Wet Lab Staff Scientist

MyOme; Menlo Park (CA); On-site; USD 170,000 - 185,000; Full time

Benefits offered by this job

Healthcare coverage

401K

Unlimited PTO

Professional development opportunities

Team off-sites and leadership access

Job summary

MyOme is seeking a senior wet lab scientist to lead RNASeq integration into the clinical testing workflow. The role focuses on standing up clinical NGS assays, with involvement across wet lab, automation, and bioinformatics teams at our Menlo Park campus.

You will mentor scientists, guide assay development, and help expand the in-house portfolio, including potential TruPath and proteomics projects. Equity is offered alongside a competitive salary.

Qualifications

• PhD in a related field or equivalent practical experience.
• 8+ years wet lab experience with RNASeq and NGS.
• Experience planning and executing technical development and validation projects.
• Familiarity with CLIA/CAP clinical lab requirements.
• Strong cross-functional collaboration and communication skills.

Responsibilities

• Lead RNASeq development and validation for clinical workflow.
• Create an in-house RNASeq project plan with milestones and budget.
• Collaborate with automation engineers to design scalable workflows.
• Coordinate with bioinformatics to align wet lab and data analysis.
• Mentor wet lab scientists and expand assay portfolio over time.
• Present plans and progress to senior leadership.

Skills

RNASeq experience

NGS technologies

Project planning

CLIA/CAP familiarity

Collaboration

Communication skills

Education

PhD in Molecular Biology / Genomics / Biochemistry (or equivalent)

Tools

Illumina TruPath

Illumina sequencing

Job description

MyOme’s mission is to provide clinically actionable genetic information to patients throughout their lives. We combine clinical-grade whole genome sequencing, advanced AI methods for genome interpretation, and seamless digital tools for doctors and patients to order and access results. Our team is composed of seasoned entrepreneurs, scientists, and operators, and we're backed by top-tier investors.

Position Overview

MyOme is seeking an experienced and innovative senior wet lab scientist who can both guide development efforts and contribute to our NGS assay development roadmap. This person will initially lead efforts to incorporate RNASeq into MyOme’s clinical testing workflow and evaluate additional new technologies. The ideal candidate has proven experience standing up clinical NGS assays and is able to think critically and creatively to deliver results.

What You’ll Do

• Develop a comprehensive project plan for bringing RNASeq in house, covering development milestones, hiring needs, validation strategy, budget, and quality control
• Lead the technical development and validation of RNASeq assays, ensuring they meet MyOme's quality and performance standards
• Partner with automation engineers to design efficient, scalable wet lab workflows suited for clinical scale throughput and collaborate with clinical lab staff to ensure new assays meet regulatory and clinical laboratory requirements
• Work closely with the research bioinformatics team to align wet lab processes with downstream data analysis and pipeline needs
• Mentor and guide wet lab scientists, providing technical direction on assay development and validation work
• Expand the in house assay portfolio over time by leading evaluation and (if warranted) development efforts for additional assays (e.g. Illumina TruPath, proteomics)
• Present project plans, progress, and findings to senior leadership
• Guide the publication and presentation plan for assay components as well as IP strategy

What You’ll Need

• Advanced degree (PhD) in Molecular Biology, Genomics, Biochemistry, or a related field, or equivalent practical experience
• 8+ years of wet lab experience, including hands‑on work with RNASeq and next generation sequencing technologies. Experience with additional analytes (e.g., proteomics, methylation) is a plus
• Experience developing and executing project plans that include technical development, validation, budget, and quality control components
• Familiarity with clinical laboratory requirements and standards (e.g., CLIA/CAP) and experience bringing assays to a scalable and clinically ready state
• Strong collaboration skills, with experience working across wet lab, bioinformatics, clinical, and engineering teams
• Excellent communication skills and ability to articulate scientific and technical concepts to non-experts

Location, Compensation, and Benefits

• Location: Onsite at our Menlo Park, CA laboratory campus
• Compensation: Annual salary range is $170,000 - $185,000, commensurate with experience. This role is also eligible for equity.

San Francisco Bay Area pay range: $170,000 USD - $185,000 USD

Benefits

• Comprehensive healthcare coverage (Health, Dental, and Vision)
• 401K
• Unlimited PTO
• Professional development opportunities
• Company-sponsored off-sites and team meals during in‑person meetings
• Direct access to company leadership and the opportunity for career growth

Diversity, Inclusion, and Equal Opportunity

MyOme values diversity in all forms. We believe that diverse perspectives drive better science and better patient outcomes. We are an Equal Opportunity Employer committed to creating an inclusive workplace that empowers every individual.

Why Work at MyOme?

Join us if you:

• Want to make an impact at the intersection of healthcare and technology, changing the way people engage with their health at the genetic level
• Enjoy rolling up your sleeves, taking initiative, and being empowered to lead
• Value humility, transparency, and collaborative problem‑solving
• Thrive in fast‑moving, dynamic environments with smart, driven teammates
• Appreciate competitive compensation, meaningful equity, and excellent benefits

Learn More: myome.com