written communication skills in English.

What ICON can offer you

Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well‑being and work life balance opportunities for you and your family.

Our benefits examples include:

• Various annual leave entitlements
• A range of health insurance offerings to suit you and your family’s needs.
• Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
• Global Employee Assistance Programme, LifeWorks, offering 24‑hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family’s well‑being.
• Life assurance
• Flexible country‑specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.

At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here.

Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless - there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles.