Wet Lab Staff Scientist

MyOme; Menlo Park (CA); On-site; USD 170,000 - 185,000; Full time

Benefits offered by this job

Healthcare

401K

Unlimited PTO

Professional development

Off-sites and team meals

Job summary

MyOme is seeking a senior wet lab scientist to lead RNASeq integration into the clinical workflow. The role includes developing and validating assays, coordinating with automation and bioinformatics teams, and mentoring wet lab staff.

You will shape the RNASeq strategy and expand the assay portfolio while ensuring compliance with CLIA/CAP standards where applicable. Located onsite in Menlo Park, the role offers a competitive salary with equity.

Qualifications

• PhD required or equivalent practical experience with strong wet lab focus.
• 8+ years of hands-on RNASeq and NGS experience in a clinical/testing context.
• Experience standing up clinical assays and working toward regulatory readiness (CLIA/CAP a plus).
• Strong collaboration across wet lab, bioinformatics, clinical, and engineering teams.

Responsibilities

• Lead development and validation of RNASeq assays for clinical testing.
• Create comprehensive project plans covering milestones, hiring, validation, budget, and QC.
• Collaborate with automation engineers to design scalable wet lab workflows.
• Align wet lab processes with downstream data analysis and pipelines.
• Mentor wet lab staff and guide assay development and validation efforts.
• Expand the in-house assay portfolio over time with new technologies.
• Present progress to senior leadership and guide IP strategy.

Skills

RNASeq

NGS

Project planning

Regulatory awareness

Education

PhD in Molecular Biology, Genomics, Biochemistry, or related

Tools

RNASeq platforms

Proteomics (optional)

Job description

MyOme’s mission is to provide clinically actionable genetic information to patients throughout their lives. We combine clinical-grade whole genome sequencing, advanced AI methods for genome interpretation, and seamless digital tools for doctors and patients to order and access results. Our team is composed of seasoned entrepreneurs, scientists, and operators, and we’re backed by top-tier investors.

Position Overview:

MyOme is seeking an experienced and innovative senior wet lab scientist who can bothguide development efforts and contribute to our NGS assay development roadmap. Thisperson will initially lead efforts to incorporate RNASeq into MyOme’s clinical testingworkflow and evaluate additional new technologies. The ideal candidate has provenexperience standing up clinical NGS assays and is able to think critically and creativelyto deliver results.

What You’ll Do:

• Develop a comprehensive project plan for bringing RNASeq in house, coveringdevelopment milestones, hiring needs, validation strategy, budget, and qualitycontrol
• Lead the technical development and validation of RNASeq assays, ensuring theymeet MyOme’s quality and performance standards
• Partner with automation engineers to design efficient, scalable wet lab workflowssuited for clinical scale throughput and collaborate with clinical lab staff to ensurenew assays meet regulatory and clinical laboratory requirements
• Work closely with the research bioinformatics team to align wet lab processeswith downstream data analysis and pipeline needs
• Mentor and guide wet lab scientists, providing technical direction on assaydevelopment and validation work
• Expand the in house assay portfolio over time by leading evaluation and (ifwarranted) development efforts for additional assays (e.g. Illumina TruPath,proteomics)
• Present project plans, progress, and findings to senior leadership
• Guide the publication and presentation plan for assay components as well as IPstrategy

What You’ll Ne** ed:

• Advanced degree (PhD) in Molecular Biology, Genomics, Biochemistry, or arelated field, or equivalent practical experience
• 8+ years of wet lab experience, including hands-on work with RNASeq and nextgeneration sequencing technologies. Experience with additional analytes (e.g.,proteomics, methylation) is a plus
• Experience developing and executing project plans that include technicaldevelopment, validation, budget, and quality control components
• Familiarity with clinical laboratory requirements and standards (e.g., CLIA/CAP)and experience bringing assays to a scalable and clinically ready state
• Strong collaboration skills, with experience working across wet lab,bioinformatics, clinical, and engineering teams
• Excellent communication skills and ability to articulate scientific and technical concepts to non-experts

Location, Compensation, and Benefits:

• Location: Onsite at our Menlo Park, CA laboratory campus
• Compensation: Annual salary range is $170,000 - $185,000, commensurate with experience. This role is also eligible for equity.

San Francisco Bay Area pay range

$170,000—$185,000 USD

Benefits:

• Comprehensive healthcare coverage (Health, Dental, and Vision)
• 401K
• Unlimited PTO
• Professional development opportunities
• Company-sponsored off-sites and team meals during in-person meetings
• Direct access to company leadership and the opportunity for career growth

Diversity, Inclusion, and Equal Opportunity:

MyOme values diversity in all forms. We believe that diverse perspectives drive better science and better patient outcomes. We are an Equal Opportunity Employer committed to creating an inclusive workplace that empowers every individual.

Why Work at MyOme?

Join us if you:

• Want to make an impact at the intersection of healthcare and technology, changing the way people engage with their health at the genetic level
• Enjoy rolling up your sleeves, taking initiative, and being empowered to lead
• Value humility, transparency, and collaborative problem-solving
• Thrive in fast-moving, dynamic environments with smart, driven teammates
• Appreciate competitive compensation, meaningful equity, and excellent benefits

Learn More: myome.com